Browse real student projects, abstracts, and awards.
ISEF · 2026
Biomedical and Health Sciences
Hepatitis B virus (HBV) infects 300 million people worldwide, causing 1.3 million annual deaths. Current treatments can suppress viral replication but fail to eliminate covalently closed cir…
ISEF · 2026
Biomedical Engineering
Modern High-Throughput Screening (HTS) is a system used in drug discovery labs that can rapidly test hundreds of thousands of chemicals against a target in a disease with the aim of developi…
ISEF · 2026
Biomedical Engineering
Partial-thickness burns make up 85.4% of all clinical cases (Ji et al., 2024). At the same time, those in underrepresented areas display higher burn incidences and are less likely to adminis…
ISEF · 2026
Animal Sciences
Raw fish (sashimi) consumption is common in Japan, and angle-dependent coloration is regularly observed during meals. Although similar coloration has been reported in meat, few studies have…
ISEF · 2026
Animal Sciences
Honeybees exhibit trophallaxis, a behavior in which a recipient extends their proboscis to drink a nectar droplet held by the donor's mouthparts. During this process, the recipient's antenna…
ISEF · 2026
Embedded Systems
Wilderness search-and-rescue (SAR) operations across U.S. national parks exceed 4,000 to 4,500 incidents annually, with over 40,000 missions between 2015 and 2025. In August 2024, a multi-da…
ISEF · 2026
Computational Biology and Bioinformatics
Drug-resistant epilepsy affects nearly one-third of patients and often requires surgical intervention; however, success depends on accurate localization of the seizure onset zone (SOZ), curr…
ISEF · 2026
Physics and Astronomy
This project explored whether quantum batteries, which utilize the quantum mechanical principles of superposition and entanglement, have the potential to serve as an important energy storage…
ISEF · 2026
Physics and Astronomy
Quantum computers use the principles of quantum mechanics — superposition, entanglement, and coherence — to solve problems that classical computers simply cannot. In the current era of Noisy…
ISEF · 2026
Microbiology
Phytochemicals are naturally occurring compounds in plants, relatively understudied for their ability to interfere with bacterial communication mechanisms, and the underlying modes of action…
ISEF · 2026
Biomedical and Health Sciences
This project aims to explore the mechanisms the rabies virus uses to evade the immune system while traveling through the nervous system. We are motivated by the challenge of comprehending ho…
ISEF · 2026
Biomedical Engineering
Obstructive and restrictive respiratory diseases are major global health challenges and are associated with prolonged exposure to smoke and air pollution. Among these conditions, Chronic Obs…
ISEF · 2026
Environmental Engineering
Continuous water quality monitoring is critical for safeguarding aquatic ecosystems, informing environmental management decisions, and supporting public health. However, conventional systems…
ISEF · 2026
Translational Medical Science
Norovirus is the leading cause of gastroenteritis worldwide, causing over 685 million cases each year globally, yet rapid and sensitive detection tools remain limited. All diagnostic technol…
ISEF · 2026
Physics and Astronomy
Coronal magnetic fields are a driving force behind the formation and evolution of solar energetic particle events, which are known to disrupt critical ground and space infrastructure, causin…
ISEF · 2026
Translational Medical Science
Peritoneal dialysis, one type of dialysis for patients with end-stage renal disease, can be complicated by peritonitis, a life-threatening inflammation of the peritoneum typically caused by…
ISEF · 2026
Biomedical Engineering
symptoms of childhood Attention-Deficit/Hyperactivity Disorder (ADHD) may lead to socioeconomic consequences in adulthood, including long-term unemployment. Access to traditional clinical ca…
ISEF · 2026
Plant Sciences
Paclitaxel, a critical plant-derived chemical harvested from yew trees, is implemented in numerous applications including various chemotherapy treatments. The conventional method of paclitax…
ISEF · 2026
Materials Science
This study evaluates the reuse of polyethylene terephthalate (PET) from plastic bottles for filament production in 3D printing via thermoplastic pultrusion, using a PET Machine based on the…
ISEF · 2026
Software Design
This research shows LLM-generated design can be customized by Deep Learning’s Reinforcement learning with non-verbal(personal preference) human feedback. In space design, most of its applica…
ISEF · 2026
Energy: Sustainable Materials and Design
American Samoa’s reliance on imported fossil fuels increases vulnerability to price volatility and supply disruptions, highlighting the need for locally sourced renewable energy. This study…
ISEF · 2026
Environmental Engineering
Single-use paper items used in food packaging like straws and food wrappers are often coated with plastic or polyfluoroalkyl substances (PFAS, also known as "forever chemicals") to make them…
ISEF · 2026
Materials Science
This study presented RegoCrete-BGX, a fiber reinforced, multi-aggregate concrete developed using lunar regolith, basaltic rock, and waste glass designed for future space applications. The co…
ISEF · 2026
Biomedical and Health Sciences
Lung cancer is the leading cause of cancer-related deaths and is known to effectively colonize other parts of the body, often evading the immune system as it metastasizes or spreads. Pre-lim…
ISEF · 2026
Computational Biology and Bioinformatics
Chimeric Antigen Receptor T-cell (CAR-T) therapy is a breakthrough cancer treatment that genetically engineers patients' immune cells to target and destroy malignancies. While highly success…
ISEF · 2026
Robotics and Intelligent Machines
Autonomous drone research has become increasingly important, yet there are many burdens which make its access limited. Especially for autonomous drone racing, high-end motion-capture systems…
ISEF · 2026
Behavioral and Social Sciences
Navigation inflexibility is a symptom observed in approximately 50% of early Alzheimer's disease (AD). However, why and how this disorder occurs has remained unclear. Computational modeling…
ISEF · 2026
Biomedical and Health Sciences
Dysregulated astrocytic Ca2+ signaling is a key driver of high-burden CNS disorders, including Alzheimer’s and stroke, yet existing neuromodulation strategies remain invasive and neuron-cent…
ISEF · 2026
Chemistry
This study was performed to investigate the efficiency of different methods to extract lignin, which is used for many different purposes in industry. Six types of wood were used. All types o…
ISEF · 2026
Chemistry
Ammonia fertilizers feed over half of the global population. However, its synthesis through the Haber-Bosch process is extremely unsustainable, leading to over 20% of global chemical CO2 emi…