Browse real student projects, abstracts, and awards.
ISEF · 2025
Environmental Engineering
Microplastics persist in the environment, move across the food chain, and are easily ingested because of their tiny sizes, harming aquatic organisms and posing health risks to humans. As par…
ISEF · 2025
Biomedical Engineering
Diabetic foot ulcers (DFUs) are a major cause of lower-limb amputations, with over 160,000 diabetics in the United States undergoing amputations annually. This project presents an AI-powered…
ISEF · 2025
Biomedical Engineering
Musculoskeletal and neurological conditions are the biggest drivers of disability & illness. Currently, physicians diagnose them by triangulating possible biomarkers and multiple abnormaliti…
ISEF · 2025
Biomedical and Health Sciences
Congenital heart defects (CHDs) refer to structural defects in the heart that are present at birth. Hypoplastic Left Heart Syndrome (HLHS) is the most complex CHD and occurs when the left si…
ISEF · 2025
Microbiology
Before the discovery of antibiotics, bacterial infections constituted a leading cause of human mortality. Antibiotics used during World War One and the subsequent introduction of penicillin…
ISEF · 2025
Robotics and Intelligent Machines
The growing evolution of artificial intelligence tools has culminated in the development of potentially harmful technologies, such as audio deepfakes. These artificially created media can cl…
ISEF · 2025
Animal Sciences
Artificial lighting significantly reduces insect populations, contributing to their mass extinction alongside habitat loss, pollution, invasions, and climate change. This project aims to dev…
ISEF · 2025
Plant Sciences
As of 2024, micronutrient deficiency cases are increasing throughout the world. To counter this, my experiment aimed to improve micronutrient availability in barley low-phytic acid (lpa) mut…
ISEF · 2025
Translational Medical Science
Rheumatoid Arthritis (RA) is an autoimmune arthropathy that affects over 18 million people globally, causing immense joint pain and swelling. Current treatments (e.g., methotrexate, adalimum…
ISEF · 2025
Cellular and Molecular Biology
Alzheimer’s disease (AD), a neurodegenerative disorder causing cognitive deterioration, remains a leading cause of death. Previous research has not fully clarified the impact of amyloid-beta…
ISEF · 2025
Environmental Engineering
As the potential of microalgae as a resource becomes increasingly recognized, this study explored foam flotation as a means to extract it from an aqueous environment. A small-scale column fl…
ISEF · 2025
Technology Enhances the Arts
Sign language serves as the main means of communication for the Deaf and Hard-of-Hearing community, yet barriers persist for non-signers who either lack the practical exposure to master it o…
ISEF · 2025
Computational Biology and Bioinformatics
Carcinogenicity assessment is vital in public health and regulatory compliance in multiple industries. In vivo bioassays are costly and time-consuming, while in vitro assays can be simplisti…
ISEF · 2025
Cellular and Molecular Biology
Environmental changes, including rising atmospheric carbon dioxide levels and increasing ozone pollution, continue to alter Earth's atmosphere. Ozone layer depletion leads to increased level…
ISEF · 2025
Computational Biology and Bioinformatics
Protocadherins (pcdhs) are responsible for the formation of cell to cell adhesion proteins, which makes them crucial to neural development and function. Clustered protocadherins are a type o…
ISEF · 2025
Biomedical and Health Sciences
Inflammation is the body's natural response to combat infections, allergies, or injuries. The most commonly available treatments—non-steroidal anti-inflammatory drugs (NSAIDs) and corticoste…
ISEF · 2025
Behavioral and Social Sciences
elf-cognition, or the perception of one’s thoughts and identity, plays a fundamental role in cognitive processes such as memory, attention, and decision-making. Psychological and neuroscient…
ISEF · 2025
Environmental Engineering
Water pollution is a global issue, with sources ranging from industrialization and agricultural activities, to natural disasters like wildfires. These fires are especially concerning as they…
ISEF · 2025
Environmental Engineering
According to the World Health Organization (WHO), air pollution is responsible for around 7 million premature deaths each year. It remains a major risk to human health, especially in urban a…
ISEF · 2025
Translational Medical Science
Commonly known as the yellow water lily root or kaandoosh in Ojibwe language, the rhizome of Nuphar advena is utilized by Indigenous communities for treating a wide variety of ailments, incl…
ISEF · 2025
Environmental Engineering
Heavy metal contamination in coastal ecosystems, such as the southern shores of Oahu, poses critical ecological risks. This study explores the potential of Aiptasia anemones for bioremediati…
ISEF · 2025
Behavioral and Social Sciences
Geriatric populations living with Alzheimer’s disease often experience low mood levels that can exacerbate their symptoms and shorten their life spans. The most common treatments for these l…
ISEF · 2025
Earth and Environmental Sciences
Coronal Mass Ejections alter space weather, causing geomagnetic storms, atmospheric density disruptions, and ionospheric turbulence, damaging over 2 trillion dollars of satellites and power…
ISEF · 2025
Cellular and Molecular Biology
Perfluorooctanesulfonic Acid (PFOS) and Perfluorooctanoic Acid (PFOA), known as “forever chemicals,” are persistent environmental pollutants associated with many diseases, including cancer.…
ISEF · 2025
Animal Sciences
Fall armyworms damage over 80 host plants, especially maize, and cause annual crop losses of around $9.4 billion. With the global population projected to reach 9 billion people by 2050, the…
ISEF · 2025
Biomedical Engineering
Robotic-assisted minimally invasive surgery (RAMIS) was used in millions of procedures in 2024. Despite its widespread use, it overwhelmingly lacks force sensing. Few systems offer this feat…
ISEF · 2025
Translational Medical Science
Stroke, the fifth leading cause of death and a major cause of disability in the US, is a time-critical emergency handled by EMS agencies—20% of which manage 80% of service calls (Krohmer & E…
ISEF · 2025
Biomedical Engineering
As of 2017 it is estimated that nearly 57.7 million people have amputations, and this number is expected to double by 2050. Within the U.S. it is reported that 34% of amputations are upper e…
ISEF · 2025
Computational Biology and Bioinformatics
Immunohistochemistry is a popular method for diagnosing diseases like cancer. To make a diagnosis, pathologists manually analyze every cell in a tissue sample, which is time-consuming and pr…
ISEF · 2025
Materials Science
During space travel, space craft and the astronauts within are exposed to galactic cosmic rays; prolonged periods of exposure to these rays can cause cancer, injuries to the nervous system,…