Browse real student projects, abstracts, and awards.
ISEF · 2025
Computational Biology and Bioinformatics
A solid tumor is an abnormal mass of uncontrolled cell growth, typically originating in the breast, lung, or prostate. Its physiological features make treatment by traditional methods diffic…
ISEF · 2025
Behavioral and Social Sciences
This research project aims to create an artificial intelligence tool to improve social communication for neurodivergent individuals, especially those with autism spectrum disorder. The test…
ISEF · 2025
Robotics and Intelligent Machines
The engineering design process uses repeated steps to produce the desired design. It starts by identifying a problem, researching it, brainstorming solutions, prototyping, testing, and itera…
ISEF · 2025
Systems Software
Approximately 10% of people in the world are legally blind & 2% of those are totally blind. This can lead to accidents happening in this population's everyday life. Current tools available t…
ISEF · 2025
Robotics and Intelligent Machines
Effective structural health monitoring (SHM) of carbon steel structures is critical, but is limited by traditional methods in efficiently identifying fine cracks. Thus, this project aims to…
ISEF · 2025
Computational Biology and Bioinformatics
Globally, health issues such as antibiotic-resistant infections and cancer become increasingly severe; however, the extensive time and cost required for drug development impose a significant…
ISEF · 2025
Computational Biology and Bioinformatics
Asthma and chronic obstructive pulmonary disease (COPD) are complex respiratory disorders with variable disease progression and heterogeneous treatment responses. While biologic therapies su…
ISEF · 2025
Biomedical Engineering
Heart failure (HF) is a leading cause of death globally, impacting 60 million people worldwide and leading to 17.9 million deaths. Traditional ventricular assist devices (VADs), a common sol…
ISEF · 2025
Microbiology
To use AI technology to evaluate the structural proteins of the ESX-1 secretion system of Mycobacterium tuberculosis and experimentally assess the potential of EccA1 as a preventive DNA vacc…
ISEF · 2025
Biomedical Engineering
The engineering goal is to see if by taking a picture of an Evolut R valve, and then placing that image into artificial intelligence, and creating a file, if we could then change the size of…
ISEF · 2025
Biomedical Engineering
With 70% of rural healthcare clinics lacking basic ophthalmic equipment, most parents only end up taking their children for professional eye exams when the problem has already escalated, but…
ISEF · 2025
Microbiology
Klebsiella pneumoniae (KP) has been raging around the world recently, posing a threat to public health and also becoming a significant burden on healthcare systems. Although antibiotics were…
ISEF · 2025
Technology Enhances the Arts
The purpose of this project is to find a mathematical process to enhance images of a subject, deriving results purely from data in the subject being observed rather than relying on AI assump…
ISEF · 2025
Chemistry
Carbon has several known allotropes, graphite, diamond, amorphous; there are also cylindrical nanotubes and spherical fullerenes. Scientists are trying to make another hypothetical allotrope…
ISEF · 2025
Plant Sciences
This project investigated how allelopathic compounds from the invasive Cynara cardunculus (artichoke thistle) affect native species in the endangered coastal sage scrub habitat (CSS) at Blac…
ISEF · 2025
Materials Science
With applications ranging from astronomy and environmental monitoring to night vision and medical diagnostics, infrared (IR) imaging technologies are more in demand than ever. Despite the fa…
ISEF · 2025
Computational Biology and Bioinformatics
This research expands existing Olfactory Receptor (OR) studies, exploring their potential in cancer drug therapy and establishing a novel pipeline applicable to similar G protein-coupled rec…
ISEF · 2025
Translational Medical Science
Coagulopathy defined as abnormal blood coagulation can cause thrombosis (hypercoagulation) or hemorrhage (hypocoagulation) leading to death. Current assays that provide a complete assessment…
ISEF · 2025
Computational Biology and Bioinformatics
Richter Syndrome (RS) is a sudden complication that can occur in 2-10% of Chronic Lymphocytic Leukemia (CLL) patients where a second, much more dangerous and aggressive lymphoma can spring u…
ISEF · 2025
Biomedical and Health Sciences
In 2023, the Brazilian Amazon had the worst drought in history. People from the rural and indigenous areas suffered from many problems, especially hunger. In search of a food alternative fro…
ISEF · 2025
Biomedical Engineering
Every day, thousands of individuals are diagnosed with cancer. Cancer is a common disease caused by uncontrolled multiplication of abnormal cells in the body. All different types of cells ar…
ISEF · 2025
Microbiology
Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains the deadliest infectious disease, responsible for approximately 1.25 million deaths and 10 million new cases in 2023. A major…
ISEF · 2025
Engineering Technology: Statics & Dynamics
This project aims to engineer the next-generation cooling device using ionic wind technology. This system consists of a high-voltage emitter and collector electrodes that generate and attrac…
ISEF · 2025
Animal Sciences
As interest in marine resource development and naval capability grows, the need for efficient and maneuverable marine exploration technologies has become urgent. Current large-scale explorat…
ISEF · 2025
Earth and Environmental Sciences
In 2024, climate change-induced wildfires burned over 8 million acres across the U.S. and my home state of Oregon faced its most destructive wildfire year on record, with 1.9 million acres s…
ISEF · 2025
Computational Biology and Bioinformatics
Autism Spectrum Disorder (ASD), a neurodevelopmental disorder marked by heterogeneity, necessitates innovative diagnostic approaches. This study pioneers a multimodal deep ensemble network,…
ISEF · 2025
Biomedical Engineering
Dysarthria is a motor-speech disorder that impairs the control of muscles required for clear speech, creating serious communication barriers that cannot be fully resolved by existing Augment…
ISEF · 2025
Systems Software
Gray Leaf Spot (GLS), caused by the fungal pathogens Cercospora zeae-maydis and Cercospora zeina, represents a significant challenge in corn production, resulting in annual economic losses a…
ISEF · 2025
Translational Medical Science
Artificial Intelligence (AI) models like Convolutional Neural Networks (CNNs) are becoming powerful tools in medical imaging, but their “black box” nature limits clinical use. Doctors need t…
ISEF · 2025
Embedded Systems
The most significant weakness and vulnerability in the wildfire response chain lies in the early detection/reaction phase. The physics of wildfire growth are exponential. Any reduction in re…