189 projects whose affiliated fair was here, most recently in 2026.
ISEF records a state or province for some finalists and not others, so these counts do not add up to the country total.
189 projects · showing 151–180
ISEF · 2016
Age-related macular degeneration (AMD) is ranked as the third major global cause of blindness as reported by the World Health Organization. At present posterior ophthalmic drug delivery proc…
ISEF · 2016
Third Award
The World Health Organization reports that globally over a billion people have some form of disability and between 110 and 190 million have significant limitations in functioning. Worldwide,…
ISEF · 2015
Second Award
Aviation-generated emissions from hydrocarbon fuel combustion account for approximately 3.5% of the world’s greenhouse gas emissions. Current wingtip devices seek to lower induced drag from…
ISEF · 2015
First Award
Recent Influenza, SARS and Ebola epidemics invoke fear of infection among billions of air travelers worldwide. Isolated air in densely packed aircraft cabins propagate disease via direct air…
ISEF · 2015
Biomedical Engineering Second Award
A novel antigen-presenting cell (APC)-targeted immunomodulatory nanoparticle (NP) was developed as a vaccination platform, with potential uses such as cancer therapeutics. The nanoparticle e…
ISEF · 2015
Biomedical Engineering First Award
In this innovative research, a novel oncolytic virus, AM105, is designed to target and selectively kill cancer cells. Current methods of cancer treatment including radiation and chemotherapy…
ISEF · 2015
Fourth Award
H.E.R.O. presents a novel approach towards assisting the visually impaired during navigation through the development of an Arduino platform based, multimodal, haptic feedback device that all…
ISEF · 2015
Translational Medical Science
Huntington’s disease (HD) is an incurable neurodegenerative disorder characterized by physical, behavioral, and cognitive impairments. It is caused by trinucleotide repeat expansions in the…
ISEF · 2015
Biomedical Engineering
Physical activity is an integral part of diabetes rehabilitation. Historically, diabetes rehabilitation has employed low intensity, sustained exercise. Recent studies have demonstrated short…
ISEF · 2015
Governments, businesses, financial institutions and individuals have become reliant upon cryptography and encryption to protect their information. McAfee estimates that the cost of cybercrim…
ISEF · 2015
Systems Software Fourth Award
PURPOSE: To investigate the effect of Leptomycin-B (LMB) on the subcellular distribution of a histone deacetylase protein (HDAC4) in HEK-293 cancer cells and how this response affects kidney…
ISEF · 2015
Systems Software First Award
A rapid, electricity-free cartridge for nucleic acid testing (NAT) from finger-prick blood is proposed to combat the high rate of undiagnosed HIV infection in low-resource settings. The low…
ISEF · 2015
First Award
Hypoxia and heterogeneity in tumor microenvironment is widely recognized as a difficult challenge in conventional cancer therapeutics. Our NanoLab group has verified the use of flagellated m…
ISEF · 2015
Currently, drug interactions are explained by the lock-and-key model which offers a crude approach to quantifying the efficacy of drugs based on receptor communications. There is no gradient…
ISEF · 2015
Systems Software Fourth Award
Type 2 diabetes (T2D) is a chronic disease brought about by metabolic events such as insulin resistance and the progressive dysfunction of insulin-secreting beta cells. Recently, both inflam…
ISEF · 2015
Fourth Award
Experimentation with artificial patination can improve the accuracy of visually identifying prehistoric stone tool source material. Little work exists on identifying patina formation on spec…
ISEF · 2015
Third Award
Annually, over 1.5 million bone grafts occur in the United States, many that are specific to bone allografts. Computer-assisted surgeries leveraging the 3-dimensional (3D) features of graphi…
ISEF · 2015
If the installation of an underwater piping system, a uniquely designed gas engine, and a chamber containing sphagnum moss and methanotrophic bacteria is implemented within a reservoir, we c…
ISEF · 2015
Fourth Award
A considerable amount of potential energy is lost as heat while hot beverages cool down. Until now, no effective technique of recovering this energy has been proposed. Simultaneously, there…
ISEF · 2015
Second Award
Serious injuries and fatalities among cyclists are a problem of global concern. Nationwide studies on cyclist fatality have demonstrated that 92% of cycling fatalities involve a collision wi…
ISEF · 2015
Biomedical Engineering Fourth Award
Chronic lymphedema is a progressive, disabling condition characterized by regional bodily accumulation of protein-rich interstitial fluid. It affects over 100 million worldwide, yet no pharm…
ISEF · 2014
Engineering Mechanics
Water pollution is an important problem that the world is currently facing, where chemical pollutants not only affect the equilibrium of the water source, but also, marine life. The main ins…
ISEF · 2014
Engineering Mechanics Third Award
In 2013 approximately 36 gigatonnes of carbon dioxide was released into the atmosphere – intensifying the greenhouse effect and contributing to global warming and rapid climate change. As de…
ISEF · 2014
Energy: Physical Second Award
A novel, user-worn device (iAid) was devised to help visually impaired people navigate using an Arduino microprocessor and an Android platform. Voice commands were utilized to input the dest…
ISEF · 2014
Mathematics Fourth Award
Clostridium difficile and Methicillin-resistant Staphylococcus aureus (MRSA) have been the main source of nosocomial infections in North America since 2003. There is currently no effective a…
ISEF · 2014
Mathematics
Diabetes is a prevalent disease with serious complications. Current treatment involves repeated daily insulin injections, self monitoring blood tests and dietary management. A novel treatmen…
ISEF · 2014
Mathematics Second Award
Approximately 34 million people worldwide are infected with HIV, including 2.3 million children. To date, there is no accurate point-of-care HIV test for neonates or acutely infected adults.…
ISEF · 2014
Earth and Environmental Sciences
Pest infestation is a major problem for greenhouse growers worldwide. In the United States it is estimated that insect pests damage between 4% and 21% of all crops. In greenhouse settings, y…
ISEF · 2014
Energy: Physical First Award
According to Moore’s law, the number of CPU transistors doubles every 18 months. Increased transistor density causes increased heat production. The need for CPU cooling is therefore increasi…
ISEF · 2014
Environmental Engineering Second Award
Water availability and quality are universally important issues. The imbalance between fresh water demand and supply is expected to worsen. To date, water technology has been focused on desa…