Browse real student projects, abstracts, and awards.
ISEF · 2025
Translational Medical Science
Cancer is currently the second leading cause of death in the world. There are several treatments available, but most have side effects or are highly expensive. Therefore, it is necessary to…
ISEF · 2025
Animal Sciences
The presence of microplastics in the human body has been recently discovered, but little is known about whether they can cause harm to bodily systems. This experiment uses C. Elegans as a ba…
ISEF · 2025
Biomedical and Health Sciences
Nicotine is a highly addictive drug that has been found to disrupt gamma aminobutyric acid (GABA) neuron migration in the developing cerebral cortex. This project investigates if GABA neuron…
ISEF · 2025
Physics and Astronomy
The aerodynamic efficiency of a rocket is significantly influenced by the geometry of its nose cone. The shape of the nose cone directly affects drag, a resistive force that opposes motion a…
ISEF · 2025
Materials Science
According to the Global Energy Perspective published by McKinsey in 2024, global electrical energy demand is expected to triple by 2050. This dramatic increase in electrical usage cannot be…
ISEF · 2025
Physics and Astronomy
The size of the powder grains significantly affects the accuracy and speed of a .44 Magnum cartridge. Finer powders burn more evenly and quickly, resulting in higher muzzle velocity and fast…
ISEF · 2025
Translational Medical Science
Leukemia, a cancer of blood-forming tissues, is the 10th most common cancer. This study focused on the impact that cannabinoids (CBD) and nicotine had on the growth rate of K562 cell lines.…
ISEF · 2025
Biomedical and Health Sciences
Sleep is a critical physiological process necessary for cognitive function, emotional stability, and brain health. However, both acute and chronic sleep deprivation significantly impair brai…
ISEF · 2025
Animal Sciences
This study was performed to increase awareness of the potential risks of high levels of nitrates. My goal was to determine how sodium nitrate affects the model organism Caenorhabditis elegan…
ISEF · 2025
Biomedical and Health Sciences
Pediatric sarcomas comprise approximately 10% of childhood solid tumors, with metastatic disease yielding survival rates as low as 20-25%. Despite many efforts, advancements in survival outc…
ISEF · 2025
Translational Medical Science
Background: Parkinson’s disease (PD) is a neurodegenerative disease caused by degeneration of dopaminergic neurons due to alpha-synuclein (AS) aggregation. Microbiome dysbiosis has been reco…
ISEF · 2025
Plant Sciences
Aquaponics is a form of agriculture that involves plant and marine life. In an aquaponics system, the fish provide essential nutrients to the plants and in return the plants clean the water…
ISEF · 2025
Earth and Environmental Sciences
My project focused on the effect of fire mitigation on avian biodiversity as measured through bioacoustics, to ultimately understand forest health. It was inspired by the controversy that oc…
ISEF · 2025
Materials Science
As plastic pollution worsens, companies have begun searching for green plastics that last long but degrade naturally. Natural fiber composites, when paired with biodegradable resins like epo…
ISEF · 2025
Energy: Sustainable Materials and Design
This project explores how piezoelectricity in electric vehicle tires can generate energy and how different road conditions impact output. Climate change is an ongoing issue, and piezoelectri…
ISEF · 2025
Biomedical and Health Sciences
This study aims to understand how the increase in pH levels within the stomach, caused by a condition called Hypochlorhydria, contribute to a decrease in the ability to digest food and absor…
ISEF · 2025
Earth and Environmental Sciences
Acres burned by U.S wildfires have increased since the 1980s, due to warmer temperatures. Over 7 million acres have burned per year in the past 20 years (NOAA). Wildfire plays an integral ro…
ISEF · 2025
Computational Biology and Bioinformatics
While it is a relatively well-researched cancer therapy study, the difference in efficacy between lycopene isomers has not been explored. This carotenoid is mainly utilized for its antioxida…
ISEF · 2025
Biomedical and Health Sciences
The use of antibiotics to inhibit breast cancer cell proliferation is a novel approach to cancer treatment. Antibiotics, such as gentamicin and chloramphenicol, primarily known for their ant…
ISEF · 2025
Plant Sciences
Ayurvedic medicine is a natural way to support the immune system and relieve allergy symptoms. This study explores Ayurvedic remedies, particularly turmeric, in modulating immune response an…
ISEF · 2025
Physics and Astronomy
Previously, the Hadamard Random Walk was shown as a viable way for representing the maximum-likelihood estimate of the semantic fluency task, an important metric for assessing the semantic m…
ISEF · 2025
Systems Software
Computers are everywhere today, and digital traces often remain that can help reconstruct past events. When available, computer forensic artifacts can be crucial in establishing guilt or inn…
ISEF · 2025
Behavioral and Social Sciences
Marginalization of historically disadvantaged communities manifests in academia through inequitable funding structures. Scientists identifying as members of minority groups face greater diff…
ISEF · 2025
Biomedical Engineering
Breast cancer is the most common cancer in women worldwide, yet its death rate is decreasing because of advancements in early detection. Although current imaging systems like mammograms, ult…
ISEF · 2025
Computational Biology and Bioinformatics
Systemic Lupus Erythematosus (SLE) is a complex chronic autoimmune disease characterized by widespread inflammation and tissue damage. Its multifactorial etiology, involving a variety of env…
ISEF · 2025
Biomedical Engineering
Over 462 million individuals suffer from Type II Diabetes worldwide. However, current glucose monitors are painful, costly, and unsustainable. This project establishes a novel, non-invasive…
ISEF · 2025
Environmental Engineering
Guava seeds, often discarded as waste during fruit processing, represent a significant untapped resource. In 2023, Egypt produced over 363,000 tons of guava, resulting in approximately 54,00…
ISEF · 2025
Energy: Sustainable Materials and Design
"Harmony" suggests that the device does not only disconnect electricity, but also promotes the idea of integration and harmony between technology and protection. It is as if your device is p…
ISEF · 2025
Behavioral and Social Sciences
The purpose of this research was to determine how different types of puzzles—Sudoku and jigsaw puzzles—affect memory retention and concentration, and whether engaging in both leads to greate…
ISEF · 2025
Biomedical and Health Sciences
The purpose of this project was to determine if increased hypohydration of a sheep brain is directly correlated with brain tissue damage after exposure to a concussion-inducing force. The hy…