In recent years, generative machine learning algorithms have been successful in designing innovative drug- like molecules. SMILES is a sequence -like language used in most effective drug des…
The use of biodegradable plastics is becoming more and more widespread, and this project’s aim is to depolymerize manufactured PLA products in order to obtain reusable polylactic acid. Zinc…
Mrs. Linda Correa, UPRP The demand for prostheses for animals is still low, mainly due to the cost involved. A prosthesis is a device designed to replace a body part. These devices can be us…
The purpose of this study was to design a trap that would be used to track whether or not crabs during their megalopa stage had a settlement preference. Knowing their settlement preferences…
Huntington’s Disease (HD) is a fatal neurodegenerative disorder caused by a mutation in the huntingtin gene (HTT). This abnormal sequence codes for a mutated version of the huntingtin protei…
General purpose humanoid robots have long been envisioned for a plethora of applications such as disaster relief, industrial automation, agriculture, or elderly assistance. A humanoid form f…
The Raspas Complex in Ecuador, estimated to be approximately 120+ Ma old, is a metamorphic fossil subduction zone with diverse rock types including eclogites. This study determines the preci…
Type 1 diabetes (T1D) is an autoimmune disease that leads to destruction of insulin producing 𝛽-cells. It is unknown what causes the disease and there’s no lasting cure. The protein tyrosine…
There is an alarming increase in the population of ticks and tick-borne diseases (TBDs), with 475,000 cases reported annually, some of which are fatal (Kugeler et al., 2021). Due to limited…
As we enter an era where natural disasters are increasing in frequency and intensity globally, the need for advanced disaster response technologies has never been more pressing. Floods, in p…
Across neurological drug development, researchers struggle with the high selectivity of the blood -brain barrier (BBB), where most drugs are unable to pass from the blood into the brain. As…
Scaffold/MatrixAttachment Regions (S/MARs) are specific regions of DNA that help to stabilize chromatin structure and regulate gene expression by facilitating interactions between DNA and th…
UGT1A1 is an enzyme involved in metabolizing Irinotecan, a DNA topoisomerase class I inhibitor chemotherapeutic drug. Polymorphisms within the UGT1A1 gene promoter reduce UGT1A1 mRNA express…
Artificial insemination relies on viable semen, the maintenance of which in the swine industry is a challenge due to the gradual decline in sperm quality during chilled storage. Previous stu…
To combat rising mortality due to cancer, it is necessary to develop early diagnostic techniques for the rapid identification of cancer before metastasis. Triple negative breast cancer (TNBC…
This study investigates Potato Virus Y (PVY) in potato crops, a virus that significantly impacts yields for farmers nationwide. PVY is an infectious virus transmitted from plant to plant thr…
Research Ampicillin and amoxicillin are two highly impactful penicillin antibiotics utilized to treat neonatal sepsis and other widespread diseases, improving the health of millions of young…
Several studies have shown that hydroelectric generation systems using an undershot water wheel can reach an efficiency of around 65%; however, making these generation systems out of Fused D…
Gastroparesis, characterized by slowed or absent gastric contractions, affects 1.8% of the population, presents with severe nausea, abdominal pain, a high mortality rate, and incurs high tre…
Arkansas for Medical Sciences A high incidence of hepatorenal impairment in cancer patients treated with cisplatin has been reported. Berberine, a plant alkaloid possesses wide range of medi…
This study examines the effects of trust in the patient -doctor relationship and the physician's empathetic approach on patient satisfaction. It proposes two hypotheses: first, there is a di…
Helmets are designed to protect against severe Traumatic Brain Injury (TBI). TBI can be prevented through impact force dissipation over a larger surface area, cranial deceleration over a len…
As global electricity demand increases, the majority of power is produced by thermoelectric plants using fossil and nuclear fuels, despite the rising role of renewables like solar and wind.…
Zero-knowledge rollups (ZKR), the best scalability solution for the cryptocurrency Ethereum, processes thousands of Ethereum transactions in a batch and uses zk -SNARKs (zero -knowledge succ…
Cancer is the second leading cause of death, behind heart disease, with chemotherapy as one of the primary forms of treatment. As a result, researchers are turning to drug combination therap…
Background: Myocardial ischemia-reperfusion (I/R) injury, a critical cardiac complication, is characterized by an excessive generation of reactive oxygen species (ROS) during heart reoxygena…
Aerodynamic drag and downforce are key factors in automotive design. To decrease drag and increase downforce, novel solutions are created and fluid flow around the vehicles’ bodies is analyz…
One in three people are affected by metabolic disorders including obesity, high cholesterol, and high blood pressure, leading to increased risk of stroke, diabetes, and heart disease. The st…
The deployment of autonomous vehicles (AVs) is rapidly expanding to numerous cities. At the heart of AVs, the object detection module assumes a paramount role, directly influencing all downs…
Arctic sea ice plays integral roles in both polar and global environmental systems, notably ecosystems, communities, and economies. As sea ice continues to decline due to climate change, it…