Browse real student projects, abstracts, and awards.
ISEF · 2025
Animal Sciences
An owl wing is a mechanical marvel built for silent flight. The posterior margin of each feather has trailing edge fringe which is key to reducing air vortexes resulting in dramatically quie…
ISEF · 2025
Cellular and Molecular Biology
Multiple myeloma (MM) is an incurable cancer of malignant plasma cells with a 5-year survival of 54%. Immunotherapy has recently emerged as a highly promising modality to treat MM. CD8+ T-ce…
ISEF · 2025
Earth and Environmental Sciences
Climate change comes in many forms, sometimes from unexpected sources. Manure management facilities are some of the most overlooked, yet consequential facilitators of climate change, contrib…
ISEF · 2025
Earth and Environmental Sciences
Schistocerca gregaria (desert locust) is the world's most destructive migratory pest and a serious threat to food security. Existing locust-control tools use real-time field data to monitor…
ISEF · 2025
Physics and Astronomy
The internal kinematics of massive red supergiant branch (RGB) and oxygen-rich and carbon-rich asymptotic giant branch (AGB) stars in the Magellanic Clouds have been modeled to examine the t…
ISEF · 2025
Systems Software
Millions of people with paralysis struggle to use everyday technology due to limited motor function. In the U.S. alone, over 5.3 million individuals—about 1.7% of the population—live with pa…
ISEF · 2025
Robotics and Intelligent Machines
Over the past 5 years, the United States recorded over 25,000 fatal work injuries (AFL-CIO, 2023). Industries like scientific laboratories, recycling and manufacturing facilities are especia…
ISEF · 2025
Biomedical Engineering
The objective of this project is to develop a low-cost, portable, multi-sensor device for accurate early detection of multiple cancers, designed for home use and resource-limited settings. T…
ISEF · 2025
Materials Science
The increasing reliance on optoelectronic devices in communication, sensing, and display technologies has driven the search for alternative materials that are cost-effective, scalable, and h…
ISEF · 2025
Computational Biology and Bioinformatics
Lung cancer is the most commonly diagnosed cancer worldwide and the leading cause of cancer-related deaths. It is difficult to diagnose accurately, especially at an early stage. No tradition…
ISEF · 2025
Robotics and Intelligent Machines
Lung cancer, the leading cause of cancer-related deaths globally, continues to face limited clinical adoption of machine learning model analysis for diagnosis due to the absence of an integr…
ISEF · 2025
Robotics and Intelligent Machines
Malaria is one of the top three most prevalent diseases in Ghana, with 5.2 million cases of malaria in 2022 alone, according to Ghana Health Service data. Light microscopy is the current bes…
ISEF · 2025
Translational Medical Science
Purpose: Patients with breast cancer (BC) who undergo neoadjuvant therapy (NAT) before surgery and achieve a pathologic complete response (pCR) after NAT have a low rate of recurrence. Howev…
ISEF · 2025
Computational Biology and Bioinformatics
Inflammatory diseases affect billions of patients worldwide. Receptor for Advanced Glycation End products (RAGE) has been identified as a promising target for many inflammatory diseases, inc…
ISEF · 2025
Animal Sciences
Parkinson's disease (PD), the second most common and fastest-growing neurodegenerative disorder affecting over 10 million people worldwide, is characterized by progressive neurodegeneration…
ISEF · 2025
Earth and Environmental Sciences
Coral reefs stand as the ocean's last line of defense, a living barrier vital to the marine ecosystem, supporting approximately 25% of its biodiversity, and providing additional benefits to…
ISEF · 2025
Plant Sciences
In today's world, research about growing plants in space is being done against challenges in disoriented directions and slow growth rate of radicles. While plants on Earth shoot roots downwa…
ISEF · 2025
Mathematics
Make24 is a classic game where players compete to be the fastest to get to 24 using 4 integers between 1 and 10 inclusive. In the generalised version of this game, one is given k not necessa…
ISEF · 2025
Mathematics
Clinical trials often utilize composite endpoints to provide a comprehensive evaluation of a treatment’s effects by combining multiple related outcomes into a single measure. While tradition…
ISEF · 2025
Chemistry
When AgNO3 and sodium alginate are mixed, cross-linking occurs by the cation Ag+ and anion Cl-, which can produce an AgNPs-SA gel. Through this research, it was found out that when this film…
ISEF · 2025
Computational Biology and Bioinformatics
Mangroves play a crucial role in coastal protection, biodiversity support, carbon sequestration, and water purification. However, between 1996 and 2020, the Philippines lost 7,934 hectares o…
ISEF · 2025
Biomedical Engineering
One of the biggest hurdles to Stem Cell Therapies' clinical applications has been the difficulty in delivering stem cells safely and retaining them at the target site without migrating uncon…
ISEF · 2025
Earth and Environmental Sciences
The large amounts of CO2 generated by human activities results in an increase in ocean acidity on a global scale (Hill, 2018). The ability to determine long-term open ocean acidification tre…
ISEF · 2025
Mathematics
For the last 20 years, many researchers have explored divisibility properties of integer sequences arising from combinatorial structures. In particular, binomial coefficients have been the s…
ISEF · 2025
Cellular and Molecular Biology
Our project determined that resazurin, a synthetic fluorescing agent originally used as a bioburden detector, is a practical fluorescing agent for quantifying NADH in cell-free reactions. We…
ISEF · 2025
Materials Science
This study investigates the impact of environmental temperature changes on the mechanical properties of two plastic polymers: polyethylene terephthalate glycol (PETG) and poly(3-hydroxybutyr…
ISEF · 2025
Systems Software
This research project explores a novel media service platform designed to optimize video streaming. Modern media delivery faces two key challenges: inter-server video transfer inefficiencies…
ISEF · 2025
Translational Medical Science
Each year, 1.9 million people worldwide are diagnosed with colorectal cancer, and early detection of cancerous polyps is crucial for treatment. Endoscopic imaging is a critical part of ident…
ISEF · 2025
Environmental Engineering
The vulnerability of water bodies to human activities leads to a widespread problem of degradation of these environments and denounces the finitude of potable water in many regions of the Ea…
ISEF · 2025
Behavioral and Social Sciences
Chronic stress, doomscrolling and digital addiction contribute to declining memory and attention in children. These factors negatively affect cognitive development, making it essential to ex…