MgCl(2) Stimulating Effect on Osteogenesis and Promotion towards Bone Densification

Overview

Objectives/Goals The purpose of this experiment is to determine how magnesium chloride plays a role in the bone remodeling process, osteogenesis, and how its role differs from the effects of various other supplementary medications. Methods/Materials I used 15 cups (and bones) each containing 3 samples of the 5 variables: (per cup) 120 ml H2O; 120 ml H2O, 1g OsteoPhase; 120 ml H2O, 1g MgCl2; 120 ml H2O, 1g CaCl2, 120 ml H2O, 1g OsCal. The bones were submerged and left in their solutions for 4 months with periodic x-ray samples taken halfway between the experimental term and the end. Upon completion, the radiographs were taken to City of Hope to be analyzed with the bio-rad densitometer and an image density quantifier to determine density in OD (optical density.) Results Each of the radiographs produced very different results, suggesting that each of the supplements played a different role in bones, and by working by themselves, they proved to be very ineffective. However, in terms of density repair, every medication contributed to increasing density between term 1 and term 2. H2O bones increased by 14%, Osteophase bones increased by 6.7%, MgCl2 bones increased by 11.4%, CaCl2 bones increased by 15.9%, and OsCal bones increased by 27.2%. Conclusions/Discussion I believe that bone development (based on the radiograph observations) and repair is not singularly based on one mineral in order to not only sustain density but stabilize growth, especially during child/teenhood. Instead, the whole idea of bones is literally dealing with numerous elements and compounds, which work together in order to develop the structure that we refer to as, the framework of our body, our skeletal system. Although a single element may contain primary dominance in bones, without the other, it just will not work.

Competition history

• CSEF 2010 Pharmacology (Senior Division Only) · Entry S1814

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