11705 projects whose affiliated fair was here, most recently in 2026.
ISEF records a state or province for some finalists and not others, so these counts do not add up to the country total.
11705 projects · showing 1411–1440
ISEF · 2025
Engineering Technology: Statics & Dynamics
The engineering goal of my project is to make and test the efficiency of an ion propulsion device. The trials will include multiple variables such as same terminal shape/spacing and the way…
ISEF · 2025
Microbiology
Microplastic pollution presents a significant environmental challenge, particularly in soil ecosystems, where its effects on microbial communities remain poorly understood. This study aimed…
ISEF · 2025
Computational Biology and Bioinformatics
Neurodegenerative disease therapeutic development faces hurdles from multi-omic complexity and the poor interpretability of standard ML models (e.g., MLPs), limiting target discovery. We dev…
ISEF · 2025
Mathematics
In traditional Sudoku, players are tasked with filling a 9x9 board with the numbers 1 through 9, with each number appearing once and not repeating in each column, row, and 3x3 subgrid. In Ki…
ISEF · 2025
Translational Medical Science
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world, affecting 20 million in the US alone. Retinal Pigment Epithelial (RPE) cells between the reti…
ISEF · 2025
Mathematics
I chose to investigate knot link surfaces in the field of topology/knot theory because it seemed interesting and I saw a similar thing knot surfaces discussed. The question is can a surface…
ISEF · 2025
Physics and Astronomy
The discovery of gravitational waves (GW) has brought about the development of new detectors, including the Laser Interferometer Space Antenna (LISA), which will detect white dwarf (WD) bina…
ISEF · 2025
Plant Sciences
Bioluminescence is a natural phenomenon that enables the emission of light in living organisms and holds great potential in biotechnology. This study evaluated the functionality of an optimi…
ISEF · 2025
Computational Biology and Bioinformatics
Alzheimer's disease (AD) is a complex, progressive neurodegenerative disorder characterized by extracellular Aß plaques, neurofibrillary tau tangles, and neuronal degeneration, involving mul…
ISEF · 2025
Microbiology
Pancreatic cancer remains one of the most lethal diseases, primarily due to its asymptomatic progression and late-stage diagnosis, which severely limits treatment options and reduces surviva…
ISEF · 2025
Behavioral and Social Sciences
In an era where news media significantly shapes public perception, frames societal belief systems, and influences decision-making during responses to public health and global crises, there i…
ISEF · 2025
Biochemistry
Despite being the sixth most fatal cancer worldwide, esophageal cancer is largely overlooked. The high mortality rate of esophageal cancer stems largely from its high metastatic capability.…
ISEF · 2025
Biomedical and Health Sciences
Pancreatic cancer is the second leading cause of death, with 90% of occurrences as Pancreatic ductal adenocarcinoma (PDAC). Currently, Doxorubicin (DOX) is the leading treatment for cancers.…
ISEF · 2025
Cellular and Molecular Biology
Constituting up to 90% of tumor volume in pancreatic ductal adenocarcinoma (PDAC), fibrotic tissue growth (desmoplasia) acts to inhibit chemotherapeutic drug delivery through physical blocka…
ISEF · 2025
Animal Sciences
An owl wing is a mechanical marvel built for silent flight. The posterior margin of each feather has trailing edge fringe which is key to reducing air vortexes resulting in dramatically quie…
ISEF · 2025
Cellular and Molecular Biology
Multiple myeloma (MM) is an incurable cancer of malignant plasma cells with a 5-year survival of 54%. Immunotherapy has recently emerged as a highly promising modality to treat MM. CD8+ T-ce…
ISEF · 2025
Earth and Environmental Sciences
Climate change comes in many forms, sometimes from unexpected sources. Manure management facilities are some of the most overlooked, yet consequential facilitators of climate change, contrib…
ISEF · 2025
Physics and Astronomy
The internal kinematics of massive red supergiant branch (RGB) and oxygen-rich and carbon-rich asymptotic giant branch (AGB) stars in the Magellanic Clouds have been modeled to examine the t…
ISEF · 2025
Robotics and Intelligent Machines
Over the past 5 years, the United States recorded over 25,000 fatal work injuries (AFL-CIO, 2023). Industries like scientific laboratories, recycling and manufacturing facilities are especia…
ISEF · 2025
Biomedical Engineering
The objective of this project is to develop a low-cost, portable, multi-sensor device for accurate early detection of multiple cancers, designed for home use and resource-limited settings. T…
ISEF · 2025
Computational Biology and Bioinformatics
Lung cancer is the most commonly diagnosed cancer worldwide and the leading cause of cancer-related deaths. It is difficult to diagnose accurately, especially at an early stage. No tradition…
ISEF · 2025
Robotics and Intelligent Machines
Lung cancer, the leading cause of cancer-related deaths globally, continues to face limited clinical adoption of machine learning model analysis for diagnosis due to the absence of an integr…
ISEF · 2025
Translational Medical Science
Purpose: Patients with breast cancer (BC) who undergo neoadjuvant therapy (NAT) before surgery and achieve a pathologic complete response (pCR) after NAT have a low rate of recurrence. Howev…
ISEF · 2025
Computational Biology and Bioinformatics
Inflammatory diseases affect billions of patients worldwide. Receptor for Advanced Glycation End products (RAGE) has been identified as a promising target for many inflammatory diseases, inc…
ISEF · 2025
Animal Sciences
Parkinson's disease (PD), the second most common and fastest-growing neurodegenerative disorder affecting over 10 million people worldwide, is characterized by progressive neurodegeneration…
ISEF · 2025
Mathematics
Clinical trials often utilize composite endpoints to provide a comprehensive evaluation of a treatment’s effects by combining multiple related outcomes into a single measure. While tradition…
ISEF · 2025
Biomedical Engineering
One of the biggest hurdles to Stem Cell Therapies' clinical applications has been the difficulty in delivering stem cells safely and retaining them at the target site without migrating uncon…
ISEF · 2025
Earth and Environmental Sciences
The large amounts of CO2 generated by human activities results in an increase in ocean acidity on a global scale (Hill, 2018). The ability to determine long-term open ocean acidification tre…
ISEF · 2025
Mathematics
For the last 20 years, many researchers have explored divisibility properties of integer sequences arising from combinatorial structures. In particular, binomial coefficients have been the s…
ISEF · 2025
Cellular and Molecular Biology
Our project determined that resazurin, a synthetic fluorescing agent originally used as a bioburden detector, is a practical fluorescing agent for quantifying NADH in cell-free reactions. We…