Antibacterial Properties of Chitosan Nanoparticles Encapsulated by Cocos nucifera-derived Peptides

Overview

Objectives/Goals This study sought to identify the potential of a novel biocide system consisting of chitosan nanoparticles encapsulated by the peptides found in green coconut water (GCW). Methods/Materials Through ionotropic gelation, chitosan nanoparticles were formed and mixed with filtered green coconut water (GCW) to promote encapsulation. The physiochemical properties of the biocides were analyzed through zeta potential and particle sizing analyses. A bacterial bioassay was conducted to determine the antibacterial properties of the combined biocides against Pseudomonas putida, a surrogate environmental bacteria strain. Results The biocide system was shown to be less effective against P. putida when compared to the antibacterial activity of chitosan nanoparticles, but more bactericidal in comparison to the GCW peptides. Conclusions/Discussion Chitosan nanoparticles were re-asserted as efficient dose-dependent biocides while the absence of antimicrobial activity from the GCW peptides suggested the need for purification and isolation of the peptides. Thus, the novel composite of the GCW peptides and the chitosan nanoparticles did not significantly enhance the antibacterial properties of the individual bactericides as hypothesized.

Awards (1)

• Honorable Mention

Competition history

• CSEF 2010 Pharmacology (Senior Division Only) · Entry S1808

Resources

• CSEF project summary ↗

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