Browse real student projects, abstracts, and awards.
ISEF · 2026
Biochemistry
The main goal of the project is to develop a functional, inexpensive and easily reproducible method for testing the interactions of gastrointestinal glycoproteins, mucins, with a wide range…
ISEF · 2026
Earth and Environmental Sciences
Urban growth and the associated loss of vegetation and green spaces in Gauteng Province, South Africa, were analysed for the period 2016-2040. The study examined land cover change, particula…
ISEF · 2026
Computational Biology and Bioinformatics
The global shortage of donor organs has renewed interest in xenotransplantation, with genetically modified pigs (Sus scrofa domesticus) emerging as potential donors for human liver transplan…
ISEF · 2026
Plant Sciences
Powdery mildew is one of the most widespread and damaging agricultural diseases in the world. As the nation's leading agricultural region, Fresno, California’s 9 billion annual crop revenue…
ISEF · 2026
Physics and Astronomy
Phase-change materials (PCMs) offer a viable alternative for thermal management and thermal energy storage due to their capacity to store substantial latent heat. This study investigates pre…
ISEF · 2026
Materials Science
Diethylene glycol DEG contamination in medicinal syrups represents a persistent global health crisis, having caused over 300 child fatalities since 2022 alone, and occurring recently as of O…
ISEF · 2026
Plant Sciences
Salinity in soil is one of the greatest environmental stressors for plants. It has been estimated that worldwide 20% of total cultivated and 30% of irrigated agricultural lands are afflicted…
ISEF · 2026
Materials Science
More than 50 million tons of electronic equipment waste is generated per year, creating a strong demand for sustainable conductive materials. Yet, biodegradable conductive materials face a c…
ISEF · 2026
Materials Science
Plastic recycling is limited by mis-sorting across polymer families and additives. Current identification methods, such as SPI resin codes, labels, and visible/near-infrared/Fourier Transfor…
ISEF · 2026
Materials Science
Reducing carbon emissions in modern engineering has a critical tradeoff: materials must be lightweight to improve energy efficiency, yet strong enough to maintain structural integrity. Polye…
ISEF · 2026
Computational Biology and Bioinformatics
Purpose: Antimicrobial resistance causes 1.27 million deaths annually, yet 20–30% of proteins in pathogens remain uncharacterized. In Acinetobacter baumannii, the WHO's #1 priority pathogen,…
ISEF · 2026
Cellular and Molecular Biology
Multiple myeloma (MM) is a hematologic malignancy characterized by the uncontrolled proliferation of malignant plasma cells in the bone marrow. This study explored the potential of Pristimer…
ISEF · 2026
Animal Sciences
Microplastics are emerging environmental contaminants that have been detected in diverse ecosystems and biological systems. Increasing evidence suggests that these particles can induce oxida…
ISEF · 2026
Environmental Engineering
An estimated 92 million tons of textiles are discarded annually, yet fabric-to-fabric recycling accounts for less than 1% of production due to quality degradation and financial barriers. Thi…
ISEF · 2026
Materials Science
Many of the women and young girls in the low-income communities of Nigeria and sub-Saharan Africa can not afford conventional sanitary pads during their monthly menstrual cycle. This study i…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Suborbital research access costs $30k-$90k per mission, pricing out universities and independent researchers. Current reusable rockets depend on throttleable liquid engines for landing, whic…
ISEF · 2026
Mathematics
The theory of isogonal cubics is a powerful tool in proving the relations of angles. A part of the theory is deduced from Newton's theorems on conics. It is known that Newton's theorems can…
ISEF · 2026
Earth and Environmental Sciences
Microplastic (MP) contamination is a persistent environmental and public health threat, with polyethylene terephthalate (PET) MPs detected in drinking water, human blood, and placental tissu…
ISEF · 2026
Translational Medical Science
The healing process for severe thermal skin burns is often impeded by inflammation in the wound site and apoptosis, or programmed cell death. Typical treatment for burn wounds revolves aroun…
ISEF · 2026
Behavioral and Social Sciences
This project investigated which type of prompt would generate the most educationally effective response from Gemini as perceived by ninth grade students. Three ninth grade classes completed…
ISEF · 2026
Biomedical and Health Sciences
Glioblastoma (GBM) is the most common malignant brain cancer in adults, and patient survival still remains low. However, 83% of GBM cases have Telomerase Reverse Transcriptase promoter (TERT…
ISEF · 2026
Biomedical Engineering
Observing the mobility difficulties faced by wheelchair users, it becomes evident that the wheelchair model is often inadequate in relation to the daily environment and the accessibility nee…
ISEF · 2026
Biochemistry
Glioblastoma (GBM) is the most aggressive primary brain tumor. It is associated with poor survival and frequent development of resistance to the first-line chemotherapeutic agent temozolomid…
ISEF · 2026
Biochemistry
Acid-sensing ion channels (ASICs) are proton-gated, voltage-insensitive transmembrane proteins activated in acidic conditions, playing crucial roles in neuronal signaling. ASIC subunit 1a is…
ISEF · 2026
Biomedical Engineering
Hemorrhagic stroke occurs when a cerebral blood vessel ruptures, creating an urgent need for intervention to prevent fatality. Developing a neuroprotectant designed to form a synthetic barri…
ISEF · 2026
Embedded Systems
Air pollution causes over 7.9 million deaths each year and significantly contributes to non communicable diseases worldwide. Despite its serious health effects, many people are unaware of th…
ISEF · 2026
Engineering Technology: Statics & Dynamics
This project investigates the design and analysis of a rotary vane combustion engine (RVE) for portable generators to reduce engine imbalances, design complexity and increase torque producti…
ISEF · 2026
Materials Science
Following the infamous January 2025 Palisades Wildfire that devastated our Southern California community, an urgent need was identified for a lightweight respirator capable of protecting fir…
ISEF · 2026
Environmental Engineering
Minnesota’s 4 million drivers release heavy metals into the environment through their vehicles’ emissions. Copper, Lead, and Zinc account for 90% of vehicle-derived heavy metal pollution, wh…
ISEF · 2026
Cellular and Molecular Biology
Azole antifungals have served as frontline therapies for Candida infections. However, increasing azole-resistant Candida species presents a real clinical challenge requiring alternative anti…