Browse real student projects, abstracts, and awards.
ISEF · 2026
Computational Biology and Bioinformatics
Fluoroquinolones (FQs) are widely prescribed antibiotics with many beneficial pharmacological effects however; they carry FDA black box warnings for neurological side effects. This disconnec…
ISEF · 2026
Environmental Engineering
Lithium is essential for rechargeable batteries, and demand is rising rapidly due to E-mobility and clean energy growth. About 66% of the world's lithium is produced through brine pond evapo…
ISEF · 2026
Technology Enhances the Arts
Glass waste in coastal environments poses long-term ecological risks due to its non-biodegradable nature. Sea Gems aimed to transform sea glass into sustainable jewellery while educating con…
ISEF · 2026
Plant Sciences
Soil Salinization accelerated by sea-level rise and salt-water intrusion poses a critical threat to global food security, significantly impacting staple crops like rice (Genua-Olmedo et al.,…
ISEF · 2026
Behavioral and Social Sciences
The assessment of Post-Traumatic Stress Disorder (PTSD) currently relies on interviews and self-reported questionnaires, which limit both objective assessment and early clinical diagnosis. T…
ISEF · 2026
Biomedical Engineering
Pathological hand tremors affect 5% of the world population, yet diagnosis remains a subjective 0-4 visual score, and treatments are dangerous (Beta-Blockers), ineffective (orthotics), or ex…
ISEF · 2026
Cellular and Molecular Biology
Glioblastoma is a highly aggressive and treatment-resistant brain tumor with a five-year survival rate of 6.9%, necessitating exploration of novel therapeutic strategies. Transient receptor…
ISEF · 2026
Translational Medical Science
Atypical Chemokine Receptor 1 (ACKR1/DARC) is a non-signaling chemokine receptor expressed on erythrocytes and endothelial cells. In tumors, ACKR1 modulates inflammation, chemokine gradients…
ISEF · 2026
Materials Science
Hydrophobic (or water-repellent) coatings are of particular interest because of their broad relevance to surface protection, self-cleaning, and environmental durability. Here, we focus on tr…
ISEF · 2026
Biomedical Engineering
The purpose of this project is to develop a low-cost electrochemical sensor capable of detecting concentrations of an analog similar to kynurenic acid (L-tryptophan). This was accomplished b…
ISEF · 2026
Biomedical Engineering
Imagine your immune system is an army of tiny soldiers called T cells, and their job is to hunt down and destroy cancer. This is called T cell therapy, and it is a very hopeful way to treat…
ISEF · 2026
Software Design
Thermal anomaly detection from unmanned aerial vehicles (UAVs) is increasingly used for applications such as early wildfire discovery, post-disaster monitoring, and infrastructure inspection…
ISEF · 2026
Translational Medical Science
Retinal degenerative diseases (RDDs) affect 300 million patients worldwide. Current imaging techniques detect RDDs in late stages after significant vision loss. Approximately 40% of Retinal…
ISEF · 2026
Behavioral and Social Sciences
Feminicide remains one of the most severe expressions of gender-based violence worldwide, reflecting structural inequalities of race, territory, age, and social context. In Brazil, underrepo…
ISEF · 2026
Cellular and Molecular Biology
Cardiovascular disease remains the leading global cause of mortality, with myocardial infarction resulting in permanent myocardial loss due to the limited regenerative capacity of adult card…
ISEF · 2026
Behavioral and Social Sciences
Growing up, I often compared myself to others, which led me to wonder whether it was possible to quantify self-esteem and how academic performance can influence it. Because the pressures fol…
ISEF · 2026
Computational Biology and Bioinformatics
Alphafold, a protein-folding prediction tool created by Google DeepMind, has shown unprecedented ability to accurately simulate the 3D structure of proteins given an amino acid sequence. Bas…
ISEF · 2026
Translational Medical Science
Melanoma is the most fatal type of skin cancer, taking over 50,000 lives annually. While advances in checkpoint immunotherapy have decreased mortality rates, it is difficult to determine whi…
ISEF · 2026
Embedded Systems
Each year, over 350,000 people in the United States experience out-of-hospital cardiac arrest, and nearly 90% do not survive. Early cardiopulmonary resuscitation (CPR) can triple survival ra…
ISEF · 2026
Mathematics
Cryptographic systems securing global communications depend on computationally hard mathematical problems. Yet, the divisibility structure of combinatorial objects like Pascal’s Triangle rem…
ISEF · 2026
Chemistry
Silicon (Si) anodes could revolutionize lithium-ion batteries by expanding capacity eleven-fold. However, Si expansion during charging compromises battery integrity, preventing practical app…
ISEF · 2026
Materials Science
Shear-thickening fluid (STF) impregnation into aramid-fiber materials is a new concept with most of its advancements happening within the past ten years. This project tested two samples, a 1…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Middle-aged and elderly people are prone to frozen shoulder, which causes shoulder pain and restricted arm movement, significantly affecting their daily lives. Doctors usually recommend reha…
ISEF · 2026
Robotics and Intelligent Machines
This study aims to build an on-device edge computing system that leverages Vision-Language Models (VLMs) in place of the conventionally used Convolutional Neural Networks (CNNs) for real-tim…
ISEF · 2026
Biomedical Engineering
This engineering project develops a low-cost, portable device to quantify back pain risk in youth, aiming to reduce progression of chronic spinal conditions. Back pain affects 39% of adults…
ISEF · 2026
Cellular and Molecular Biology
MicroRNAs (miRNAs), small noncoding RNA genes, play crucial roles in regulating gene expression in human development and cancer. The let-7 miRNA is involved in various cellular processes, in…
ISEF · 2026
Robotics and Intelligent Machines
As computer vision systems become increasingly integrated into everyday life, it is imperative to consider the deficiencies and biases present in our computer algorithms. One such bias is sp…
ISEF · 2026
Mathematics
Airlines have increasingly adopted flexible refund policies that allow passengers to cancel tickets in exchange for time-limited travel credits. While these policies reduce customer risk, th…
ISEF · 2026
Plant Sciences
The Normalized Difference Vegetation Index (NDVI) measures the health of plants. This project used two cameras, one measuring red light and the other near infrared light, to calculate the ND…
ISEF · 2026
Environmental Engineering
The material use of shade balls has become an area of concern in recent years. The water used in the production of shade balls and other water covers often offsets the water that is retained…