11705 projects whose affiliated fair was here, most recently in 2026.
ISEF records a state or province for some finalists and not others, so these counts do not add up to the country total.
11705 projects · showing 5011–5040
ISEF · 2021
Cellular and Molecular Biology Fourth Award
Non-small cell lung carcinoma (NSCLC), accounting for the majority of lung cancer cases, has become a high-studied topic in the field of immunotherapeutics. While there are treatment options…
ISEF · 2021
Biomedical and Health Sciences
Aging is a major contributor towards many diseases. Two examples of these diseases would be Cancer and Alzheimer’s disease, two leading causes of death within America. Aging is a synergy and…
ISEF · 2021
Behavioral and Social Sciences
During the COVID-19 pandemic, adolescents have played a major role in the spread and mitigation of the virus. While adolescents have much lower mortality rates, they are equally prone to con…
ISEF · 2021
Engineering Mechanics First Award
Agricultural irrigation wastage, especially from inefficient infrastructure in developing nations, is among the leading causes of the global water shortage epidemic, which affects an estimat…
ISEF · 2021
Computational Biology and Bioinformatics
Epilepsy is generally diagnosed using electroencephalograms, or EEGs, which detect the electrical activity in a person's brain. Signals recorded from neurological tissue are extremely noisy,…
ISEF · 2021
Robotics and Intelligent Machines
Head and neck squamous cell carcinoma (HNSCC) is a cancer that arises from squamous cells in the head and neck region, a type of cell found in the outer layers of skin and lining various muc…
ISEF · 2021
Robotics and Intelligent Machines
5.5 million Americans have Alzheimer’s Disease(AD), with projected 40% growth by 2030. Only about 25% of the people with AD get diagnosed; even fewer get an early, accurate diagnosis. Early…
ISEF · 2021
Engineering Mechanics
Autonomous Underwater Vehicles (AUVs) are becoming useful tools for maritime researchers due to their cost-effectiveness, low-maintenance, and ability to access dangerous areas. An AUV’s acc…
ISEF · 2021
Plant Sciences
Sustainable agriculture is growing more and more important. Land use is limited and researchers must find ways to grow more crops with less space. Crop leaf angle can have a large effect on…
ISEF · 2021
Engineering Mechanics Third Award
To improve the aerodynamic efficiency of a Formula One (F1) in Schools race car, the original model of the car is evaluated and compared with a new design. The ideas behind the new design ar…
ISEF · 2021
Systems Software
With the advent of quantum computation methods such as Shor’s algorithm to factor large primes, classical encryption protocols are rendered ineffective, necessitating new quantum cryptograph…
ISEF · 2021
Cellular and Molecular Biology
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder for which there is no cure. In 97% of sporadic ALS patients, TDP-43 forms insoluble protein aggregates dysregulating RNA m…
ISEF · 2021
Engineering Mechanics
The Coanda Effect is the tendency of fluid air molecules to remain attached to a convex surface. This effect is utilized on aerofoils, which rely on the attachment of air across the convex s…
ISEF · 2021
Materials Science
More than 4 billion blood tests are performed annually worldwide. State-of-the-art diagnostics requires 7-10 mLs of blood and takes hours to days for results. Drawing mLs of blood for multip…
ISEF · 2021
Environmental Engineering Fourth Award
Our global cargo ship fleet emits 4% of climate change emissions and particulate pollutants, leading to roughly 7.6 million childhood asthma cases, and 150,000 premature deaths annually. A n…
ISEF · 2021
Translational Medical Science Third Award
Parkinson’s Disease (PD), the second most common neurodegenerative disease, is caused by the depletion of dopamine as a result of toxic aggregates formed by a protein called alpha-synuclein…
ISEF · 2021
Computational Biology and Bioinformatics
Recent advances show that the 14-3-3zeta protein is a unique regulator of IL-17A signal transduction. IL-17A signal transduction triggers two, 14-3-3zeta-TRAF5 and 14-3-3zeta-TRAF6-dependent…
ISEF · 2021
Computational Biology and Bioinformatics
Prions, also known as pathogenic neuronal agents, are groups of proteins found clustered in the brain and are responsible for regulatory processes including neuritogenesis, neuronal homeosta…
ISEF · 2021
Engineering Mechanics
On Mars, there must be a method for construction which uses the available resources, a process known as “in situ resource utilization”. While regular concrete is composed of water, aggregate…
ISEF · 2021
Biomedical and Health Sciences Second Award
Cancer immunotherapy has led to vast improvements in long-term survival for patients with cancers like melanoma. However, the low response rate of immune checkpoint blockade (ICB) therapy li…
ISEF · 2021
Biomedical Engineering
Pulmonary embolisms (PE) affect approximately 300,000 to 600,000 people per year in the United States. Between 10 to 30% of those diagnosed with PE die within a month of its detection. As ra…
ISEF · 2021
Systems Software Third Award
The process of registering intra-procedural prostate magnetic resonance images (MRI) with corresponding pre-procedural images improves the accuracy of certain surgeries, such as a prostate b…
ISEF · 2021
Biomedical and Health Sciences
Glioblastoma is a highly aggressive malignant tumor of the central nervous system defined by its inter- and intra-patient heterogeneity. However, understanding of molecular differences withi…
ISEF · 2021
Biochemistry
Iron deficiency anemia is a common occurrence for many, which is caused by low iron levels low Iron absorption. Lactoferrin is a key iron-binding protein and transporter of iron that can hel…
ISEF · 2021
Biomedical and Health Sciences
Alzheimer’s disease (AD) and other related neurodegenerative disorders are some of the most prevalent and debilitating conditions affecting elderly populations. Previous research has indicat…
ISEF · 2021
Physics and Astronomy Second Award
For much of the history of science it has been postulated that the behavior of dynamical systems, such as atmospheric circulation via convection, can be fully predicted once the parts are co…
ISEF · 2021
Behavioral and Social Sciences
The LGBT+ community faces many hardships in today’s society, but one of the less talked about issues is that of internalized oppression. Internalized oppression occurs when a member of a min…
ISEF · 2021
Biomedical and Health Sciences
Aging is associated with metabolic changes in the body as well as adaptations to age-related changes in order to maintain functional mechanisms in the body. An example of a potential compens…
ISEF · 2021
Translational Medical Science
Obesity can weaken the immune system and increase the risk of contracting a plethora of life-threatening diseases. It currently affects 1 in 5 children in the U.S. This study investigated th…
ISEF · 2021
Biomedical and Health Sciences
In the United States, epidemiological studies have highlighted a disparity in cancer incidence and outcome rates between racial groups. This disparity is attributed to numerous factors, incl…