11705 projects whose affiliated fair was here, most recently in 2026.
ISEF records a state or province for some finalists and not others, so these counts do not add up to the country total.
11705 projects · showing 1081–1110
ISEF · 2025
Translational Medical Science
Crohn’s Disease is an autoimmune, inflammatory bowel disorder affecting millions of people globally, characterized by symptoms such as abdominal pain, vomiting, bloating and diarrhea. Curren…
ISEF · 2025
Robotics and Intelligent Machines
Multi-Agent Systems (MAS) have demonstrated exceptional potential in task planning and optimization. However, little research has explored MAS integration across both hardware and software.…
ISEF · 2025
Behavioral and Social Sciences
Recent advances in audio neurofeedback therapy offer a promising solution for individuals with ADHD by training them to self-regulate brain activity, by reducing excess theta waves and enhan…
ISEF · 2025
Biomedical Engineering
Borosins are a family of RiPPs that are characterized by post-translational ?-N-methylations on their peptide sequence. Since ?-N-methylations, though desirable, add difficult synthesis and…
ISEF · 2025
Microbiology
Francisella tularensis, a gram-negative bacterium, is the causative agent of tularemia, a severe zoonotic disease. The CDC classifies F. tularensis as a tier one biothreat agent, as it is hi…
ISEF · 2025
Microbiology
Cutavirus (CuV) belongs to the genus Protoparvovirus, which includes important viruses such as H-1PV, MVMp, and LuIII, known for their applications in cancer therapies and as gene therapy ve…
ISEF · 2025
Plant Sciences
Downy brome (Bromus tectorum) is an invasive annual, cool-season grass that invades disturbed land impacted by overgrazing, fire, drought, and road construction. The application of weed supp…
ISEF · 2025
Materials Science
Biomedical devices for personalized health monitoring are crucial for early disease detection and therapy, yet current devices are rigid and uncomfortable, causing issues with long-term wear…
ISEF · 2025
Computational Biology and Bioinformatics
Obesity-driven inflammation is primarily caused by pro-inflammatory immune cell infiltration, which leads to an increased secretion of pro-inflammatory cytokines like TNF and IL-6. This driv…
ISEF · 2025
Behavioral and Social Sciences
The brain doesn’t always age at the same pace as the rest of the body. Some people's brains stay sharp well into old age, while others show signs of decline decades earlier. Detecting these…
ISEF · 2025
Microbiology
Bacteriophages are viruses that infect bacteria. During infection a phage attaches to a bacterium and proceeds to insert its genetic material into the cell. After that the phage follows one…
ISEF · 2025
Technology Enhances the Arts
Natural Language Processing has led to the development of voice recognition technology, and taking speech analysis further can lead to the development of technology to aid in treatment of sp…
ISEF · 2025
Translational Medical Science
Colorectal cancer is the second leading cause of cancer-related deaths, and early detection is critical. However, traditional pathology is time-consuming, expensive, and dependent on subject…
ISEF · 2025
Technology Enhances the Arts
This project explores a color-to-haptic feedback system designed to assist individuals with visual impairments in perceiving color through touch. A wearable glove equipped with a Red, Blue,…
ISEF · 2025
Microbiology
Chronic inflammation is a significant health concern, damaging tissues and cells, leading to serious diseases like cancer, heart disease, and diabetes. Many anti-inflammatory treatments, suc…
ISEF · 2025
Plant Sciences
Meloidogyne spp., or the root-knot nematode, is the most destructive nematode disease worldwide and persists in threatening the sustainability of the vegetable industry in numerous regions.…
ISEF · 2025
Microbiology
Staphylococcus aureus is a gram-positive pathogenic bacteria that causes community-onset and nosocomial infections, making it a global healthcare threat. Its ability to evade host responses…
ISEF · 2025
Mathematics
This study delves into the computation and classification of combinatorial invariants associated with stable curves in genus 4. The work builds upon Zhang's decomposition formula, emphasizin…
ISEF · 2025
Translational Medical Science
Oral cancer kills over 300,000 lives across the world every year, and oral squamous cell carcinoma (OSCC) is a dominant type of oral cancer. Current diagnosis steps for OSCC typically involv…
ISEF · 2025
Biomedical and Health Sciences
Chimeric Antigen Receptor (CAR) T Cells and Bispecific T Cell Engagers (BiTEs) have revolutionized the treatment of relapsed/refractory hematologic cancers. However, there are no head-to-hea…
ISEF · 2025
Energy: Sustainable Materials and Design
First-generation biofuel crops, like corn and peanuts, are effective for biodiesel production, but compete with food crops and require arable land use. Third-generation biofuels, such as bee…
ISEF · 2025
Chemistry
Antibiotic-resistant bacteria cause over 2 million infections annually in the US, driving the need for new antimicrobials. Zinc oxide nanoparticles (ZnONPs) are a promising solution, but con…
ISEF · 2025
Energy: Sustainable Materials and Design
This science fair project is about Peltier Tiles and Piezoelectric Harvesters and determining which renewable energy source serves as a better source of electricity and applications for both…
ISEF · 2025
Robotics and Intelligent Machines
The citrus industry in Florida has been devastated with multiple diseases - greening, canker, and blackspot - leading to tree death, orchard closure, and lost orange production. Traditional…
ISEF · 2025
Microbiology
Tardigrades are one of the many organisms that have the capability of surviving extreme environments. They do this by going into a stasis known as cryptobiosis including the lack of water kn…
ISEF · 2025
Earth and Environmental Sciences
This project investigated the correlation between solar indices (AE, By, Bz, SYM_H, and F10.7), aurora activity, and TIMt layers. This research was motivated by the findings of Chu et al. 20…
ISEF · 2025
Microbiology
Plant-based natural products are utilized as active ingredients in herbal medicines, and studying their bioactivities is necessary for evaluating their medicinal value. The present study aim…
ISEF · 2025
Translational Medical Science
Malaria is a devastating disease that kills over half a million people annually. Research shows the Plasmodium falciparum protozoan disrupts iron regulation by degrading ferroportin, allowin…
ISEF · 2025
Earth and Environmental Sciences
Surface water is decreasing in the Rio Grande as a consequence of climate change, intensifying the vulnerability of our aquifers due to higher demand for groundwater pumping. Agricultural pr…
ISEF · 2025
Computational Biology and Bioinformatics
This study aimed to identify potential inhibitors of meso-diaminopimelate decarboxylase (LYASE), a bacterial enzyme crucial for lysine biosynthesis, using molecular docking simulations. The…