PlaqueGuard: Investigating the Effects of Polyphenols on Dental Plaque Formation

Overview

Plaque is a widespread health problem leading to cavities, pain, gum disease, and eventual tooth loss. Many popular mouthwashes address this by using alcohol to nonselectively kill oral bacteria, including beneficial ones, which has been connected to issues ranging from irritation to potentially increased cancer risks. This highlights the need for a safer, more targeted approach. My project investigates natural compounds called polyphenols, found in green tea and cranberries, to reduce how sugars stick to teeth, preventing early stages of plaque formation. Testing was conducted on teethlike surfaces with a thin layer of egg white to accurately simulate the oral environment. Variations in sugar were measured by finding weight difference, and validated through image analysis with python. By targeting the problem at its source rather than eliminating bacteria entirely, this approach could be an effective solution that avoids the drawbacks of popular methods while maintaining a stable, healthy oral environment.

Awards (2)

• Silver Medal
• Selected for CWSF 2026

Competition history

• CWSF 2026 Health & Wellness

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