Browse real student projects, abstracts, and awards.
ISEF · 2026
Engineering Technology: Statics & Dynamics
Oil well blowouts are a major safety and economic problem in drilling operations, often caused by delays in decision-making during critical situations. In many cases, engineers require signi…
ISEF · 2026
Computational Biology and Bioinformatics
Dementia affects more than 55 million people worldwide, and its prevalence is projected to nearly triple by 2050. A major clinical challenge is identifying individuals who are likely to expe…
ISEF · 2026
Robotics and Intelligent Machines
Coral reefs around the Qatari peninsula are increasingly threatened by rising sea temperatures, pollution, and desalination brine discharge. This project proposes an AI-driven system for rea…
ISEF · 2026
Computational Biology and Bioinformatics
Parkinson disease (PD) remains a progressive neurodegenerative disorder that is characterized by dopaminergic neuronal loss, immune metabolic dysregulation, and chronic neuroinflammation. Th…
ISEF · 2026
Computational Biology and Bioinformatics
Current CRISPR guide design tools rank on single scores without multi-module integration. This project seeks to develop machine learning models to predict optimal CRISPR-Cas9 Guide RNA seque…
ISEF · 2026
Software Design
Our project addresses the knowledge gap between sophisticated and unsophisticated investors. Many unsophisticated investors avoid capital markets because they cannot interpret firms' financi…
ISEF · 2026
Biomedical Engineering
Gliomas remain the deadliest form of brain cancer, with patients surviving one year post-diagnosis on average, 5-year survival rates as low as 5%, and no major treatment advances in the past…
ISEF · 2026
Environmental Engineering
Emergencies like wildfires and industrial accidents threaten public health. Accurate predictions of pollutant dispersion are vital for timely protective actions, but atmospheric models often…
ISEF · 2026
Energy: Sustainable Materials and Design
As fossil fuels have been sent back to the head of the line for depletion, there is a need to continue to find alternative fuels. Algae has become a nuisance. In reaction to increased freque…
ISEF · 2026
Behavioral and Social Sciences
Large language models (LLMs) like ChatGPT, Claude, Gemini, and DeepSeek increasingly influence how people access and interpret political information, raising concerns that they may subtly sh…
ISEF · 2026
Physics and Astronomy
This project presents an in-line lens-free digital holographic imaging system capable of single-frame 3D reconstruction. I used a 532 nm monochromatic source to illuminate the sample, and th…
ISEF · 2026
Biomedical Engineering
This project centers around the ultimate goal of making cancer research more affordable and accessible to labs and students around the world. Cancer cells that grow in low-oxygen environment…
ISEF · 2026
Biochemistry
Water pollution by phenolic compounds and heavy metals poses a significant threat to aquatic ecosystems, creating a need for rapid, low-cost methods to assess environmental toxicity. Tyrosin…
ISEF · 2026
Robotics and Intelligent Machines
Approximately 2.1 million people in the U.S. live with limb loss, with about 36% experiencing depression. Conventional non-invasive prosthetic control relies on electromyography (EMG), which…
ISEF · 2026
Robotics and Intelligent Machines
Due to the need for unsafe or costly data collection to train a policy in the real world, sim-to-real transfer is the most common approach: learning a policy in simulation and deploying it i…
ISEF · 2026
Physics and Astronomy
Gravitational waves (GWs) are ripples in spacetime produced by massive astronomical events such as compact binary coalescences (CBCs) involving black holes and neutron stars. Although matche…
ISEF · 2026
Earth and Environmental Sciences
Peatland fires are among the most detrimental types of fires toward global warming, and are capable of releasing 10 times more carbon per hectare into the atmosphere than typical forest fire…
ISEF · 2026
Biomedical and Health Sciences
Protamine 1 (PRM1) and protamine 2 (PRM2) are essential for packaging sperm DNA and maintaining genome stability during spermatogenesis. Changes in their expression levels are associated wit…
ISEF · 2026
Environmental Engineering
This study presents the design, implementation, and validation of a low-cost autonomous water quality monitoring and forecasting system integrating embedded IoT hardware with an adaptive mac…
ISEF · 2026
Computational Biology and Bioinformatics
Agricultural pesticide use remains substantial, increasing chemical exposure, environmental burden, and production costs. U.S. farms spent $21.7 billion on agricultural chemicals in 2024. Be…
ISEF · 2026
Biomedical Engineering
The current nurse to patient ratio in medical-surgical units spans from 1:4 to 1:6, however in long-term care units, this number can range anywhere from 1:15 to 1:30. Additionally, instances…
ISEF · 2026
Computational Biology and Bioinformatics
Enzymes are widely used across healthcare, textiles, and environmental technologies, requiring optimization through enzyme engineering. Traditional approaches rely on wet-lab trial-and-error…
ISEF · 2026
Translational Medical Science
Neurodegenerative diseases, including Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI), are typically diagnosed after 50-80% neuronal loss, reflecting a critical failure of early…
ISEF · 2026
Computational Biology and Bioinformatics
Epilepsy is a neurological disorder characterized by recurrent seizures, and affects nearly 50 million people, causing ~140,000 deaths worldwide annually. Many of these deaths could be preve…
ISEF · 2026
Translational Medical Science
Visual impairment (VI) affects 2.2 billion people worldwide, and 1 billion cases are preventable with early diagnosis. Retinal diseases are preventable causes of VI. Clinical Decision Suppor…
ISEF · 2026
Computational Biology and Bioinformatics
Background: Rupture of cerebral aneurysm, an abnormal bulging of the arterial wall, can lead to brain hemorrhage and stroke. Endovascular surgical treatment is highly invasive and poses sign…
ISEF · 2026
Biomedical Engineering
Respiratory exacerbations are often detected only after symptoms become severe, limiting opportunities for early intervention. Current monitoring systems rely on clinic-based devices or sing…
ISEF · 2026
Biomedical and Health Sciences
Despite advances in immunotherapy, up to 60% of melanoma patients do not respond to treatment. Emerging evidence suggests that physical exercise enhances anti-tumor immunity; however, the mo…
ISEF · 2026
Environmental Engineering
Early wildfire detection and prediction systems based on machine learning have typically relied on a single type of data, either meteorological data or satellite imagery, limiting their accu…
ISEF · 2026
Computational Biology and Bioinformatics
Nearly 50% of human IVF embryos arrest before reaching the blastocyst stage, yet the molecular mechanisms causing this failure remain poorly understood. Current literature examines omics in…