Computational Biology and Bioinformatics
Parkinson's disease is the world's most rapidly growing neurodegenerative disease, and the cause is largely attributed to the misfolding of a protein in the brain known as alpha-synuclein (a…
Earth and Environmental Sciences
Cyanobacterial harmful algal blooms (HABs) pose threats to aquatic ecosystems and public health, yet existing prediction models rely on single-variable correlative thresholds that fail to ca…
Biomedical and Health Sciences
Over 400 million people lack access to basic healthcare globally, with physician-to-patient ratios below 1 per 10,000 in low-resource regions. Language barriers, limited diagnostic infrastru…
Biomedical Engineering
Right Ventricular Endomyocardial Biopsy (RV-EMB) is an invasive procedure where myocardial tissue is obtained for diagnosis of a variety of cardiac conditions. Currently, catheters are large…
Materials Science
Globally, every 1 in 10 babies are born prematurely, their lives dependent on neonatal incubators to maintain a high humidity environment and reduce water loss through their immature skin. H…
Software Design
Evaluating scientific claims requires synthesizing evidence across extensive literature, which is time-consuming for experts and challenging to automate. Existing approaches rely on expensiv…
Environmental Engineering
Biofilms are communities of microorganisms that aggregate and grow on microplastic (MP) surfaces. Bacterial proximity strengthens antibiotic-resistance through the dissemination of antibioti…
Plant Sciences
In 2024, corn losses due to weather and fire events exceeded $3.85 billion in the U.S. alone. Corn is critical for livestock feed, fuel, and trade, but yield variability causes supply instab…
Computational Biology and Bioinformatics
This project’s purpose was to find alternatives to the PET-plastic degrading enzyme ‘PETase’ from vast amounts of existing protein data that function at industrial temperatures (~70°C) for a…
Computational Biology and Bioinformatics
In Alzheimer’s disease, a progressive neurodegenerative disease, a key pathological feature of the is the accumulation of amyloid-ß peptides in the brain, which aggregate to form plaques tha…
Environmental Engineering
Zooplankton are considered keystone species of freshwater ecosystems, but there is still far more research on marine zooplankton than those in fresh water. The lakes and rivers that are home…
Computational Biology and Bioinformatics
A growing body of evidence indicates that P2X7, a homotrimeric ATP-gated ion channel receptor, is a key mediator in neuroinflammatory signaling and cell death pathways in neurodegenerative d…
Environmental Engineering
Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals with strong carbon-fluorine bonds that resist breakdown in the environment and are associated with serious health effects,…
Computational Biology and Bioinformatics
Despite decades of therapeutic development, most disease-associated proteins remain therapeutically inaccessible. These so-called “undruggable” targets typically lack suitable binding pocket…
Technology Enhances the Arts
Over 1 Billion people globally live with mental health conditions driving depression & suicide crises. Music therapy is a proven nonpharmacological approach for emotional regulation, yet acc…
Microbiology
Pseudomonas aeruginosa is prevalent in hospital-acquired pneumonia, with mortality reaching 70%, and chronic cystic fibrosis infections. The reason the anitbiotics don't work is the LasR quo…
Materials Science
Oil spills cause large-scale destruction of marine ecosystems and economies. Current remediation methods primarily rely on mechanical recovery, typically recovering only 2-6% of spilled oil.…
Computational Biology and Bioinformatics
G protein-coupled receptors (GPCRs) are one of the most therapeutically important receptor families, being the target of >30% of FDA-approved drugs. Activating a GPCR changes its shape, allo…
Chemistry
Current organic photovoltaics (OPV) have narrow light absorbance, inefficient electron transport, and low energy output. This project aims to solve these efficiency issues by designing an or…
Physics and Astronomy
Gate-all-around (GAA) transistors are central to the development of next-generation 2 nm-node semiconductor technologies, but their operation is strongly governed by quantum confinement, req…
Chemistry
6PPD is an antiozonant ubiquitously used in global tire manufacturing that reacts with ground-level ozone to form 6PPD-quinone (6PPDQ). 6PPDQ is a compound acutely lethal to coho salmon—a sp…
Earth and Environmental Sciences
Wildfire smoke increasingly impacts agricultural land, specifically in the PNW, yet the effects of seed exposure to smoke remain poorly understood. This study investigated the effects on pla…
Translational Medical Science
Melanoma is the most fatal type of skin cancer, taking over 50,000 lives annually. While advances in checkpoint immunotherapy have decreased mortality rates, it is difficult to determine whi…
Earth and Environmental Sciences
Water treatment plants use disinfectants like chlorine to eliminate waterborne diseases such as cholera and typhoid. However, disinfection results in the formation of disinfection byproducts…
Behavioral and Social Sciences
This project introduces an Artificial intelligence powered web application designed to assist in the early detection of Autism Spectrum Disorder (ASD) through facial expression analysis. Usi…
Computational Biology and Bioinformatics
This study explores the effectiveness of Convolutional Bidirectional Long Short-Term Memory (Conv-Bi-LSTM) in detecting neonatal seizure activity using Electroencephalogram (EEG) data, based…
Translational Medical Science
Diabetes Mellitus is a growing global epidemic, affecting over 500 million people worldwide. The condition is characterized by insulin resistance- failure of body’s cells to respond effectiv…
Computational Biology and Bioinformatics
This study investigated the inhibitory potential of 41 polyprenylated benzophenones (PPBs) from Garcinia species against TEM52 ß-lactamase, aiming to identify a potential non-competitive inh…
Materials Science
Recent efforts in photonic material development have aimed to create high-performance, low-cost components that can be integrated into portable diagnostic systems, especially for use in unde…
Engineering Technology: Statics & Dynamics
Global warming is a significant environmental threat, and vehicles contribute to it greatly. This project not only aims to design a power supply that does not contribute to global warming bu…