Browse real student projects, abstracts, and awards.
ISEF · 2026
Biomedical and Health Sciences
Protamine 1 (PRM1) and protamine 2 (PRM2) are essential for packaging sperm DNA and maintaining genome stability during spermatogenesis. Changes in their expression levels are associated wit…
ISEF · 2026
Environmental Engineering
This study presents the design, implementation, and validation of a low-cost autonomous water quality monitoring and forecasting system integrating embedded IoT hardware with an adaptive mac…
ISEF · 2026
Computational Biology and Bioinformatics
Agricultural pesticide use remains substantial, increasing chemical exposure, environmental burden, and production costs. U.S. farms spent $21.7 billion on agricultural chemicals in 2024. Be…
ISEF · 2026
Biomedical Engineering
The current nurse to patient ratio in medical-surgical units spans from 1:4 to 1:6, however in long-term care units, this number can range anywhere from 1:15 to 1:30. Additionally, instances…
ISEF · 2026
Computational Biology and Bioinformatics
Enzymes are widely used across healthcare, textiles, and environmental technologies, requiring optimization through enzyme engineering. Traditional approaches rely on wet-lab trial-and-error…
ISEF · 2026
Translational Medical Science
Neurodegenerative diseases, including Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI), are typically diagnosed after 50-80% neuronal loss, reflecting a critical failure of early…
ISEF · 2026
Computational Biology and Bioinformatics
Epilepsy is a neurological disorder characterized by recurrent seizures, and affects nearly 50 million people, causing ~140,000 deaths worldwide annually. Many of these deaths could be preve…
ISEF · 2026
Translational Medical Science
Visual impairment (VI) affects 2.2 billion people worldwide, and 1 billion cases are preventable with early diagnosis. Retinal diseases are preventable causes of VI. Clinical Decision Suppor…
ISEF · 2026
Computational Biology and Bioinformatics
Background: Rupture of cerebral aneurysm, an abnormal bulging of the arterial wall, can lead to brain hemorrhage and stroke. Endovascular surgical treatment is highly invasive and poses sign…
ISEF · 2026
Biomedical Engineering
Respiratory exacerbations are often detected only after symptoms become severe, limiting opportunities for early intervention. Current monitoring systems rely on clinic-based devices or sing…
ISEF · 2026
Biomedical and Health Sciences
Despite advances in immunotherapy, up to 60% of melanoma patients do not respond to treatment. Emerging evidence suggests that physical exercise enhances anti-tumor immunity; however, the mo…
ISEF · 2026
Environmental Engineering
Early wildfire detection and prediction systems based on machine learning have typically relied on a single type of data, either meteorological data or satellite imagery, limiting their accu…
CWSF · 2026
Disease & Illness Gold Medal
Nearly 50% of IVF embryos arrest before they become viable pregnancies, and the molecular mechanisms causing this failure remain poorly understood. The Digital Embryo is the first multi-omic…
ISEF · 2026
Computational Biology and Bioinformatics
Nearly 50% of human IVF embryos arrest before reaching the blastocyst stage, yet the molecular mechanisms causing this failure remain poorly understood. Current literature examines omics in…
ISEF · 2026
Computational Biology and Bioinformatics
Major Depressive Disorder (MDD) negatively affects over 300 million people worldwide as the leading cause of disability, and suicide. Yet, current biomarkers fail to capture its biological h…
ISEF · 2026
Computational Biology and Bioinformatics
Parkinson's disease is the world's most rapidly growing neurodegenerative disease, and the cause is largely attributed to the misfolding of a protein in the brain known as alpha-synuclein (a…
ISEF · 2026
Translational Medical Science
Purpose: About 7.2 million Americans are living with Alzheimer's Disease (AD), with the number expected to to double by 2060. Currently used drugs for AD only reduce disease symptoms and mar…
ISEF · 2026
Chemistry
Industrial wastewaters from gold mining and other industries often contain highly toxic cyanide-based compounds that threaten ecosystems and human health. This project bibliographically inve…
ISEF · 2026
Materials Science
Many advanced technologies, from water purification membranes to battery electrolytes, rely on block copolymers (BCPs) because they can self-assemble into well-defined nanoscale morphologies…
ISEF · 2026
Physics and Astronomy
Dormant black holes (BHs) are believed to be among the most common types of BHs in the Milky Way; despite this, dormant BHs remain largely unstudied due to limitations of current methods of…
ISEF · 2026
Biochemistry
The main feature of cancer is that the cell's normal metabolic process has changed to allow for uncontrolled growth. Monocarboxylate transporter 2 (MCT2, encoded by SLC16A7) is responsible f…
ISEF · 2026
Materials Science
Antimicrobial resistance is expanding at an alarming rate, becoming the greatest global challenge of the 21st century with bacteria developing resistance to some of the best antibiotics and…
ISEF · 2026
Microbiology
Parkinson’s disease (PD) patients primarily receive the drug L-Dopa to replenish the natural stores of dopamine in the body to reduce PD symptoms (Nagatsu 2009). L-Dopa is structurally simil…
ISEF · 2026
Cellular and Molecular Biology
Flavonoids, a subclass of polyphenols, are known for their antioxidant and anti-inflammatory properties, potentially reducing the risk of cancer. This experiment tested the ability of five s…
ISEF · 2026
Biomedical Engineering
Expansion Microscopy (ExM) enhances spatial resolution by physically enlarging tissues, enabling detailed visualization without requiring advanced microscopy systems. ExM has proven effectiv…
ISEF · 2026
Physics and Astronomy
3D printing has the ability to control the internal structure of a product. Published research has not determined the strength-to-weight ratio of infill patterns. The isotropy of infill patt…
ISEF · 2026
Plant Sciences
Approximately 90% of plants have a mutualistic symbiosis with soil fungi, known as a mycorrhizal relationship. The plants and fungi exchange nutrients through the plant's roots. Mycorrhizae…
ISEF · 2026
Animal Sciences
Changes in temperature are known to have molecular effects on biological mechanisms. It has been found that when exposed to heat stress, Caenorhabditis elegans lose fertility and a general d…
ISEF · 2026
Plant Sciences
Before plants can be used as a food source for interplanetary missions, research must be conducted to determine the effects of microgravity on the growth of plants. This experiment was condu…
ISEF · 2026
Microbiology
Restoring severely eutrophic waters, especially in hardened urban river channels, is challenging and costly due to algal blooms, turbidity, microbial overgrowth, oxygen depletion, and nutrie…