38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2019
Cellular and Molecular Biology Third Award
The enzyme Fidgetin-like 2 (FL2) suppresses cell migration by severing intracellular filaments called microtubules (MTs). Mouse studies showed that depleting FL2 using small interfering RNA…
ISEF · 2019
Cellular and Molecular Biology
Background: Traditional chemical-based treatments for disease are non-specific and cause undesirable side effects. These non-target effects can be avoided by site-specific, targeted therapy…
ISEF · 2019
Cellular and Molecular Biology Third Award
Gefitinib, which is a small molecule tyrosine kinase inhibitor (TKI) of epithelial growth factor receptor (EGFR), is currently under investigation for colon cancer treatment. However, some p…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives This study examines epigenetic therapy as a treatment for slowing the growth of cancerous liver cells. In addition to having genetic and environmental causes, cancer can be consid…
ISEF · 2019
Cellular and Molecular Biology
This study examines epigenetic therapy as a treatment for slowing the growth of cancerous liver cells. More specifically, epigenetic changes such as the abnormal patterning of DNA hypo- and…
ISEF · 2019
Cellular and Molecular Biology
This experiment was designed not only from a continuation of a previous year, but as well as an improvement. Essential oils were present to prove that they have special and unique properties…
ISEF · 2019
Cellular and Molecular Biology
Angiogenesis is requisite for the growth and metastatic spread of solid tumors. Identifying pathological angiogenesis regulators will provide therapeutic targets against solid tumor growth.…
CSEF · 2019
Biochemistry/ Molecular Biology First Award
Objectives Does select natural remedies possess anticoagulating properties and how they compare with untreated samples in an in vitro study? The primary objective of this in vitro study was…
ISEF · 2019
Cellular and Molecular Biology
Currently, mutations in the BRCA1 and 2 genes are estimated to explain approximately 15 percent of hereditary breast cancer cases. However, studies have established that 50 percent of women…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives The objective of this experiment was to discover the effect of different masses of iron filings on the oxygen production of Thalassiosira diatoms (defined as the concentration of…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives Examine the effects of periodic, compressive mechanical loading administered via a mechanical pressure device on collagen fiber orientation and fibroblast proliferation. Methods T…
CSEF · 2019
Product Science (Biological) (Junior Division Only) Honorable_mention Award
Objectives People all around the world enjoy eating eggs, but may be overwhelmed by so many choices. Free-Range? Cage-Free? Organic? To address this question, we decided to test the nutritio…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives The purpose of this research is to look for possible common ITS sequences among nine well-known Traditional Chinese Herbal Medicine with similar analgesic and sedative effects on…
ISEF · 2019
Cellular and Molecular Biology
Gastric cancer is one of the most common causes of cancer related deaths, yet little is known about the molecular drivers behind the progression of normal stomach to gastric cancer. GATA4 an…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives The objective of this project was to reprogram Mucopolysaccharidosis (MPS) IIIA human fibroblast cells into induced pluripotent stem cells, then correct the MPS IIIA genetic defic…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives Lung cancer is one of the leading causes of cancer-related deaths worldwide. In recent years, the advent of targeted, biological therapies such as EGFR-TKI offers the most promisi…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives This experiment was created to measure the level of gluten in different flours. It was expected that the Bread flour would have the most gluten and the Gluten Free flour would hav…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives In this project silver nanoparticles have been synthesized from silver nitrate using Asparagus extract containing the flavonoid, quercetin (a green synthesis). The objective was t…
ISEF · 2019
Cellular and Molecular Biology
Inhibitor of DNA binding 2, or Id2, is a protein that is required for hematopoietic stem cell (HSC) maintenance and self-renewal capacity. A positive feedback loop has been identified involv…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives The objective of this study is to determine how different types of flour in sourdough starter affect the resulting bread. Methods 5 different types of flour (rye, whole wheat, unb…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives The purpose of my project is to figure out why some people have a better response to drugs than others. Methods Materials: Laptop, Writing Utensils, Notecards, PharmGKB.org, NCBI…
CSEF · 2019
Product Science (Biological) (Junior Division Only)
Objectives The objective of this study is to determine the effectiveness of sunscreens with varying SPF values over the course of 2 hours and if the higher SPF value corresponds to better pr…
CSEF · 2019
Product Science (Biological) (Junior Division Only)
Objectives I want to see if a glucometer, commonly used by diabetics, can be used to accurately determine whether or not a drink has glucose in it and can it tell how much glucose is in a dr…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives The objective of my study was to determine if temperature had an effect on the amount of light produced by E-Coli bacteria genetically modified to produce Green Florescent Protein…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives The objective of this experiment is to determine how different stomach pH levels affect the rate iron is dissolved from an iron-rich food. Methods Almond meal, hydrochloric acid,…
ISEF · 2019
Cellular and Molecular Biology
Over 70% of breast cancer patients’ cells express the estrogen receptor (ER), which promotes the proliferation of cancer cells, by activating the expression of tumor-promoting genes. In the…
ISEF · 2019
Cellular and Molecular Biology
Probiotic bacteria have been intensively studied for their role in the gut microbiome and digestion. Research into the abilities of probiotic bacteria to fight pathogens is also a growing ar…
ISEF · 2019
Cellular and Molecular Biology
Alzheimer’s is a progressive neurological disorder that affects memory and is the third leading cause of death. Downregulation of apolipoprotein E (ApoE) gene is involved in late-onset Alzhe…
ISEF · 2019
Cellular and Molecular Biology Third Award
Worldwide, stroke is the second leading cause of death and the third leading cause of disability. There is a striking lack of therapeutic interventions after the first few hours of stroke on…
CSEF · 2019
Biochemistry/ Molecular Biology
Objectives -Create a positive control for the genetic cross by electroporating CC4696+ cells with the rbcL gene and isolating colonies that have been functionally complemented. -Optimize Chl…