Browse real student projects, abstracts, and awards.
ISEF · 2026
Embedded Systems
Chemical waste disposal in shared laboratories remains a major safety challenge because it often depends on handwritten labels, incomplete records, and user judgment. These limitations make…
ISEF · 2026
Mathematics
Purpose: A set of two new operators contribute to the development of a new theorem on jumpability that, together with a six-fold characterization of dimensional-expansions, are used to estab…
ISEF · 2026
Chemistry
N-heterocyclic carbenes (NHCs) have emerged as excellent spectator ligands in homogeneous catalysis, especially in transfer hydrogenation reactions. Transfer hydrogenation, the reduction of…
ISEF · 2026
Biomedical Engineering
This project designs anti-cancer peptides that inhibit PDEd, a chaperone regulating KRAS signaling. Using the PDEd crystal structure (PDB: 4JV6), RFdiffusion generated peptide backbones, Pro…
ISEF · 2026
Biomedical Engineering
Elopement/wandering affects nearly 49% of children with Autism Spectrum Disorder (ASD), and 71% of these cases result in fatal outcomes. Existing tracking systems rely on cellular subscripti…
ISEF · 2026
Software Design
Conventional navigation aids for the visually impaired often suffer from estimation errors during non-linear maneuvers and fail to detect hazards obscured by crowds or corners. This study pr…
ISEF · 2026
Animal Sciences
Bees pollinate the flowers of many fruit trees which produce a significant proportion of our food supply. It is therefore important to improve beekeeping practices to produce healthier bees…
ISEF · 2026
Biomedical Engineering
Distal pulse assessment during closed fracture reduction in pre-hospital emergency care is typically performed intermittently and subjectively, leaving windows where vascular compromise may…
ISEF · 2026
Environmental Engineering
This project was designed to tackle the growing problem of the invasive Burmese Python in the Florida Everglades. Since these snakes are hard to find, standard hunting methods did not work w…
ISEF · 2026
Cellular and Molecular Biology
Chlamydia trachomatis is the most common sexually transmitted bacterial infection in the United States. It is frequently asymptomatic, yet can result in severe reproductive complications. Wh…
ISEF · 2026
Biomedical Engineering
Background Heart failure affects 64 million people annually. Transplants are in chronic shortage, especially for pediatric patients. Total artificial heart (TAH) promises a solution; however…
ISEF · 2026
Translational Medical Science
Microalgae are unicellural organisms that are found both in marine and freshwater ecosystems, ranging from tropical water habitats to subpolar areas. They have recently gained attention due…
ISEF · 2026
Plant Sciences
Climate change is triggering soil salinization, which limits crop production, mainly in island communities such as American Samoa. Seed priming is a proven method to boost germination under…
ISEF · 2026
Embedded Systems
Falls are the second leading cause of unintentional injury death worldwide, responsible for over 684,000 deaths annually. Existing solutions leave critical gaps. Preventive approaches like s…
ISEF · 2026
Biomedical and Health Sciences
Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness, characterized by progressive optic nerve damage often without symptoms until significant vision loss occurs.…
ISEF · 2026
Microbiology
An estimated $6 billion USD will be lost in 2026 globally due to disease outbreaks in aquaculture facilities, particularly from Vibrio coralliilyticus, a pathogen that infects corals, fish a…
ISEF · 2026
Environmental Engineering
The lack of control over nitrate and phosphate levels in soil and water is becoming one of the most serious problems facing the Baltic Sea. Eutrophication and uncontrolled nutrient runoff le…
ISEF · 2026
Translational Medical Science
Embryo selection for Frozen Embryo Transfer (FET) is routinely based on subjective parameters. In most modern In-Vitro Fertilization (IVF) labs a quantitative approach for embryo selection i…
ISEF · 2026
Mathematics
One of the central open problems in operator theory and PT-symmetric quantum mechanics is how to construct metric operators explicitly for non-Hermitian operators acting in spaces with an in…
ISEF · 2026
Energy: Sustainable Materials and Design
Hydrogen is a promising clean fuel, yet most global production still relies on fossil fuel intensive processes. Biogenic hydrogen offers a renewable alternative, but natural microbes suffer…
ISEF · 2026
Physics and Astronomy
Current drug design methods treat proteins as rigid structures, failing to capture functional high-energy states. This contributes to 40–50% of clinical-stage drug failures. Mapping continuo…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Autonomous vehicle (AV) research has focused on structured, high-income Western environments, leaving dense, variable developing regions underexplored. This project develops three prototypes…
ISEF · 2026
Software Design
Climate volatility remains a primary obstacle to global food security, subjecting 500 million subsistence farmers to catastrophic financial losses due to the disconnect between traditional p…
ISEF · 2026
Earth and Environmental Sciences
Prescribed burning and mechanical thinning are forest treatments commonly used to alter forest structures for wildfire mitigation. In 2001, the National Fire and Fire-Surrogate (FSS) Study e…
ISEF · 2026
Physics and Astronomy
Purpose: Oil spills cause severe damage to marine life and ecosystems. In this research, we attempted to develop an efficient method that can control oil film movement and therefore manage o…
ISEF · 2026
Computational Biology and Bioinformatics
Computational annotation of protein function remains severely constrained by the vast gap between available sequences and experimentally validated characterizations. Current methods often fa…
ISEF · 2026
Computational Biology and Bioinformatics
HER2 is associated with cancer progression in breast and gastric cancer, and, while HER2-targeted antibody therapy has improved responsiveness, approximately half of patients with HER2-posit…
ISEF · 2026
Translational Medical Science
Cancer remains one of the leading causes of mortality due in part to the limitations of current diagnostic methods, which often rely on single biomarkers and fail to capture the systemic bio…
ISEF · 2026
Biomedical Engineering
Ovarian cancer subtype diagnosis in current clinical practice remains challenging because it relies on expert pathologists and advanced computational infrastructure, which are often unavaila…
ISEF · 2026
Translational Medical Science
Breast cancer recurrence rates reach up to 50%, yet existing clinical tools rely on single modality data or repeated medical check-ups. My model, OncoTwin, is a novel recurrence-risk predict…