Lung cancer is the leading cause of cancer related deaths in the world. Despite therapeutic advances, the overall five year survival rate remains low, near 16%. Prediction of patient outcome…
Second Award
Around 1.6 million people die annually from lung cancer--about 3 every minute. The survival time of undiagnosed extended/late stage small cell lung cancer (SCLC), the most fatal lung cancer…
Standard pole straps lead to many thumb injuries. The goal of the project was to redesign the way a strap attaches to a ski pole to prevent injuries caused by the pole strap. Multiple protot…
Biomedical and Health Sciences
Stress is an integral part of daily life and is often portrayed as a negative phenomenon since it causes physical illness as well as cognitive functions deficits. However, not everybody deve…
My project aimed to be able to map an unknown environment and be able to find the shortest path between any two points using a robot. Most robots today have sensors which are reliable enough…
Invasive plants pose a serious threat to ecosystems by displacing and killing native species. Phragmites australis, an invasive wetland reed, has begun to spread vigorously across North Amer…
Prostate cancer metastasis to the bone is predominantly lethal and results from the ability of successful metastatic prostate cancer cells to co-opt microenvironmental cells and processes in…
Purpose The purpose of this experiment is to measure the feasibility and rapid prototyping of printing airfoils using a 3D Printer and then to test the airfoils in a wind tunnel to find the…
Translational Medical Science
Fourth Award
Piezo proteins have been identified as key components of mechanosensitive ion channels in humans and other mammals. These channels are in the early stages of characterization; their mechanis…
The purpose of this project was to investigate how an increase or decrease of the functions of the PI3K p110a isoform affects AID expression to control antibody class switch. Since AID is a…
Biomedical and Health Sciences
Individuals affected by ASD are characterized be a marked different in the ability to communicate and form relationships. New technologies for communication and learning have been used to im…
Fourth Award
Everybody knows that cleaning the oral cavity is good for oral hygiene. However, not everyone knows that during the night sleep, when our mouth doesn’t do saliva flushing, bacteria grows a l…
Biomedical Engineering
Third Award
Lymphatic filariasis (elephantiasis) is a Neglected Tropical Disease caused by the parasitic nematodes Wuchereria and Brugia. Over 120 million people worldwide are infected and more than 1.4…
Third Award
Global carbon dioxide emissions have become one of the most pressing concerns for the world, as the 2015 United Nations Climate Change Conference in Paris suggests; however, global reduction…
Microbeads were found in the Great Lakes and studies show how marine life, such as zooplankton, are mistaking them for food, and how the microbeads are potentially harming them. Organisms ca…
Second Award
Thermotaxis, the directional motion of an organism towards specific temperatures, has been observed in several species of bacteria. Quantitative studies of thermotaxis in bacteria however ha…
Fourth Award
The age of robotics is upon us as we blast through the 21st century, our technology continues to increase exponentially. Rapid advancements in 3D printing is revolutionizing the world of eng…
Coral reefs are a critical part of the ocean’s ecology, being home to 4,000 species of fish and 700 species of coral. Increasing levels of greenhouse gases, notably CO2 , cause acidification…
Translational Medical Science
Allergies are an important health issue in our community. We want to develop a drug to lower the effects of allergies by characterizing the IgE receptor in a mast cell. The mast cell is an i…
Biochemistry
Hardy-Weinberg Equilibrium (HWE), which defines genetic equilibrium in a population, is fundamental for studies in population genetics. Deviations from HWE, or changes in allele frequency in…
This project addresses the issue of increasing drug resistance of pathogenic bacteria in the post-antibiotic era through mathematical and computational analyses. The analyses were focused on…
Third Award
Mutations in the human ACVR1 receptor protein have been proven to cause the degenerative disease Fibrodysplasia Ossificans Progressiva (FOP). To date, in vivo methods of small-molecule drug…
Translational Medical Science
Kava has been used by Pacific Islanders for years. The purpose of this project was to determine which of the Kava metabolites activate THP-1 macrophages to produce pro/anti-inflammatory cyto…
Second Award
The obligate self-pollination aspect in mature Lactuca sativa (lettuce) plants impedes the propagation of traits of commercial interest and makes crossbreeding difficult and tedious. The pur…
Adenosine triphosphate (ATP) provides the chemical energy needed in most biological processes from metabolic reactions to cellular mechanics. ATP consists of an adenine ring, a ribose sugar,…
Energy: Sustainable Materials and Design
Fourth Award
Improper signaling of the nuclear factor-?B (NF-?B) pathway plays a critical role in many inflammatory disease states, including cancer, stroke, and viral infections. Although a majority of…
Electroencephalogram (EEG) machines are often used to diagnose and monitor seizures, brain abnormalities, and sleep disorders, as well as for biofeedback. Versatile personal EEG machines oft…
Translational Medical Science
The purpose of this experiment was to investigate the effects of neuroinflammation and microglial activity on the progression of Alzheimer’s and to develop therapeutics with RNA-Interference…
Translational Medical Science
Fourth Award
Atherosclerosis, a form of cardiovascular disease, accounts for 17.3 million deaths/year(Mozaffarian,2014). Characterized by plaque formation in arteries, it leads to myocardial infarctions…
Steerable needles allow minimally invasive yet precise surgical procedures by reducing the size of incisions and the disturbance of tissues during the operation. Bevel-tipped steerable needl…