Browse real student projects, abstracts, and awards.
ISEF · 2025
Plant Sciences
Coffee and tea are among the world's most popular drinks, containing large quantities of caffeine, a central nervous system stimulant. Many plants have been shown to produce caffeine by usin…
ISEF · 2025
Animal Sciences
Hector’s lantern fish (Lampanyctodes hectoris), a common mesopelagic species along the west coast, is known to be parasitized by the copepod Cardiodectes bellotti, which consumes its host’s…
ISEF · 2025
Biomedical and Health Sciences
As global energy needs have skyrocketed in the past decade, energy byproduct has increased in tandem. Places like Mooresville, North Carolina; Pineville, Indiana; and southeastern Puerto Ric…
ISEF · 2025
Biomedical and Health Sciences
Parkinson’s disease (PD) is a common neurodegenerative disease (NDD) that is characterized by the gradual loss of dopaminergic neurons and progressive motor impairment. Recent studies sugges…
ISEF · 2025
Translational Medical Science
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor prognosis, signifying a pressing need for novel therapeutic strategies. This study investigated the effect of…
ISEF · 2025
Physics and Astronomy
This study’s goal was to determine which pump laser configuration would stimulate type-1 spontaneous parametric down-conversion (SPDC) in beta barium borate (BBO) crystals such that the numb…
ISEF · 2025
Physics and Astronomy
NASA's Kepler Mission has discovered over 5,800 exoplanets in our galaxy, revealing a puzzling phenomenon known as the "radius cliff." The "radius cliff" is a sharp decline in the number of…
ISEF · 2025
Biomedical and Health Sciences
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the progressive degeneration of motor neurons, leading to muscle weakness, paralysis, and ultimatel…
ISEF · 2025
Cellular and Molecular Biology
Toxoplasma gondii (T. gondii) is an obligate intracellular parasite that persistently infects the central nervous system (CNS) of up to a third of the world’s population. In the immune compe…
ISEF · 2025
Cellular and Molecular Biology
Research showed significant changes in the brain of Drosophila melanogaster such as fewer stem cells and smaller brains after knocking out nhes in the brain. Nhes also affect a decline in ag…
ISEF · 2025
Biochemistry
Pancreatic Ductal Adenocarcinoma (PDAC) remains one of the most lethal cancers with a significantly low 5-year survival rate. PDAC is typically diagnosed in individuals over 65, suggesting t…
ISEF · 2025
Biochemistry
Pesticides are used in agriculture to deter plant pests and pathogens, but are known to have a detrimental effect on the environment and ecosystem because of their ability and frequency to k…
ISEF · 2025
Animal Sciences
The project targeted two specific nutrients types, fiber and potassium and see if it has a correlation with methane productivity in cow manure. The goal was to increase the targeted nutrient…
ISEF · 2025
Cellular and Molecular Biology
The endothelium, a layer of cells lining the inner wall of coronary arteries, contributes to blood hemostasis and healthy function of the heart. In coronary artery disease (CAD), endothelial…
ISEF · 2025
Plant Sciences
Crop damage caused by environmental stress and diseases pose a significant challenge to global food security and agricultural sustainability. Conventional chemical treatments can have harmfu…
ISEF · 2025
Translational Medical Science
Lung cancer remains the as the leading cause of cancer-related deaths worldwide, with an estimated 124,730 deaths in the United States alone in 2025. The situation in Hawai?i is especially c…
ISEF · 2025
Cellular and Molecular Biology
Epidemiological studies performed in large cohorts among different populations indicate a negative correlation between developing melanoma skin cancer and drinking coffee. While coffee’s pop…
ISEF · 2025
Biomedical and Health Sciences
Diabetes is one of the most actual issues in today's world. 90% of 800 million diabetics have type 2 diabetes. In our experiment, we studied the Galega Officinnalis plant, which is used in t…
ISEF · 2025
Biomedical and Health Sciences
Early diagnosis of neurodevelopmental disorders (NDDs) such as Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) enables early intervention and is crucial fo…
ISEF · 2025
Translational Medical Science
The use of therapeutic siRNA to silence genes in a sequence-specific manner has been limited by its need for delivery to target cells. However, while antibody-mediated siRNA delivery shows p…
ISEF · 2025
Engineering Technology: Statics & Dynamics
The engineering goal of my project is to make and test the efficiency of an ion propulsion device. The trials will include multiple variables such as same terminal shape/spacing and the way…
ISEF · 2025
Embedded Systems
In 2023, U.S. fire departments responded to 1.39 million fires, resulting in 3,670 civilian deaths, 13,350 injuries, and $23 billion in damages (Hall, 2024). This investigation developed a g…
ISEF · 2025
Microbiology
Microplastic pollution presents a significant environmental challenge, particularly in soil ecosystems, where its effects on microbial communities remain poorly understood. This study aimed…
ISEF · 2025
Physics and Astronomy
Pill Millipedes play a vital role in humid forest ecosystems, functioning as decomposers and indicators of environmental health, thereby supporting biodiversity. One of their most interestin…
ISEF · 2025
Engineering Technology: Statics & Dynamics
Jetstream is the world’s fastest drone, flying at 40% of the speed of sound. Jetstream paves the way for future high-speed-drone design, enabling future drones to tackle a new realm of high-…
ISEF · 2025
Plant Sciences
In a global context, there are numerous communities with geographical and/or physical limitations that face poor quality of life. This research proposes a sustainable system for fertilizers…
ISEF · 2025
Computational Biology and Bioinformatics
Neurodegenerative disease therapeutic development faces hurdles from multi-omic complexity and the poor interpretability of standard ML models (e.g., MLPs), limiting target discovery. We dev…
ISEF · 2025
Biomedical and Health Sciences
Late-stage keratoconus is a progressive corneal disease causing severe visual loss. Conventional treatments, like corneal rings, often fail in advanced cases due to insufficient tensile stre…
ISEF · 2025
Translational Medical Science
95% of chronic kidney disease (CKD) patients miss early detection, mostly diagnosed at late stages, contributing to an annual mortality of 11 million globally. Current screening methods, suc…
ISEF · 2025
Mathematics
In traditional Sudoku, players are tasked with filling a 9x9 board with the numbers 1 through 9, with each number appearing once and not repeating in each column, row, and 3x3 subgrid. In Ki…