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Strophoid Research

Mathematics

To apply the method of inversive generation in order to conclude and prove new properties of a strophoid. And also to find connection of a strophoid with other remarkable curves. Hypothesis:…

Study of the Factors Influencing the Speed of Sound in Low-Pressure Air Based on the Doppler Effect

Physics and Astronomy

This study investigates the properties of the speed of sound (SOS) in low-pressure air through dynamic observations of the Doppler Effect. A sound recorder is mounted on a rotor, which rotat…

Subliminal Messaging in Audio: A Study of the Subconscious

Behavioral and Social Sciences

Subliminal messages are messages passed to the human mind without the mind being consciously aware of it, as, for example, in advertising. To test the efficiency of these messages, teenagers…

Super Battery-Free "HYDRAULIMB" for Hand Amputees

Engineering Mechanics

Most myoelectric prosthetic hands have high dexterity but are heavy in weight due to the large number of built-in electric motors which also have limited battery lifetime. In addition they a…

Superior Antitumor Fusion Proteins Genetically Engineered in Cell-Based Cancer Therapy

Cellular and Molecular Biology

Current cancer therapies face significant challenges, such as inducing adverse patient side effects, having limited access to solid tissue tumours, or failing to target metastatic tumours. A…

Super Tree Glue: An Investigation and Characterization of an Innovative 4-in-1 Combo Material for the Treatment of Tree Infection

Chemistry

In 2018, Super Typhoon Mangkhut left a trail of tree destructions in many Asian cities. Branches of stricken trees were later chopped, resulting in many untreated trees’ cross sections being…

Supervised Machine Learning Algorithm to Predict the Outcome of Shelter Animals

Robotics and Intelligent Machines

Machine learning is the ability for a computer to learn and adapt from experience rather than from code that is already in its program. More specifically, supervised machine learning takes d…

Supplementation of Retinoic Acid on the Regeneration Rate of Dugesia tigrina

Translational Medical Science

Planaria are well known for their phenomenal regeneration abilities. Because of the presence of totipotent stem cells (also known as neoblasts) throughout their body, they are commonly used…

Survival Analysis of Pediatric Neuroblastoma Patients Using Gene Expression Data: Identification of Novel Neural Differentiation Related Biomarkers

Computational Biology and Bioinformatics

Of the over 100 types of cancers that together claim 2,000 lives in the United States daily, neuroblastoma is the most common in children under the age of two. This project seeks to identify…

SWIFT: A Novel Machine-Learning Platform for Space Weather Forecasting from HMI Vector Magnetograms

Physics and Astronomy

Major solar flares (X&M-class) and their resulting Coronal Mass Ejections (CME) and Solar Proton Events (SPE) severely threaten modern human society. A major solar event hitting Earth would…

Synergistic Effect of Combined Heavy Metal Exposure on Dopaminergic Neurodegeneration and Associated Behaviors in C. elegans as a Model for Parkinson's Disease

Microbiology

Neurodegenerative disorders affect more than 6 million people in the United States alone. Heavy metal exposure has been implicated in the progression of disorders such as Parkinson’s Disease…

Synergy Screen of NIH Oncological Drug Set VII in Combination with Aurora Kinase B Inhibitor to Enhance Chemotherapeutic Sensitivity

Translational Medical Science

Small-cell lung cancer (SCLC) is a highly aggressive form of lung cancer. Despite available chemotherapeutics, resistance develops rapidly, accounting for a 6%, 5-year survival rate. Strateg…

Synthesis and Characterization of a Novel PROTAC Containing a Beta Hairpin Sequence Motif

Translational Medical Science

This study developed and characterized a novel proteolysis targeting chimera (PROTAC) incorporating a beta hairpin sequence motif. PROTACs facilitate the proteasomal degradation of ‘undrugga…

Synthesis and Characterization of the Binding of a 5-aminobenzo[c][2,6]naphthyridine-8-Carboxylic Acid and Peptoid Conjugate to Protein Kinase CK2

Biochemistry

The aim of this work was to develop a more effective biligand inhibitor for protein kinase CK2, an effective synthesis for it and characterize its binding ability to CK2. This was accomplish…

Synthesis, Characterization and Application of New 4-Hydroxy-1,3-thiazole Derivatives in Fluorescence Microscopy

Chemistry

Previous research has revealed the strong fluorescence of 4-Hydroxy-1,3-Thiazoles and enabled their various applications. However they have never been tested on their suitability in fluoresc…

Synthesis of Alloy Nanowire Array Electrode for Wearable Direct Urea Fuel Cell

Chemistry

Wearable devices are now very popular and are used widely in health monitoring and sports training. To address the problem of limited battery life of devices, self-powered energy harvesting…

Synthesis of a Novel Flame-retardant Hydrogel for Skin Protection Using Xanthan Gum and Resorcinol Bis(diphenyl phosphate)-coated Starch

Chemistry

Firefighters suffer from burns annually; in 2018, 2835 U.S. firefighters received burn injuries. Existing heat-resistant fabrics have noncontiguous areas, and facemasks are often removed in…

Synthesis of a Tau Aggregation Inhibitor in Relation to Alzheimer’s Disease

A multitargeted approach is suggested to be most effective in inhibiting the formation of tau aggregates in Alzheimer’s disease. Two promising targets for treatment of Alzheimer’s are the in…

Synthesis of Human Urine into Carbon Dots for Implementation as a Visual Arsenic Assay in Water

Arsenic contamination of drinking water poses an acute threat to human health, which is especially compounded in regions with limited resources. Though it is detectable, conventional tests f…

Synthesis of Luminescent Complexes of Lanthanides with New O,N-Tetradentate Ligands

Chemistry

Coordination complexes of lanthanides possess bright luminescence with high quantum yields and long lifetimes. This allows applying them in a variety of fields such as: optoelectronics, cryp…

TaipaEstock: Grain Storage Using Taipa of Hand

Materials Science

One of the problems faced by farmers is the devaluation of their products in the post-harvest period. Bioconstructions for storing agricultural products are sustainable and cheap alternative…

Taking ABiTE out of Cancer: A Novel Aptamer-based BiTE for Cancer Immunotherapy

Biomedical and Health Sciences

Immunotherapy is a treatment in which the body’s immune cells, are stimulated to fight diseases such as cancer. Several immunotherapies have been developed with the aim of helping T Cells ta…

Targeted Breast Cancer Therapy Using Nanoparticles Modified by Tumor-Homing Peptides

Biomedical and Health Sciences

Nanoparticles (NPs) are attractive cancer drugs but cannot target cancer cells, causing side effects in cancer therapy. To tackle this challenge, I developed NPs that could kill breast cance…

Targeted Delivery of Immune Agonists for Antitumoral Response of the Tumor Microenvironment

Materials Science

Tumor-mediated immunosuppression allows tumors to hide from the immune system and avoid recognition. To reverse this suppressive microenvironment, antigen-presenting cells (APCs) and other i…

Targeted Delivery of Immune Agonists for Antitumoral Response of the Tumor Microenvironment

Tumor-mediated immunosuppression allows tumors to hide from the immune system and avoid recognition. To reverse this suppressive microenvironment, antigen-presenting cells (APCs) and other i…

Temperature Distribution Measurement of Transparent Fluids Using Twyman-Green Interferometer

Physics and Astronomy

Temperature field measurement, especially real-time monitoring, has undeniable value in various aspects, but when the field is of uneven gas and high temperature, there’re still imperfection…

Testing a Variety of Methods for Training a Neural Network to Determine Which One Achieves the Lowest Error Rate Fastest?

Robotics and Intelligent Machines

In my project, I wanted to find out what method, out of the ones that I tested, would best train a neural network. Testing these methods is important because neural networks are used on a wi…

Testing Different Anthocyanin Sources and Analyzing the Adsorptions on TiO2 (Titanium oxide) Nanoparticles with an Electron Microscope in DSSC

Energy: Sustainable Materials and Design

Initially, solar cells were made from silicon, but it was very expensive to get. Later on, scientists created dye-sensitized solar cells using ruthenium dye which was a pollutant and it was…

Testing for the Effectiveness of Different Solar Tracker Designs

Central Virginia Governor’s School The purpose of this experiment was to compare the power output capabilities of a prototype single and double axis solar tracker. An artificial light source…

Testing the Activity of Epigallocatechine-3-gallate on Cells of Colorectal Carcinoma in vitro

Biomedical and Health Sciences

The research was aimed at testing the effects of the polyphenolic compound Epigallocatechin-3-gallate on three colorectal cancer cell lines. The effects of this substance have been observed…