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The Effects of Cannabidiol Oil on the Egg Hatching Rates of C. Elegans

AJAS · 2020

Gabrielle Anzalone, Esme Kimber · and

Overview

Cannabidiol (CBD) oil, is a substance whose use and popularity has increased significantly, as it has become a $270 million industry within the last few years. Despite the popularity of CBD oil, little research has been conducted on the safety and effects it has on our bodies. One of the few scientific studies on CBD oil was conducted by Emilio Perucca from the University of Pavia, suggesting CBD oil can help prevent seizures. Although lacking thorough scientific studies, CBD oil is believed to reduce inflammation, improve heart health, calm the nerves, and reduce pain. Some negative side effects associated with CBD oil include nausea, anxiety, dizziness, and mood changes. The goal of this study is to contribute to the understanding of the use of CBD oil for medical purposes and how CBD oil affects the body's response to stress. The specific factor examined in this study was whether CBD oil triggered a change in the hatching rates of the model organism Caenorhabditis elegans (C. elegans). C. elegans were the ideal model organism to use in this study because of their short lifespan, which allows for conducting an experiment that studies short-term effects of a substance on the body. The study monitored egg hatching rates because variations in egg hatching suggest the worms are under stress. In this study, the worms exposed to CBD oil had a hatching rate of 33%. The worms exposed to the control, MCT oil (coconut oil), had a hatching rate of 27%. The plates exposed to CBD oil showed no significant difference in egg hatching when compared to the control plates (p-value = 0.435). The data collected is preliminary, but suggests that CBD oil does not change the egg hatching rates of C. elegans. More research needs to be conducted on whether CBD oil may cause other stress responses in C. elegans or humans.

Competition history

  • AJAS 2020 Category not listed

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Source: AAAS Annual Meeting (Confex) / American Junior Academy of Science

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