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Modeling Neuron Energy Efficiency and Consumption Using Hodgkin-Huxley Equations With Analysis and Application

Computational Biology and Bioinformatics Fourth Award

In the human brain, high amounts of metabolic energy are required to maintain neural activity. A large fraction of this energy is expended in the generation and firing of action potentials,…

Modeling of Amino Acids' Chemical Reactivity Against Cancer

Chemistry Fourth Award

The composition and structure of variable side chains in amino acids determine peptides' unique functions in a wide range of applications. The APD database served as the primary data source…

Modeling of Amino Acids’ Chemical Reactivity Against Cancer

Chemistry of amino acids is incredibly versatile, they are fundamental building blocks, playing a vital function in a variety of bio -chemical processes. They are composed of an amino group…

Modeling the Possible Connection Between the Variation of Homozygous Birc6 Gene and the Premature Ovarian Insufficiency on Zebrafish (Danio rerio)

Cellular and Molecular Biology

200 million of the human population is affected by infertility—a disease that can develop in both men and women due to various reasons—which causes a decrease in the individuals reproductive…

Modelling Lunar Drivetrain Technology Through the Design of a Differential Swerve Drive

Engineering Technology: Statics & Dynamics

This study aimed to develop a differential swerve module which imitated the drivetrain of future NASA Lunar Rovers, effectively exploring the usage of a four-wheeled drive system with two in…

Modelling Paths of the Moon’s Shadow on the Surface of the Earth During Total Solar Eclipses

Physics and Astronomy

Solar eclipses are exciting but short-lived events that rarely occur in populated areas. The astronomy enthusiast might therefore be interested in knowing where they must go to observe some…

Modifying Oncolytic Adenovirus for Osteosarcoma Treatment

Biomedical and Health Sciences

Osteosarcoma, most commonly found in children, originates in the bones and spreads throughout the body over time. Over the last 30 years, the mortality rate for osteosarcoma has not improved…

Modulating Integrin Expression in Pancreatic Tumor Cells

Cellular and Molecular Biology

Pancreatic Ductal Adenocarcinoma (PDAC) is a common type of pancreatic cancer and is characterized by a extremely high mortality rate. PDAC tumors tend to be extremely stiff, the reason for…

Mouseless Mouse: Enhancing Digital Interaction for Individuals With Limited Hand Mobility via Amplify and Smooth Extracted Data From Head Movement Using Real-Time Facial Tracking and Deep Learning

Systems Software Third Award

Individuals with limited hand mobility usually face challenges in daily activities and technology interactions that require fine motor skills and dexterity. To address this issue, innovative…

Mucins as Potential Markers for Disease Progression and Chemotherapy Response in Colorectal Cancer

Computational Biology and Bioinformatics

Colorectal cancer (CRC) represents a major health challenge with significant mortality rates. Due to the difficulties in early intervention, many patients fail to receive optimal therapeutic…

Multi-Functional High-Flux Superhydrophilic/ Supeoleophobic ZnO-Pillared MXene Membrane With Self-Cleaning Properties for Wastewater Treatment

Environmental Engineering Fourth Award

Wastewater is expected to increase by 24% in 2030, posing significant risks to health and the environment. Titanium carbide (2D MXene) membranes offer a potential solution for wastewater tre…

Multilayer Analysis of the Effect of Neighborhood Influence, Socioeconomic Status and Zoning Laws on the Gut Microbiome and Cardiometabolic Health of Native Hawaiian Pacific Islanders on Oahu

Computational Biology and Bioinformatics

Native Hawaiian Pacific Islanders (NHPI) suffer disproportionately from cardiometabolic health conditions compared to other major ethnic groups. This study aimed to address critical gaps in…

Multi-omic Profiling Identifies p63 as a Novel Genetic Determinant Driving Lung Fibrosis and Cancer, Targetable for Treatment

Biomedical and Health Sciences

Lung cancer is the leading cause of cancer-related mortality worldwide. Scleroderma-related interstitial lung disease (SSc-ILD) and lung carcinoma are forms of fibrotic-originating lung dise…

Multi-Scale Knowledge Transfer Convolutional Transformer: A Novel Deep Learning Framework for 3D Brain Vessel Segmentation

Robotics and Intelligent Machines

Recent studies show that small cerebrovascular abnormalities are the cause of many brain disorders. Early diagnosis and monitoring of the abnormalities in vivo at the micro-level facilitates…

Myocardial Infarction Detection System ECG Based That Integrates Signal Processing and Machine Learning for Early Diagnosis

Biomedical Engineering

According to the World Health Organization, The world’s biggest killer is ischaemic heart disease, responsible for 16% of the world’s total deaths. Since 2000, the largest increase in fatali…

NanoFusion: Revolutionizing CRISPR/Cas9 Delivery to MCF-7 Adenocarcinoma via Exosome-Liposome Synergy

Cellular and Molecular Biology

In recent decades CRISPR/Cas9 has emerged as a promising cancer treatment. Using CRISPR knockout plasmid to target the CDK11 cell proliferation gene within cancerous cells could force said c…

National Ground-Level NO2 Predictions via Satellite Imagery Driven Hybrid Neural Networks

Earth and Environmental Sciences Fourth Award

Outdoor air pollution, specifically nitrogen dioxide (NO2), poses a global health risk. Land use regression (LUR) models are widely used to estimate ground-level NO2 concentrations by descri…

Natural Aqua Purifier: A Novel and Sustainable Water Purification Approach Utilizing Natural Coagulants for Easy Implementation in Rural Regions

Environmental Engineering

Access to clean water is one of our most basic human needs, and unsafe drinking water is one of the world's largest health and environmental problems. In 2022, 2.2 billion people globally st…

Natural Eutectogels as a Novel Material for Green Wearable Electronics

Chemistry

The rapidly growing field of wearable electronics faces a critical challenge: the development of materials that are compatible with human tissue. Traditional materials such as hydrogels and…

Nature's Guide to Organ Preservation: The Application of Chrysemys picta Brumation Techniques To Extend the Preservation Period of Organs

Biomedical and Health Sciences

There are currently over 103,000 people on the national transplant waiting list. The kidney has the longest waiting list. Once patients are approved for this treatment there are still many r…

Navigating Demographic Disparities in Louisiana Women’s Health Using Machine Learning Within Geographic Analysis

The issue of women's health in Louisiana is critical, given the state's extremely high maternal mortality rates. Women's health issues disproportionately impact Black and low -income women i…

NeRF Technology: An Economic Approach to 3D Scanning

Robotics and Intelligent Machines

The integration of Neural Radiance Fields (NeRF) technology with 3D scanning systems has significantly advanced the reconstruction of high-fidelity 3D models. In this essay, we explore the h…

Neural Spike Sorting in the Primary Somatosensory Cortex

Biomedical Engineering

The recording of neuronal action potentials from multiple neurons in humans has been a notable advancement for better understanding the nervous system. When our sensory nerves are activated,…

Neuroassist: Cortex -Inspired Meta -Adaptive Synaptic Framework - Revolutionizing AI in Brain - Computer Symbiosis

Current electroencephalogram (EEG) systems suffer from low signal -to-noise ratios and poor spatial resolution, leading to inaccurate diagnosis of neuromuscular degenerative diseases. Moreov…

Neuroevolution of Spiked Neural Networks With HyperNEAT

Robotics and Intelligent Machines

Machine learning and neural networks have seen a rapid increase in popularity over the past few years. Spiked neuron networks (SNN) are a third generation neural network that offer many bene…

NeuroHAT: Democratizing Brain-Wellness Monitoring Developing A Wearable System with fNIRs & EEG Multimodality Classification Engine & Miniaturized Device

Biomedical Engineering

The human brain is one of the most unknown yet essential parts where many life threatening diseases such as strokes, Alzheimer's Disease (AD), and Parkinson's Disease (PD) begin silently. Br…

NeuroHero: A Novel QEEG and HRV Based Neural Network for Explainable Post-Anoxic Coma Prognosis

Biomedical and Health Sciences

Annually, 4.8 million people enter a post-anoxic coma following cardiac arrest, presenting a critical need for early recovery prognosis using Electroencephalogram (EEG) and Electrocardiogram…

Neuropath: Multi-Computational Framework for Developing a Receptor-Based Transcytosis Approach to Facilitate BDNF Transmission for Alzheimer’s Progression Prevention

Computational Biology and Bioinformatics

Affecting 60-70% of the 55 million dementia patients in the world, Alzheimer's Disease (AD) has established itself as one of the most profound neurodegenerative diseases in today's society.…

Neuroprotective Effects of a Combination of Celastrol and Naproxen on Acute Traumatic Brain Injury in a Drosophila melanogaster Model as a Potential Novel Pharmaceutical

Translational Medical Science

Traumatic brain injury (TBI) is the leading cause of death among all traumatic injuries. While there are some treatments, such as nonsteroidal anti-inflammatory drugs (NSAIDs), most cause de…

New Discovery of Conditions for Hydrogen Explosive Combustion in Platinum Foil

Chemistry

When hydrogen is sprayed onto a platinum foil (0.1µm thick), explosive combustion occurs without the use of fire. The reaction principle is postulated to be a surface reaction between hydrog…