Browse real student projects, abstracts, and awards.
ISEF · 2026
Translational Medical Science
Translational research on neurodegenerative diseases is constrained by the cost, long timelines, and variability of generating mature neuronal assay substrates, which also limits scalable pr…
ISEF · 2026
Biomedical and Health Sciences
Psychiatric disorders, including schizophrenia (SCZ) and bipolar disorder (BD), are leading causes of global disability. The development of effective therapeutics is challenged by the comple…
ISEF · 2026
Translational Medical Science
In rural areas of the world, such as villages in India & Africa, inhabitants lack access to medical infrastructure. Due to this, early disease diagnosis is not possible, as early symptoms fo…
ISEF · 2026
Physics and Astronomy
Vertical vibration can levitate a liquid layer above an air cushion. As the driving acceleration increases, the system transitions through three regimes: Rayleigh-Taylor instability at the l…
ISEF · 2026
Chemistry
This project investigates Liesegang-type self-organization phenomena for the development of functional biomaterials for bone regeneration and controlled drug delivery. The experimental proce…
ISEF · 2026
Cellular and Molecular Biology
This project aims to link the cellular heat stress response of Montipora capitata to its biological immortality. The amortality of this species is attributed to alternative methods of telome…
ISEF · 2026
Microbiology
Burkitt's Lymphoma is an aggressive B-cell malignancy associated with Epstein-Barr virus (EBV) infection. Over 95% of the world's population is persistently infected by EBV. While current tr…
ISEF · 2026
Biomedical and Health Sciences
Extracorporeal Membrane Oxygenation (ECMO) is a life-saving cardiopulmonary support system for patients with severe cardiac and/or respiratory failure. Its use has increased substantially si…
ISEF · 2026
Technology Enhances the Arts
Current speech-to-sign language translation systems cannot express the emotions behind the words, making it difficult for deaf and hard-of-hearing individuals to fully grasp the speaker's tr…
ISEF · 2026
Behavioral and Social Sciences
Benchmarks often fail to capture true large language model (LLM) trustworthiness, as models behave differently under evaluation than in real-world deployment. This research introduces a syst…
ISEF · 2026
Chemistry
The purpose of this experiment was to test the spread and droplet size of a drone application with and without a chemical surfactant adjuvant. It is hypothesized, the water with the chemical…
ISEF · 2026
Microbiology
CRISPR–Cas systems enable bacteria to defend against viral infection through RNA-guided nucleases and accessory proteins, though the functions of many accessory components remain unclear. Th…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Flash flooding is one of the deadliest weather events, taking over 5,000 lives each year. Traditional flash flood detection systems are often inadequate: they are expensive, require frequent…
ISEF · 2026
Biomedical Engineering
In 2025, the American Cancer Society reported 2.1 million Americans were diagnosed with cancer, which is the leading cause for 1 in 6 deaths. This can largely be attributed to late diagnoses…
ISEF · 2026
Materials Science
Despite its accessibility and geometric versatility, polymer additive manufacturing remains limited in industrial use due to the inherent structural and chemical vulnerabilities of polymers.…
ISEF · 2026
Embedded Systems
Pressure injuries are a serious health problem caused by staying in the same position for long periods. They reduce blood flow to tissues and are difficult and expensive to treat. In hospita…
ISEF · 2026
Behavioral and Social Sciences
Mental health affects all aspects of life, it's a significant factor that if overlooked could cost lives and mission success particularly in space exploration. Mental health is a critical fa…
ISEF · 2026
Translational Medical Science
Pancreatic ductal adenocarcinoma (PDAC) ranks 10th in US cancer incidence, yet it causes more deaths per year than breast cancer, ranked 1st, a disparity largely driven by complications rega…
ISEF · 2026
Computational Biology and Bioinformatics
Autism spectrum disorder (ASD) is a neurodevelopmental condition affecting many areas of life. Resting-state functional MRI (rs-fMRI) measures functional connectivity between brain regions a…
ISEF · 2026
Translational Medical Science
Background: Treatment of Multiple Myeloma (MM) with bispecific antibodies (bsAb) results in an increased risk of infection, and predicting this risk is a significant unmet need. Aim: Develop…
ISEF · 2026
Cellular and Molecular Biology
Oral squamous cell carcinoma (OSCC) accounts for over 90% of oral cancers, with 5-year survival rates below 60% due to late-stage diagnosis. Current diagnostic approaches rely on invasive su…
ISEF · 2026
Materials Science
Metal-organic frameworks (MOFs) are highly tunable nanomaterials with potential in targeted immunotherapy and biological interfaces; however, the vast number of possible metal frameworks lim…
ISEF · 2026
Earth and Environmental Sciences
Known as the “rainforests of the sea” coral reefs support over 1 billion people. Yet the rising ocean temperatures have driven increasingly frequent coral bleaching events, threatening reefs…
ISEF · 2026
Translational Medical Science
Abstract Parkinson's disease often affects voice and speech years before motor symptoms become clinically evident, and clinical diagnosis can take years to confirm. Machine learning applied…
ISEF · 2026
Energy: Sustainable Materials and Design
Solar water evaporation (SWE) outstands as a promising method to solve the global freshwater shortage due to its lower cost, green and sustainable. Semiconductors photothermal materials (SPM…
ISEF · 2026
Translational Medical Science
The purpose of this investigation was to develop a machine learning model capable of predicting early vocal patterns associated with glottic carcinoma risk using acoustic biomarkers and life…
ISEF · 2026
Animal Sciences
Neonatal Maladjustment Syndrome (NMS), also known as dummy calf syndrome, affects newborn calves by limiting their alertness, ability to stand, nurse, and bond with their mother. The researc…
ISEF · 2026
Physics and Astronomy
This project evaluated the ability of laboratory-scale permanent magnets and a battery-powered electromagnet to generate magnetic pressure and compared their capacity to approach the pressur…
ISEF · 2026
Materials Science
Slips, Trips, and Falls (STFs) are major sources of accidents among various populations. About 38 mill falls happen each year in the US alone, with more than 50,000 associated with mobility…
ISEF · 2026
Energy: Sustainable Materials and Design
Can you imagine clothing made from seaweed? The textile/fashion industry discards in excess of 90 tons of textile waste annually. The industry is trying to become more sustainable by develop…