Browse real student projects, abstracts, and awards.
ISEF · 2025
Biomedical and Health Sciences
COVID-19, caused by SARS-CoV-2, has been associated with a range of cardiovascular complications, including arrhythmias and cardiomyopathy. This study investigates how the SARS-CoV-2 spike p…
ISEF · 2025
Translational Medical Science
Polycystic Ovarian Syndrome (PCOS) is an endocrine disorder affecting millions of women worldwide. It is characterized by irregular periods, alopecia, hyperandrogenism, infertility, hirsutis…
ISEF · 2025
Behavioral and Social Sciences
Olfaction or the sense of smell plays a fundamental role in the animal kingdom's survival and may serve a marker for human disease, including mental disorders. This study’s objectives are: 1…
ISEF · 2025
Environmental Engineering
Science of Autonomy: Optimal path planning optimizes maritime navigation by analyzing environmental factors such as ocean currents to determine time-optimal routes in the ocean. I hypothesiz…
ISEF · 2025
Microbiology
Antimicrobial resistance (AMR), often referred to as a “silent pandemic” in scientific discussions, has become one of the most pressing threats to global health. AMR plays a key role in micr…
ISEF · 2025
Environmental Engineering
The high volumetric capacity (53 g H2/L), low toxicity, and ambient stability of formic acid (FA) make it a promising hydrogen carrier, yet efficiently extracting hydrogen in a clean and sca…
ISEF · 2025
Environmental Engineering
The NOAA defines microplastics as "plastic pieces less than five millimeters long." Microplastics have been found from the Mariana Trench to Mount Everest, and from the human brain to the pl…
ISEF · 2025
Systems Software
In the recent decade, autonomous systems like self-driving cars, drones, and robots have become widely used. They rely heavily on 3D perception of the surrounding environment and mapping tec…
ISEF · 2025
Systems Software
As cyber-attacks become increasingly common (72% increase from 2021), and as losses from cybercrime grow each year ($10.5 trillion by 2025), it is more important than ever for organizations…
ISEF · 2025
Physics and Astronomy
This study proposes a methodology to characterize asteroid 1777 Gehrels through its light curve and to derive an exploration orbit using reinforcement learning. A total of 120 images were co…
ISEF · 2025
Engineering Technology: Statics & Dynamics
The Rio Grande Gorge bridge has an average of six suicides/year, as compared to 13.6 suicides/year (Atkins-Witmer, Woods, 2013) for the Golden Gate bridge. Per capita, this is a comparable s…
ISEF · 2025
Engineering Technology: Statics & Dynamics
Each time a rocket is launched into the Earth's atmosphere it uses several thousands of gallons of chemical fuel per second. These chemical fuels, when being used in such large quantities, c…
ISEF · 2025
Materials Science
With more than 360 million tons of plastic produced each year, plastic pollution has become a critical issue as plastics accumulate in our environment and inside us; microplastics are even k…
ISEF · 2025
Microbiology
Quorum Sensing (QS) is a bacterial communication pathway that mediates population-based activity activities such as virulence, motility, conjugation, and biofilm formation. Specifically, QS-…
ISEF · 2025
Materials Science
This study aimed to develop a scalable, cost-effective method for producing high-quality silver nanoparticle (AgNP)-containing hydrogels. AgNPs (1–100 nm) are promising in biomedical applica…
ISEF · 2025
Chemistry
More than half the world's population, around 4.4 billion people, lack access to clean and safe drinking water. This is partially due to the contamination of synthetic organic dyes, which ar…
ISEF · 2025
Cellular and Molecular Biology
The purpose of this experiment was to design a cell model using a rat pheochromocytoma (PC12) cell to simulate Diabetic Peripheral Neuropathy (DPN). It was proposed that the higher the level…
ISEF · 2025
Materials Science
Micrometer size carbon separation plays a critical role in chemical and biological applications for instance, drug delivery (Yao et al., 2024) . For example, size uniformity is crucial for o…
ISEF · 2025
Chemistry
Our world has experienced major disasters over the past 50 years. Global warming and water pollution are the main causes. Birds and other creatures cannot be rescued and lose their lives on…
ISEF · 2025
Biomedical and Health Sciences
Triple-negative breast cancer (TNBC) is a subtype of breast cancer which has none of the known unique biomarkers of the other subtypes. There is no established targeted treatment for TNBC an…
ISEF · 2025
Biomedical Engineering
CRISPR-Cas9 has emerged as a catalyst in treating genetic diseases such as sickle cell disease and transfusion-dependent beta thalassemia. Multiplex CRISPR-Cas9 is a subsystem of CRISPR edit…
ISEF · 2025
Systems Software
This research investigates, from a mathematical and computational perspective, the process of image formation and reconstruction through Computed Tomography (CT), using algorithms implemente…
ISEF · 2025
Engineering Technology: Statics & Dynamics
Learning to skateboard is challenging and often leads to injury. Unlike bikes, skateboards do not have a universal training aid for beginners. This project aimed to create a device similar t…
ISEF · 2025
Biomedical Engineering
Skin cancer is a common yet curable disease if diagnosed early. This study developed SKIMP, a portable artificial intelligence-based diagnostic device, to facilitate early detection of skin…
ISEF · 2025
Engineering Technology: Statics & Dynamics
This project presents an innovative Thrust-Vectoring Unmanned Aerial Vehicle (UAV) specifically designed to perform contact-based inspections(ultrasonic crack detection, wave check, and adhe…
ISEF · 2025
Biomedical and Health Sciences
Individuals with conditions like "lazy eye," amblyopia, and strabismus have been experiencing issues with peripheral vision. This study aims to test if VR use in gaming can improve periphera…
ISEF · 2025
Mathematics
The smooth sliceness of a knot is an important property with connections to longstanding problems in topology such as the smooth four-dimensional Poincare Conjecture (4SPC) and the Slice-Rib…
ISEF · 2025
Chemistry
United Nations Sustainable Development Goals provide a shared blueprint for peace and prosperity for people and the planet. Goal 12: Responsible Consumption and Production is closely aligned…
ISEF · 2025
Computational Biology and Bioinformatics
MicroRNAs (miRNAs) with highly dysregulated expression levels, have so far constituted the focus of disease-specific biomarkers research. However, the complex regulating mechanisms between m…
ISEF · 2025
Environmental Engineering
Direct Air CO2 Capture (DAC) is a critical technology for generating negative emissions to reduce atmospheric CO2 concentrations to preindustrial levels by 2050. One of DAC's most significan…