Browse real student projects, abstracts, and awards.
ISEF · 2022
Plant Sciences Second Award
Legumes form root nodules in which nitrogen-fixing bacteria are housed and flavonoids are necessary to activate nodulation genes in rhizobia. Isoflavonoids are known to protect legumes from…
ISEF · 2022
Computational Biology and Bioinformatics Second Award
With the lowest 5-year survival rate (9%) among all types of cancer, pancreatic cancer is considered one of the most lethal diseases in the world. Current conventional treatments often fail…
ISEF · 2022
Engineering Technology: Statics & Dynamics Second Award
Climate change can be solved, but the window is closing. 90% of goods move by cargo ships, resulting in 4% of climate change emissions. There is a need for climate change technology that wor…
ISEF · 2022
Translational Medical Science Second Award
Alzheimer's disease (AD) is characterized by toxic aggregates formed by amyloid beta (AB) and tau, which kill memory and learning neurons. With only symptomatic treatments for mild-moderate…
ISEF · 2022
Biomedical and Health Sciences Second Award
Cardiovascular diseases are the most common cause of death in the world. Because humans form few cardiomyocytes post-birth, engineering new myocardium could transform the treatment of heart…
ISEF · 2022
Translational Medical Science Second Award
This study evaluated the cytotoxicity of two Centella asiatica (CA) methanolic leaf extracts on the metastatic, triple negative breast cancer (TNBC) cell line MDA-MB-231. CA is a plant regio…
ISEF · 2022
Cellular and Molecular Biology Second Award
A growing area of research is focused on identifying drugs that have differential cytotoxic effects on normal and cancer cells. Pomegranate polyphenols are potent antioxidants and has antica…
ISEF · 2022
Plant Sciences Second Award
Global warming and the rapidly growing world population are among the most serious issues that threaten global food security. A new approach to support plant productivity is through exploiti…
ISEF · 2022
Computational Biology and Bioinformatics Second Award
Background: Cavendish banana production is seriously threatened by Fusarium wilt tropical race 4, characterized by leaf decay patterns detectable through image recognition technology. Althou…
ISEF · 2022
Behavioral and Social Sciences Second Award
In Zimbabwe, only 19% of female students graduate from STEM (science, technology, engineering, and mathematics) subjects, compared to 39% of male students. This project unveils the barriers…
ISEF · 2022
Robotics and Intelligent Machines Second Award
According to the WHO, there are currently 2.2 billion people who live with visual impairment in the world. A sighted person is able to take in 3D spatial information by taking the 3D locatio…
ISEF · 2022
Chemistry Second Award
Silica capillaries have been an integral part of the instrumentation used in many areas of analytical chemistry for decades, especially in analytical separations. In most cases, they are use…
ISEF · 2022
Biomedical Engineering Second Award
Oral cancer is highly treatable when diagnosed at an early stage. In rural India, however, 60% of oral cancer cases are diagnosed with advanced stages. Mass screening requires experienced do…
ISEF · 2022
Translational Medical Science Second Award
The current practice of treating cancer with radiation, chemotherapy, and immunotherapy is a one-size-fits-all approach, in which patients with the same type and stage of cancer receive the…
ISEF · 2022
Biomedical and Health Sciences Second Award
Exosomes secreted by pediatric bone marrow mesenchymal stem cells (pBMSC-Exos) demonstrate optimal characteristics for bone tissue engineering. MSC-Exos of alternate origin have expedited bo…
ISEF · 2022
Physics and Astronomy Second Award
When a confetti cannon is fired, a turbulent spectacle follows: hundreds and hundreds of paper snippets swirl through the air in fantastic trajectories. When we looked at these more closely,…
ISEF · 2022
Earth and Environmental Sciences Second Award
In 2021, Hurricane Ida devastated much of New Orleans. Widespread power outages closed numerous dialysis centers, which provide critical services for patients with end stage renal disease (E…
ISEF · 2022
Energy: Sustainable Materials and Design Second Award
Pura Aer (PA) is an air purifier system that repurposes disposable face masks and integrates a peregrine falcon-inspired fan design. PA was developed in four phases, with design criteria set…
ISEF · 2022
Energy: Sustainable Materials and Design Second Award
In a standard silicon solar cell, the photovoltaic effect generates excited electrons which are transported to the surface of the cell. The problem of collecting these excited charges from t…
ISEF · 2022
Biomedical and Health Sciences Second Award
Existing drugs are being researched for novel repurposed usages to supplant the traditional, inefficient process of new drug discovery. Cephalexin is a cephalosporin antibiotic purported to…
ISEF · 2022
Systems Software Second Award
Most large applications eventually require user-defined behavior to remain adaptable to different users. Common approaches to user-defined behavior are configurations (for simple behavior) a…
ISEF · 2022
Behavioral and Social Sciences Second Award
Every 40 seconds, suicide steals a life—an annual cost of 800,000 people—but clinical assessments for suicide risk and treatment have improved little over the past 50 years. Risk assessments…
ISEF · 2022
Environmental Engineering Second Award
Carbon capture and conversion is one of the essential factors to reducing carbon dioxide (CO2) emissions and strengthening the economy. Current CO2 reducing catalysts face poor adsorption pr…
ISEF · 2022
Chemistry Second Award
Biodiesel fuel is an environmentally friendly replacement for petroleum-based diesel fuel. Energy-dense algae are more suitable feedstocks for biodiesel than current food crops and animal fa…
ISEF · 2022
Engineering Technology: Statics & Dynamics Second Award
The Buoy is a state-of-the-art pool alarm that is designed to be user-friendly, reliable, cost-effective, and a safety layer to prevent childhood drownings. Design goals were ease of use, re…
ISEF · 2022
Microbiology Second Award
Sounds influence on bacterial growth is a very new and unexplored research field. The field is still in its infancy and the question of whether sound and/or ultrasound is a growth inhibitor…
ISEF · 2022
Cellular and Molecular Biology Second Award
Methylmercury is a neurotoxin present in fish tissues that permeates the blood-brain barrier (BBB) after consumption. Previous research has shown that methylmercury is harmful to neurons, ca…
ISEF · 2022
Physics and Astronomy Second Award
The identity and behavior of the invisible dark matter, which constitutes most of the mass in the universe, is a central yet unresolved question at both the cosmological and quantum scales.…
ISEF · 2022
Earth and Environmental Sciences Second Award
Low-frequency noise from marine shipping is an underwater acoustic pollutant in oceans. The noise spectrum overlaps with frequencies marine mammals use to communicate and navigate, leading t…
ISEF · 2022
Physics and Astronomy Second Award
There is no general closed-form solution for the long-term dynamics of stars in systems where three or more stars are orbiting each other. When considering only the effects of Newtonian grav…