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A Novel Application of Machine Learning Algorithms on Toxin Proteins to Predict Molecular Function

Computational Biology and Bioinformatics

Animal venoms consist of toxin peptides and proteins, and drugs derived from venoms are unique in their ability to interfere with key biological processes in the body, such as blood clotting…

A Novel Application of Microfluidics to Develop a Rapid and Cost-Effective Objective Diagnostic Method for Parkinson's Disease

Biomedical Engineering

Currently, there is no objective diagnostic tool for Parkinson’s disease, a progressive neurological disorder that affects more than ten million people globally. Specialists use visible symp…

A Novel Approach on Mitigating Ocean Acidification by Enhancing Photosynthesis Rate of Macroalgae Ulva lactuca

Earth and Environmental Sciences

Ocean acidification is the evil twin of global warming! When carbon dioxide is absorbed by the ocean, it shifts the pH of the water to neutral. This phenomenon leads to detrimental damage to…

A Novel Approach to Electric Aircraft Engines Using Thorium Dioxide Coated Tungsten Carbide Fins for Thrust Generation

Engineering Technology: Statics & Dynamics Third Award

Currently, long-distance jet engines emit large amounts of carbon dioxide, harming the environment and fueling the effects of climate change. Last year, we proposed an electric design for a…

A Novel Approach to Series Elastic Actuation in Neurorehabilitative Soft Robotics Using Resistance Pressure Sensors to Rotate Servo-Controlled Appendages Accurately

Embedded Systems Fourth Award

Individuals with limited hand motor function after neurological injury are often unable to return to an independent lifestyle, even after rehabilitation. Using flexible PLA (fPLA) and PLA to…

A Novel Approach to Systemic in silico Drug Discovery Using a Machine Learning-Based Prediction of Binding Affinity

Translational Medical Science

Most drugs function by binding to a “target” receptor, activating or inhibiting the “target” signal transduction pathway, which, in ~50% of drug trials, fails to occur, leading to low effica…

A Novel Approach to Treating Parkinson's Disease With Amino Acids to Alleviate LRRK2 Gene Mutation Symptoms in C. elegans Evaluated via the Use of Multidimensional Analysis Methods

Biochemistry Second Award

Parkinson’s disease is a neurological disorder that impacts the movement control of patients due to the degeneration of neurons, reducing the dopaminergic levels in the brain. This causes sy…

A Novel Atmospheric Technosignature Grading System to Optimize the Detection of Extraterrestrial Activity on G-Type Exoplanets Using Next-Generation Space Telescopes

Physics and Astronomy

The detection of Extraterrestrial Intelligence (ETI) holds the potential to greatly expand our understanding of the universe and our place within it. A planetary science-based approach for t…

A Novel Autonomous Vertical Take-Off and Landing Aircraft Using a Variable Thrust Control Vector and Morphing Wing Configuration System

Vertical takeoff and landing (VTOL) of unmanned aerial vehicles (UAV) has many real-world applications, including intelligence, surveillance, reconnaissance, search and rescue, while extendi…

A Novel Autonomous Vertical Take-Off and Landing (VTOL) Aircraft Using a Variable Thrust Control Vector and Morphing Wing Configuration System

Engineering Technology: Statics & Dynamics

Vertical takeoff and landing (VTOL) of unmanned aerial vehicles (UAV) have many real-world aircraft applications, including intelligence, surveillance, reconnaissance, search, and rescue, wh…

A Novel Breast Cancer Recurrence Risk Predictor Using a Deep Learning Multi-omics Data Integration Framework

Computational Biology and Bioinformatics Third Award

Over the last few decades, many breast cancer patients have become disease-free due to the advancements in detection, diagnosis, and treatment. However, cancer can come back for almost 30% o…

A Novel Control System for Autonomous Quadcopter Navigation

Engineering Technology: Statics & Dynamics

Quadcopters have many uses like delivering packages and search-and-rescue, due to easy maneuverability. However autonomous quadcopters are difficult to control since 4 motor inputs control 6…

A Novel Convolutional Neural Network Random Forest Hybrid Model to Aid in the Identification of Tree Species Using Multispectral and LiDAR Data

Robotics and Intelligent Machines

Remote sensing technologies have revolutionized the ability to detect and classify tree species. This is vital for sustainable management and conservation, and especially early detection and…

A Novel CubeSat-Based System for On-Orbit Millimetric Debris Detection and Characterization

Engineering Technology: Statics & Dynamics

Orbital debris are known to pose a severe threat of damage or destruction to orbital assets such as communications satellites and the International Space Station. NASA estimates that there a…

A Novel Electrochemiluminescence Biosensing System Using Photonic Crystal as Luminescence-Enhanced Substrates for the Ultrasensitive Detection of Food-Borne Harmful Substances

Biochemistry First Award

Safeguarding food quality and safety is essential to people's livelihoods. Over recent years, the ingestion of food-borne pathogens and their related metabolic toxins increasingly affects pu…

A Novel Epigenetic Approach for Vascular Elastic Matrix Regeneration: Evaluating the Proteomic Interactions of siRNA-Based Gene Silencing in the EGFR Signaling Pathway of Abdominal Aortic Aneurysms

Cellular and Molecular Biology

Abdominal aortic aneurysms (AAAs) are a life-threatening condition with a ruptured mortality of 80-90% with no current drug-based therapies. They result from the thinning of media & adventit…

A Novel Exosome-Encapsulated-miRNA-Based Machine Learning Model for Blood-Based Diagnosis, Subtype Classification, and Stage Detection of Multiple Cancer Types

Computational Biology and Bioinformatics

By 2040, the global cancer burden will rise to 30 million new cases annually, with the greatest increases affecting low-to-middle-income countries. Current diagnosis methods, such as physica…

A Novel Gait Controller Method for More Stable Operation of Complex Legged Systems

Engineering Technology: Statics & Dynamics

This project presents a novel gait controller method, which generates real-time dynamic responses to efficiently operate complex legged systems. The proposed method uses a stance-swing propo…

A Novel Imaging Technique: Using Fluorescent Dyed Silica Nanoparticles in Identifying Leukemia Biomarkers

Cellular and Molecular Biology

I designed an experiment testing if fluorescent-dyed silica nanoparticles could be used to identify leukemia biomarkers under UV imaging. I hypothesized that if fluorescent-dyed silica nanop…

A Novel Invention of Aerial Delivery of Planting Material for Burnt Forest Restoration Inspired by the Structure of Kadsura coccinea Fruit

Earth and Environmental Sciences Second Award

Wildfires are a crucial problem that greatly affects many living things, especially the loss of many plants and animal species. Over the years, there have been more frequent wildfires. Self-…

A Novel Method in Improving the Accuracy of Exoplanet Classification Using Machine Learning

Physics and Astronomy

Since the Kepler Space Telescope entered service in 2009, the data on exoplanets has increased significantly. Astronomers must manually analyze this data to identify which objects of interes…

A Novel Method of Determining Air Shower Muon Half-Life Using Time of Flight

Physics and Astronomy

Muons are less understood elementary particles that have applications such as interference-proof navigation and structural analysis through tomography. The goal of this project was to find a…

A Novel Non-Invasive Method to Detect Pebrine Disease in Sericulture by Using Phototaxis of Hatched Silkworm (Bombyx mori)

Animal Sciences Second Award

Pebrine disease caused by Nosema bombycis is the most dreaded infectious disease in sericulture practice, accounting for 30% yield loss of silkworm with estimated economic loss of 10 million…

A Novel Passive Positioning System Based on Wave Mechanics

Systems Software

Present-day positioning systems, mainly Global Navigation Satellite Systems (GNSS) and Local Positioning Systems (LPS) have proven useful in many applications. However, they also have some l…

A Novel Phosphosite Localization Approach Using Tandem Phosphoprotein Mass Spectra and Temporal Dilated Networks

Computational Biology and Bioinformatics Fourth Award

Dysregulation of protein phosphorylation during cellular development and signal transduction is associated with a myriad of human cancers, Parkinson’s Disease, and Alzheimer’s Disease. Under…

A Novel Physics Based Predictive Model for Wetland Eutrophication

Earth and Environmental Sciences

Estuaries are wetlands where freshwater from streams mixes with salt water from sea. Also known as “kidneys of our planet”- they are extremely productive environments that filter pollutants,…

A Novel Pneumatically-Actuated Soft Robotic Hand With 3D Vision-Based Teleoperation

Robotics and Intelligent Machines

Having robots at home could help with accomplishing many daily tasks. As larger percentages of the world’s population begin to age, as well as there being many people with disabilities, havi…

A Novel Power-Optimized CMOS sEMG Device With Ultra Low-Noise Integrated With ConvNet (VGG16) for Biomedical Applications

Biomedical Engineering

The needle bio-potential sensors for measuring muscle and brain activity need invasive surgical targeted muscle reinnervation (TMR) and a demanding process to maintain, but surface bio-poten…

A Novel Pre-Hospital Indoor Rescue Drone System for Cardiac Arrest Patient Emergency Assistance and Medication Delivery Through Remote EMS Surveillance

Robotics and Intelligent Machines

Survival chances of out-of-hospital cardiac arrest patients are near zero after 10 minutes, but EMS response rates are on average 9 minutes or longer. This project developed the first indoor…

A Novel Proteomics-Based Model for Determining the Effects of Microplastics on Disease Pathways: Using in silico Machine Learning and in vivo Dugesia dorotocephala Model

Biomedical and Health Sciences

Microplastics pose a significant threat to sustainability for all organisms as they bring toxic chemicals into the ecosystems. In this novel study, public mass spectrometry datasets were sta…