Browse real student projects, abstracts, and awards.
ISEF · 2025
Chemistry
Light is a promising alternative to traditional reagents for synthesis due to its reduced environmental toxicity, ease of control, and lowered cost. Moreover, photochemisty’s ability to crea…
ISEF · 2025
Computational Biology and Bioinformatics
Alzheimer’s disease (AD) affects 1 in 9 individuals aged 65+ in the U.S., with females twice as likely as males. As AD pathology begins decades before symptoms appear, early detection and in…
ISEF · 2025
Materials Science
Over 40% of chemotherapy patients suffer toxic side effects due to non-specific targeting, and most genetic therapies are prematurely degraded before they can reach target organs, limiting t…
ISEF · 2025
Systems Software
A fractal is a mathematical object with non-integer dimensions, characterized by self-similar patterns repeating at different scales. They help describe intricate natural phenomena, like the…
ISEF · 2025
Environmental Engineering
With rising carbon dioxide (CO2) emissions accelerating climate change, carbon capture technologies have become essential. Cryogenic carbon capture (CCC) leverages low temperatures to separa…
ISEF · 2025
Chemistry
In our research we focused on antivirotics, broad-spectrum drugs against RNA viral diseases. Galidesivir, a molecule that today appears to be the most optimal inhibitor of viral RdRp, became…
ISEF · 2025
Computational Biology and Bioinformatics
This project investigates the genetic mechanisms underlying Alzheimer's Disease (AD) and Limbic-Predominant Age-Related TDP-43 Encephalopathy (LATE) and their co-occurrence by analyzing diff…
ISEF · 2025
Physics and Astronomy
Flexible two-dimensional (2D) field-effect transistors (FETs) have gathered great interest, due to the need to solve scalability problems that are commonplace in 3D FETs. Specifically, the r…
ISEF · 2025
Biomedical and Health Sciences
Cardiovascular disease (CVD) causes 20.5 million deaths annually and imposes significant economic burdens due to rising healthcare costs. While pharmacological treatments and surgeries are t…
ISEF · 2025
Embedded Systems
Despite technological advancements in automation, the construction industry continues to primarily rely on manual labor. This project strives to implement autonomous masonry utilizing drones…
ISEF · 2025
Robotics and Intelligent Machines
The electricity demand for large language models (LLMs) has dramatically increased, driven by their intensive computational needs. Optimized Arithmetic via Ternary Networks (OATNet) is propo…
ISEF · 2025
Physics and Astronomy
Asteroid observation is vital for gathering lightcurve data, enabling the refinement of asteroid models, reconstruction of their three-dimensional shapes, and derivation of astrophysical pro…
ISEF · 2025
Behavioral and Social Sciences
Lacking adequate tools for early detection and treatment of Oppositional Defiant Disorder (ODD) and Conduct Disorder (CD) among Egyptian children and adolescents poses a crucial challenge. A…
ISEF · 2025
Mathematics
Purpose In this study, Rowlands' sequence, a recursive sequence discovered in 2003, was studied. The aim was to develop a conditional proof of: Conjecture 1: The first difference of Rowlands…
ISEF · 2025
Mathematics
This research looks to define a basis and the behavior of the Tau-divisor topology. This can be viewed as a permutation of the usual divisor topology by implementing the Tau-factorization th…
ISEF · 2025
Translational Medical Science
Cancer is the second leading cause of death worldwide, affecting 20 million people and being responsible for >9.7 million deaths annually. Early prediction of clinical outcomes is crucial fo…
ISEF · 2025
Biochemistry
At-home blood collection, such as the dried blood spots for fertility workups has been challenging due to low circulating Anti-Mullerian Hormone (AMH) concentrations and dependence on traine…
ISEF · 2025
Earth and Environmental Sciences
Heavy metal contamination in water poses a significant threat to human health and the environment. Effective detection of heavy metals is crucial for the prompt removal of contamination sour…
ISEF · 2025
Biomedical and Health Sciences
The study analyzed the antioxidant content in teas, coffees, red wines, and various fruits. The biological effect of antoxidants includes antibacterial, antiviral, anti-inflammatory, antiall…
ISEF · 2025
Biomedical Engineering
Organ-on-a-Chip (OOC) devices have the potential to revolutionize drug testing as an ethical, in vitro alternative to traditional methods. However, further research and adoption is limited b…
ISEF · 2025
Energy: Sustainable Materials and Design
This project explores the design, construction, and optimization of a 3D-printed impulse turbine using compressed air for electricity generation, to reduce intermittency in renewable energy…
ISEF · 2025
Energy: Sustainable Materials and Design
Microbial fuel cell (MFC) technology is gaining interest in the scientific community as a promising alternative energy source. However, current MFCs have several limitations. Therefore, this…
ISEF · 2025
Translational Medical Science
Osteoarthritis (OA) is a chronic inflammatory joint disease affecting over 500 million people, leading to cartilage degeneration and severe pain. Current treatments are invasive, costly, and…
ISEF · 2025
Engineering Technology: Statics & Dynamics
Space debris cleaning has yet to see a viable solution that would effectively remove debris while staying in good condition. Of the active methods of debris removal proposed, tether nets hav…
ISEF · 2025
Biochemistry
Ionizable lipid nanoparticles (LNPs) are the mainstream delivery mechanisms for mRNA therapeutics. pH-sensitive protonation allows their membranes to favorably (de)stabilize based on the sur…
ISEF · 2025
Behavioral and Social Sciences
Academic burnout is currently a very widespread issue that is affecting students all over the world. This project analyzed the correlation between academic burnout and emotional intelligence…
ISEF · 2025
Earth and Environmental Sciences
In 2024, over 10,000 tons of oil were spilled into the ocean, damaging the environment and costing billions of dollars in mitigation efforts. This project is a continuation of previous resea…
ISEF · 2025
Materials Science
Purpose: Conventional paints pose significant health and environmental hazards due to heavy metal presence and volatile organic compound emissions, necessitating safer alternatives. I previo…
ISEF · 2025
Chemistry
Over 350 million tons of plastic waste are produced annually while less than 10% is recycled. Through catalytic hydrogenolysis, plastic waste can be converted into diesel with strontium tita…
ISEF · 2025
Biomedical and Health Sciences
Researcher's acquaintance has ADHD and takes Adderall and shared that its effect (attention improvement) reaches a peak and drops quickly, resulting in having to time pill’s intake with upco…