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Circulating Chymase and Chronic Kidney Disease: An Analysis of Current Treatments, Demographics, and Clinical Risk Factors

Chronic kidney disease (CKD) results in a progressive loss of kidney function over time, affecting 37 million in the US. Chymase is the primary enzyme mediating angiotensin II formation inde…

CisRF: A Novel Machine Learning Approach to Predict Context Dependent Impacts of Disease Associated Regulatory Elements on Gene Expression

Genome Wide Association Studies have identified 560,000+ Single Nucleotide Polymorphisms (SNPs) associated with disease, most of which are not in protein -coding regions of the genome. Howev…

Classical and Modern Control Theory for Rotor Sail Active Seakeeping

90% of goods move by cargo ships, contributing to 3% of climate change emissions, 7.6 million childhood asthma cases, and 150,000 premature deaths annually. There is a need for climate chang…

CLDN5 Downregulation and Albumin: Investigating Hallmarks of Blood-Brain Barrier Breakdown as Novel Biomarkers of Suicide Neuropathology

Biomedical and Health Sciences

Over 1 million deaths annually can be attributed to suicide, yet no biomarkers exist. This study investigated blood-brain barrier (BBB) disruption by examining claudin-5 (CLDN5) epigenetic a…

Clean Water: Analysis of Interfacial Tension Anionic Surfactant Effects on Evaporative Rate, Molecular Similarity Analysis, and Oil Spill Modeling

Earth and Environmental Sciences

Increasing pollution in large water bodies poses a significant threat to the availability of safe drinking water. As pollutants (surfactants) decrease interfacial tension, when a contaminant…

Clear: Utilizing Glasses-Based Beamformers to Improve Speech Clarity and Spatial Context for the Hearing Impaired

Biomedical Engineering Third Award

Hearing loss is the fourth most prevalent disability worldwide, affecting one in five people, and is correlated with depression, isolation, and decreased life expectancy. Innovation in heari…

CNS-Permeable Glutamate Carboxypeptidase-II (GCPII) Inhibitors as Potential Therapeutics in the Treatment of Traumatic Brain Injury (TBI)

Translational Medical Science

Traumatic Brain Injury (TBI) is an intracranial damage common among soldiers and impact-sport athletes. In severe cases, TBI is associated with neurodegeneration and dementia if left untreat…

Cocoa’s Cognitive Triumph: The Rescue of the Alzheimer’s Model of Drosophila melanogaster With Theobroma cacao Supplementation

Animal Sciences Third Award

Alzheimer's disease, the most prevalent form of dementia affecting over 24 million people worldwide, is characterized by cognitive decline and progressive neurodegeneration; this is mainly d…

COCOTherm: A Simulated Thermal Dataset for Training Wildlife Monitoring Models With Optical to Thermal Image Conversion

Systems Software

COCOTherm addresses the challenges of monitoring wildlife overpasses as part of the I-90 Snoqualmie Pass East Project. The wildlife monitoring program for this project involves 15 networked…

Coding an Algorithmic Day Trading Strategy - Power of 3

Systems Software

Coded stock trading strategies are a fast-growing interest as they can help businesses and individuals not only learn but also make more money while putting themselves at less risk. I decide…

Collision-Free Commutes: Designing a Blind Spot Detection System for Cyclists Using an Ultrasonic Sensor and Computer Vision

Robotics and Intelligent Machines

Riding a bike is a carbon-efficient mode of transportation and a positive way to maintain fitness. However, the inherent difference in speed and size between cars and bikes makes it dangerou…

Colorimetric Smart Packaging System: A Carbohydrate-Based Plastic Alternative for Detecting Food Spoilage

Materials Science

Food safety is one of the most important components of human life. The World Health Organization estimates that foodborne contamination kills 420,000 people per year worldwide. To combat thi…

Combating Huanglongbing Through the Development of a Non-phytotoxic Oxytetracycline Formulation and Novel Fluorescence-Based Detection System

Plant Sciences Fourth Award

Huanglongbing (HLB), more commonly known as citrus greening, is a devastating disease caused by bacteria that colonize tree phloem, restrict nutrient flow, and cause symptoms such as fruit d…

Combating Superbugs: Using Natural Compounds as Down-Regulators of Biofilms Formation in ESKAPE Pathogens (An in silico Study)

Microbiology

Biofilm is the consortia of sessile groups of microbial colonies that adhere on biotic and abiotic surfaces with the help of extracellular polymeric substances (EPS) and glycocalyx. ESKAPE b…

Combating the Drug Epidemic: A Machine-Learning Framework to Predict Novel Drug-Drug Interaction Risks of Illicit Drug Abuse

Computational Biology and Bioinformatics

Each year, the escalating drug epidemic causes over 100,000 deaths in the US. 80% of these mortalities result from multiple drug use toxicity, which yields unpredictable and potentially fata…

Community Support: Connecting In-Need Individuals With Essential Services in South Africa Through an Accessible Instant Messaging Service

Systems Software

The rise of community support platforms has captured the attention of various fields, from leisure to customer support. The existing solutions are often exclusive or add-ons to existing syst…

Comparative Study of Fruit Peel Biopolymer-based Composite Films

As single-use plastic pollution rises, bioplastic from renewable biopolymers offers a sustainable alternative; however, challenges persist in improving their mechanical properties. This stud…

Comparing Different Applications of Indigenous Microorganisms With Synthetic Fertilizer on the Growth of Abelmoschus esculentus (Okra)

Plant Sciences

This study compares the impact of applying Indigenous Microorganisms (IMOs) cultivated through Natural Farming practices (IMO2-5) and the legume Coastal Jack-bean (Canavalia rosea) with synt…

Comparing Metal-Organic Batteries With Lithium, Aluminum and Zinc, Using Bioderived Organic Molecules for More Sustainable Batteries

Energy: Sustainable Materials and Design

Today, the world is transitioning from fossil fuels to renewables, necessitating energy storage due to the intermittent nature of these new sources. To address this issue, we turned to natur…

Comparing the Eddy Current Generation Between North -South Array and Halbach Array for Magnetic Induction Heating Element

This project aims to use an eddy current generator using a Halbach array to create a sustainable heating element for water desalination and test the effectiveness of a north-south array vers…

Comparing the Functional Capacity and Transcriptional Profiles of Chimeric Antigen Receptor (CAR) T Cells and Bispecific T Cell Engagers (BiTEs)

Biomedical and Health Sciences

Chimeric Antigen Receptor (CAR) T cells and Bispecific T cell Engagers (BiTEs) are two novel immunotherapy platforms. I hypothesized that the different mechanisms used by anti-CD3-CD19 BiTEs…

Comparing the Success Rate for Acropora palmata (Elkhorn Coral) Outplanting between Local Volunteers and NOAA Marine Biologists in Puerto Rico

Elkhorn coral, Acropora palmata is a threatened species in the Caribbean. The degradation of the A. palmata population stimulated rehabilitation initiatives. This study analyzed the survivor…

Comparison of Brain Waves, Blinking, and Reading Comprehension When Reading on an Electronic Device and a Printed Text

Behavioral and Social Sciences

Technology dependency is increasing; estimations say 97% of Americans own a smartphone (Pew Research 2024); therefore, it is important to know how it affects society. This project aimed to d…

Comparison of Quantitative PCR and Metabarcoding Methods for the Enumeration of Sockeye Salmon Using Environmental DNA: Year 2 of an Ongoing Study

Earth and Environmental Sciences Fourth Award

Planetary biodiversity is declining at alarming rates. Species conservation depends on knowing what species are present in an environment and in what quantities. A keystone species in Alaska…

Comparison of the Spiral Wave on the Fabric and the Gravitational Wave From the Orbiting Binary

Physics and Astronomy Fourth Award

Gravitational waves are caused by fluctuations in the curvature of spacetime from Einstein's general theory of relativity. When black holes or objects with high mass orbit each other or coll…

Comprehensive in vitro and in vivo Evaluation of Antidiabetic, Antifungal, Antioxidant, Larvicidal, Bioelectricity and Anticancer Activity of Six Native Plant Species: Innovations for Novel Drug Discovery

Microbiology Fourth Award

Plant-based natural products are utilized as active ingredients in herbal medicines, and studying their bioactivities leads to better understanding of their possible medicinal value. The pre…

Computational Assessment of Apigenin as a Prospective Protein-Based Therapeutic Targeting Mucin-1

Computational Biology and Bioinformatics

Mucin-1 MUC1 is a high molecular weight glycoprotein that can overexpress, causing various cancers and playing a significant role in tumor progression and metastasis. Developing targeted the…

Concentration-Dependent Effects of Dietary Niacin and NAD+ in Longevity, Memory, and Motor Function of Drosophila melanogaster

Animal Sciences

Niacin is an essential nutrient for life. It serves as a precursor to nicotinamide adenine dinucleotide (NAD+), a critical coenzyme for ATP production, DNA repair and gene expression. In hum…

ConnectBreathe: Multiplatform Biomedical System for Respiratory Physiotherapy With Gametherapy

Biomedical Engineering

According to the WHO, respiratory diseases are among the leading causes of mortality, and collectively, over one billion people suffer from acute or chronic respiratory conditions worldwide.…

Continuous Hemodynamics Monitor: Novel Smart Sensor for Real-Time Postoperative Cardiac Care

Embedded Systems Third Award

Importance: Decompensated heart failure causes 3 million rehospitalizations. This is a result of current ineffective and inaccessible cardiac monitoring standards, which rely on symptoms tha…