Translational Medical Science
Second Award
Neurodegenerative diseases like Alzheimer's affect millions worldwide, yet current diagnostic methods remain invasive, expensive, and largely inaccessible during the critical early intervent…
Chemistry
Second Award
The healthcare and pharmaceutical sectors play a critical role in combating various diseases affecting human and societal life. One of the diseases affecting many people today is tinea skin…
Chemistry
Second Award
Environmental contaminants, particularly bisphenols, have become increasingly widespread. As a result, global water pollution has become of greater concern. Water pollution has a profound ef…
Biomedical Engineering
Second Award
Gliomas remain the deadliest form of brain cancer, with patients surviving one year post-diagnosis on average, 5-year survival rates as low as 5%, and no major treatment advances in the past…
Translational Medical Science
Second Award
Neurodegenerative diseases, including Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI), are typically diagnosed after 50-80% neuronal loss, reflecting a critical failure of early…
Biomedical and Health Sciences
Second Award
Despite advances in immunotherapy, up to 60% of melanoma patients do not respond to treatment. Emerging evidence suggests that physical exercise enhances anti-tumor immunity; however, the mo…
Computational Biology and Bioinformatics
Second Award
Nearly 50% of human IVF embryos arrest before reaching the blastocyst stage, yet the molecular mechanisms causing this failure remain poorly understood. Current literature examines omics in…
Microbiology
Second Award
Restoring severely eutrophic waters, especially in hardened urban river channels, is challenging and costly due to algal blooms, turbidity, microbial overgrowth, oxygen depletion, and nutrie…
Mathematical Sciences (Senior Division)
Second Award
Our modern digital security rests on the difficulty and structure of prime factorization—a principle that has powered number theory for centuries. To understand the strengths and weaknesses…
Animal Sciences
Second Award
With 5.6 billion pounds of pesticides entering ecosystems annually, traditional monitoring methods such as soil and water sampling cannot cover large areas, cost $500–600 per sample, and tak…
Earth and Environmental Sciences
Second Award
Cyanobacterial harmful algal blooms (HABs) pose threats to aquatic ecosystems and public health, yet existing prediction models rely on single-variable correlative thresholds that fail to ca…
Plant Biology (Junior Division)
Second Award
Many people throw away their unfinished drinks on plants. This project looks at how water, coffee, lemonade, tea, and soda can affect the plant growth of cherry tomatoes, Thai Chili peppers,…
Technology Enhances the Arts
Second Award
This experiment aimed to create an Artificial Intelligence (AI) method that rates /s/ pronunciations comparable to a speech therapist, and more accurate than adults untrained in speech thera…
Plant Sciences
Second Award
Yaupon Holly and Yerba Mate are two economically important, caffeine-producing holly (i.e., Ilex) species in America. Yaupon Holly is native to North America and Yerba Mate is native to Sout…
Biomedical Engineering
Second Award
Ankle-foot prosthetics aim to recreate the biological motion of the ankle and restore natural gait to transtibial amputees. Achieving this requires motion in three dimensions and a variable-…
Applied Mechanics (Senior Division)
Second Award
Ankle-foot prosthetics aim to recreate the biological motion of the ankle and restore natural gait to transtibial amputees. Achieving this requires motion in all three biological planes and…
Computational Biology and Bioinformatics
Second Award
Structural comparison between proteins is key to many research tasks, including evolutionary analysis, peptidomimetics, and functional annotation. Traditional structure alignment tools such…
Engineering Technology: Statics & Dynamics
Second Award
Traditional figure skating jump-assist devices often require manual coach operation and lack adaptability to varying athlete heights and weights. This project developed a universal kinematic…
Robotics and Intelligent Machines
Second Award
Microplastics have a devastating effect on global ecosystems, however, conventional monitoring methods are expensive, inefficient, and cumbersome requiring week-long laboratory analyses, whi…
Computational Biology and Bioinformatics
Second Award
Drug–target interaction (DTI) prediction is a crucial step in modern drug discovery. Accurate and efficient predictions can substantially reduce costs and development time. While deep learni…
Microbiology (Junior Division)
Second Award
Plastic pollution of the human body is an increasing concern that requires a solution. One solution would be to introduce plastic digesting bacteria in our intestines to digest any microplas…
Computational Biology and Bioinformatics
Second Award
Resistance to targeted therapies in non-small cell lung cancer (NSCLC) limits treatment efficacy. Mathematical models have shown promise in predicting resistance development by capturing bio…
Environmental Engineering
Second Award
While global oil production exceeds 100 million barrels per day, over 40 million liters of crude oil have contaminated marine ecosystems since 2020, resulting in catastrophic ecological and…
Translational Medical Science
Second Award
The lack of rapid, accessible, and precise quantitative biomarkers for lesion grading remains the primary barrier to preventing cervical cancer—a leading cause of cancer death among women wo…
Biomedical Engineering
Second Award
Your mind works perfectly, but your body will not let you speak. Millions with Amyotrophic Lateral Sclerosis, stroke, or paralysis live trapped inside working minds. Today's brain-computer i…
Materials Science (Junior Division)
Second Award
Cities are often warmer than nearby rural areas because of the urban heat island effect, where buildings, roads, and rooftops absorb solar radiation during the day and release heat slowly at…
Animal Sciences
Second Award
Coral reefs are rapidly declining due to climate change and pollution, with more than 80% of reefs worldwide at risk of bleaching. However, current restoration efforts cannot ensure long-ter…
Materials Science
Second Award
Arsenic (As) is a known carcinogen, and its contamination of groundwater is a major global public health concern, with approximately 200 million people at risk of arsenic poisoning. Addressi…
Earth & Environmental Sciences(Senior Division)
Second Award
El Nino events are Pacific-originating oceanic-atmospheric phenomena that usher in shifts in global circulation and weather–shifts that in the past have spiked global grain prices 40%, spark…
Electronics & Electromagnetics (Senior Division)
Second Award
Adequate access to tactile resources such as braille and tactile images is one of the largest challenges towards improving the blind or visually impaired (BVI) education level and socially c…