Browse real student projects, abstracts, and awards.
ISEF · 2026
Physics and Astronomy
This project develops a first principles framework linking molecular-scale randomness to macroscopic fluid behavior through coarse-grained velocity fields. Modeling molecular collisions as a…
ISEF · 2026
Chemistry
Antimicrobial peptides (AMPs) are promising alternatives to conventional antibiotics due to their membrane-disruptive activity, but clinical translation is hindered by host cytotoxicity, poo…
ISEF · 2026
Materials Science
This study represents the synthesis and optimization of drug-loaded PLGA nanoparticles, and analysis of the structure, release, and in vitro kinetic studies. To enhance the bioavailability a…
ISEF · 2026
Energy: Sustainable Materials and Design
The increasing need for clean energy sources makes wind energy a major focus in this regard; however, currently, most wind turbines are installed in high-wind-speed locations, which are not…
ISEF · 2026
Energy: Sustainable Materials and Design
Installed wind power capacity has tripled in the last decade, motivating significant research in wind turbine performance optimization. Traditional optimization methods often evaluate blades…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Improving structural efficiency in aircraft wings is a critical objective in aerospace engineering, particularly as the industry moves toward more sustainable and lightweight designs. Wing r…
ISEF · 2026
Software Design
Electromyographic (EMG) signals carry neural control information and are widely utilized in neural-machine interfaces (NMIs) for applications such as prosthetic control and virtual reality.…
ISEF · 2026
Translational Medical Science
Alzheimer's is a neurodegenerative disease characterized by causes such as amyloid plaque accumulation, microglial dysfunction, and chronic neuroinflammation. Current treatments target the e…
ISEF · 2026
Biomedical and Health Sciences
Atherosclerosis is a condition characterized by a buildup of plaque in the arteries. Changes in blood flow cause endothelial cells to become atheroprone (susceptible to atherosclerosis patho…
ISEF · 2026
Materials Science
Despite decades of medical advancement, cancer continues to claim about 10 million lives annually. mRNA therapeutics represent a promising approach for cancer immunotherapy, particularly bec…
ISEF · 2026
Biomedical Engineering
The growing prevalence of antibiotic-resistant bacterial infections has impacted tens of millions of lives by reducing antibiotic effectiveness and worsening infections, which increases heal…
ISEF · 2026
Energy: Sustainable Materials and Design
Distributed sensors and low power-systems need sustainable power sources at micro-scale. Still bio-electrochemical systems are limited by low power density and unstable output of electricity…
ISEF · 2026
Environmental Engineering
Water pollution remains a significant issue for aquatic ecosystems, as most available absorbents for remediation are either non-biodegradable or toxic to aquatic life. The main goal of this…
ISEF · 2026
Energy: Sustainable Materials and Design
The motivation of this project was to modify the geometry of high-rise buildings in urban environments, directing and accelerating extreme winds effectively into turbines to generate energy.…
ISEF · 2026
Materials Science
How efficiently a runner uses their energy at a submaximal pace is called an individual's running economy. Current running shoes incorporate a plate made from carbon fiber which results in a…
ISEF · 2026
Translational Medical Science
In the spring of 2025, my aunt tragically passed away from a long and hard-fought battle with breast cancer. My grief inspired me to develop a way to help diagnose breast cancer more efficie…
ISEF · 2026
Mathematics
Urban accessibility optimization is a pressing challenge for sustainable urban development. Classical graph-theoretical methods, such as the Steiner tree problem, provide a framework for con…
ISEF · 2026
Physics and Astronomy
Uncorrected refractive error is the leading cause of vision impairment particularly in low-income regions, due to limited access to diagnostic systems. Current assessment tools including pho…
ISEF · 2026
Biomedical Engineering
OralSense is a smart toothbrush system designed for passive, non-invasive detection of early gingival disease and pre-diabetes risk during routine brushing. It consists of a reusable electro…
ISEF · 2026
Physics and Astronomy
Prior to the first unambiguous discovery in 2011, circumbinary planets (CBPs), planets orbiting two stars or eclipsing binaries (EBs), were considered unlikely to exist due to the perturbati…
ISEF · 2026
Embedded Systems
Roundabouts have become increasingly popular as they offer numerous benefits over traditional intersections for traffic management. Despite this they can be a source of driver confusion due…
ISEF · 2026
Materials Science
The transition to a clean energy is limited by the high cost of green hydrogen production, relying ?on expensive noble metals electrocatalysts. This creates supply chain risks and restricts…
ISEF · 2026
Robotics and Intelligent Machines
This study proposes Purpose And Context Activate Knowledge Efficiently(PANCAKE), a novel structured Chain-of-Thought methodology for enhancing geometric problem-solving in Vision-Language Mo…
ISEF · 2026
Engineering Technology: Statics & Dynamics
In car crashes, the primary cause of fatalities is the sudden forces experienced by the passengers. Considering collision physics, an elongated front bumper would decrease the average force…
ISEF · 2026
Animal Sciences
Traditional begging signals given by the altricial young of birds serve to communicate need to parents and solicit provisions during feeding visits. Such signals often incur costs, like pred…
ISEF · 2026
Computational Biology and Bioinformatics
Accurate pathology billing is crucial for reimbursement, regulatory compliance, and mitigating the $28.8 billion Medicare improper payment crisis amid a growing shortage of medical coders. C…
ISEF · 2026
Translational Medical Science
Most healthcare efforts focus on diagnosis, followed by treatment, and subsequently the post-treatment phase. However, only a limited subset of individuals who prioritize their health pay at…
ISEF · 2026
Animal Sciences
In this project, the major aim is to identify the relationship that exists between the sound type and the level of stress in the dogs. In this project, there are three dogs. Each dog is expo…
ISEF · 2026
Chemistry
Termites, among the most destructive insects, cause nearly US$50 billion in worldwide economic losses annually. For decades, the use of synthetic insecticides such as fipronil has proven hig…
ISEF · 2026
Environmental Engineering
A serious worldwide environmental problem is the increasing generation of agro-industrial and food waste and its improper disposal. Peanuts' global annual production, for example, is approxi…