ISEF · 2025
Stellar Tracer
Physics and Astronomy
Tidal tails form in open clusters due to two-body relaxation and gas expulsion (Kroupa et al., ApJ, 2024). Mapping tidal tail star trajectories provides key insights into understanding open…
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ISEF · 2025
Sticky States and the Adhesion Effect: A Novel Model of Directional Evolution Without Darwinian Selection
Computational Biology and Bioinformatics
Traditional Darwinian models of evolution treat adaptive selection as the primary evolutionary factor for most traits. Although this approach is predictive in many cases, it struggles to exp…
ISEF · 2025
STRiDE: A Real-Time Gait Tracking System for Early Parkinson's Disease Assessment Using Spatiotemporal Analysis of Ground Reaction Forces
Behavioral and Social Sciences
Parkinson's disease (PD) is a chronic neurodegenerative disorder affecting over 10 million people worldwide. Gait impairments are a key indicator of brain-body dysfunction in PD. However, ea…
ISEF · 2025
Structure-Guided Engineering of Ancestrally Derived AAV Capsids: Enhancing Precision Gene Therapy Through the Rational De-Targeting of Hepatic Tropism
Cellular and Molecular Biology
Approximately 5.9% of the global population—over 300 million people—suffer from rare genetic disorders, many of which require AAV-based gene therapy. AAV-B3, an ancestrally derived serotype…
ISEF · 2025
Study of Irreversible Electroporation of Potato Tissue by EIS Spectroscopic Analysis With the Aim of Optimizing Pulse Protocol Testing Methods for Cancer Treatment
Biomedical Engineering
Irreversible electroporation (IRE) is an innovative technique that disrupts cellular homeostasis, functioning similarly to non-thermal apoptosis. This method enables the selective ablation o…
ISEF · 2025
Study on the Efficacy of Mikania micrantha Extracts Incorporated With Nano Clay as a Pest Controlling Method Against Aphids
Plant Sciences
This study explores the pesticidal efficacy of Mikania micrantha (bitter vine, wathupalu) leaf extracts to be used as a freely available and low cost botanical pesticide against Myzus persic…
ISEF · 2025
StutterZero: End-to-End Speech Conversion to Transcribe and Correct Stutters
Computational Biology and Bioinformatics
Over 70 million in the world suffer from stuttering, a speech impairment characterized by involuntary disruptions during normal speech. This can create communication barriers and limiting ac…
ISEF · 2025
SubArc: An Inexpensive, High Resolution, Open Source, Absolute Magnetic Rotary Encoder
Embedded Systems
High resolution absolute rotary encoders are essential to precision applications like tracking telescopes, semiconductor manufacturing, low-tolerance machining, and robotic mechanisms. Howev…
ISEF · 2025
Sundancer: Solar Powered Autonomous UAV for Natural Disaster Relief
Engineering Technology: Statics & Dynamics
In natural disaster affected areas, communications infrastructure is often disabled. Without communication systems, search and rescue teams are less able to locate victims and coordinate wit…
ISEF · 2025
Sustainable Biofuel Production Through Multimode Biocatalysis Using Enzymes Extracted and Concentrated From Household Waste
Biochemistry
Biofuels are vital in combating climate change by offering a low-carbon alternative to fossil fuels, thus reducing greenhouse gas emissions. Efficiently converting waste materials into fuel…
ISEF · 2025
Sustainable Energy Conversion: A Solar Cell Chip With Built-In DC to AC Transformation
Energy: Sustainable Materials and Design
This study presents an innovative solar cell chip that integrates micro-capacitors and micro-converters directly into the cell architecture to streamline DC-to-AC energy conversion. Traditio…
ISEF · 2025
Sustainable Recycling of End-of-Life Solar Panels: Utilizing Recovered Glass in Concrete for Sand Reduction and Waste Minimization
Environmental Engineering
The alarming rise in solar photovoltaic (PV) waste, particularly non-biodegradable glass, poses a growing environmental concern, with global waste projected to reach 78 million metric tons b…
ISEF · 2025
Sustainable Self-Charging Aqueous Zinc-lon Battery Using CaVO Nanostructures Prepared From Recycled Mortar
Energy: Sustainable Materials and Design
The escalating global energy demand necessitates innovative and efficient storage solutions. However, conventional energy storage devices often require external charging, which can be proble…
ISEF · 2025
Sustainable Technologies for Reducing Phosphorus Leaching Using Plant Growth Promoting Rhizobacteria
Plant Sciences
Fertilizers applied to soilless growing substrates in controlled environment agriculture (CEA) often leach nutrients like phosphorus (P), and this leads to environmental pollution. The objec…
ISEF · 2025
Sustainable UV-Curable Monomers Derived From Glycerol for 3D Printing Applications
Materials Science
The surplus of glycerol waste produced during the process of biodiesel production in the United States has posed a new challenge to the sustainability of the biofuel industry. Crude glycerol…
ISEF · 2025
SUSTAINWARE: A Sustainable Alternative for Stoneware Production
Materials Science
This study proposes the development of eco-friendly stoneware using waste glass and rice husk ash (RHA). The global recycling rate for glass is low, at approximately 20%, while RHA is a sign…
ISEF · 2025
Symmetry-Preserving Variational Autoencoder and Latent Space Rectified Flow Diffusion for Accelerated Materials Discovery With Geometric Graph Neural Networks and Integrated Property Network Multi-Layer Perceptron
Robotics and Intelligent Machines
Advancements in materials science have driven technological progress, yet discovering new materials remains challenging due to resource-intensive laboratory experiments, costly characterizat…
ISEF · 2025
SynaptiQ: Detection and Prevention of Hospital Induced Delirium
Embedded Systems
Hospital-induced Delirium (HID) affects 30% of patients causing fluctuating cognitive disturbances, tripling mortality risk and costing North American healthcare systems $164 billion annuall…
ISEF · 2025
Synergistic Effects of D-Amino Acids and Ciprofloxacin on Staphylococcus epidermidis Biofilms and Viability
Biochemistry
Staphylococcus epidermidis biofilms resist antibiotics like ciprofloxacin. This project evaluates D-amino acids as adjuvants to increase ciprofloxacin efficacy. Combining ciprofloxacin with…
ISEF · 2025
Synergistic HI and Ag Doping Strategies for Efficient Lead-Free Perovskites in Indoor Photovoltaics
Energy: Sustainable Materials and Design
With the advancement of Internet of Things (IoT) technology, businesses are seeking to substitute rapidly deteriorating batteries with more efficient, wireless, and environmentally sustainab…
ISEF · 2025
Synthesis and Biological Evaluation of Benzoylferrocene as an Anti-Cancer and Antioxidant Agent
Biochemistry
This research involved the synthesis of Benzoylferrocene and evaluation of Benzoylferrocene’s potential anti-breast cancer and antioxidant activity. No investigation has been done surroundin…
ISEF · 2025
Synthesis and Characterization of Cellulose Acetate Polymer From Pinus spp. Pine Cones
Materials Science
Due to the growing demand for sustainable materials and the need to reduce the environmental impact of conventional polymers, this study aims to the use of Pinus spp. pine cones, an underuti…
ISEF · 2025
Synthesis and Characterization of Silver Nanoparticles for the Detection of Heavy Metals
Materials Science
Traditional detection methods for heavy metals in groundwater often lack the sensitivity and efficiency needed for real-time monitoring, making the development of portable and sensitive dete…
ISEF · 2025
Synthesis of Borophene and Determination of Its Hydrogen Storage Capacity Using QCM for Potential Applications in the Automotive Industry
Energy: Sustainable Materials and Design
Borophene is a newly synthesized material that is considered superior in various properties. Due to the challenges of hydrogen storage and transportation, hydrogen energy has not fully devel…
ISEF · 2025
Synthesis of Molecular Sensor Based on the Curcumin Dye Extracted From Curcuma longa L. To Detect Long Chain Aldehydes as the Lung Cancer Biomarker
Chemistry
This project synthesis and design of a molecular encapsulating particle EC@ccdz, as a novel approach for screening diagnosis of lung cancer to reduce mortality rates and the complexity of ad…
ISEF · 2025
Synthesis of New HIPK Inhibitors Based on furo[3,2-b]pyridine Motif
Chemistry
Signaling pathways of specific protein kinases are one of the main forms of intercellular communication. The information transfer is based on the chain of activation responses, often initiat…
ISEF · 2025
Tackling Forever Chemicals PFAS for Environmental Stewardship
Environmental Engineering
Per- and polyfluoroalkyl substances (PFAS) have been widely used in various products such as non-stick cookware and fire-fighting form. Due to their non-degradable properties ascribed to the…
ISEF · 2025
Tactile Vision: A Low-Cost Haptic Interface for Image Perception in Visually Impaired Users
Technology Enhances the Arts
Haptic feedback technology offers innovative ways for visually impaired individuals to interact with their surroundings. Current solutions, however, are often prohibitively expensive and lac…
ISEF · 2025
Tailsense: Classifying Dogs' Emotions Using Barks and Images Based on Breed
Animal Sciences
Purpose Dog barks and visual cues are main channels through which dogs communicate their emotional states, such as anger, sadness, and excitement. However, accurately interpreting these is a…
ISEF · 2025
TAK1 Signaling Regulates the Secretory Capacity of Skeletal Muscle Fibroblasts in Response to Inflammatory Cytokines
Cellular and Molecular Biology
Skeletal muscle cells regulate and provide many bodily functions. Skeletal muscle cells support movement, posture, and temperature regulation. In addition, skeletal muscle triggers an immune…