Browse real student projects, abstracts, and awards.
ISEF · 2026
Computational Biology and Bioinformatics
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer with a 90% mortality rate. Standard treatments such as surgery and chemotherapy show high recurrence rates of ~85% due to PD…
ISEF · 2026
Computational Biology and Bioinformatics
Sickle cell disease (SCD) remains a major global health challenge, with no widely accessible targeted cure and most existing therapies focused on symptom management or partial disease modifi…
ISEF · 2026
Software Design
Misdiagnosis remains a critical challenge in dental radiography. In a study where 151 Egyptian dental professionals were surveyed, 94.7% identified it as urgent issue, with over 90% reportin…
ISEF · 2026
Embedded Systems
Paralysis afflicts 15.4 million people globally, growing by 0.5 million annually, with an additional 2.5 million Americans experiencing severe arm mobility impairment, with prosthetics costi…
ISEF · 2026
Biomedical Engineering
Purpose: Millions of deaths are preventable annually, with timely emergency care (WHO). Yet in real life emergencies; lives are lost since help doesn't arrive within critical “golden time”.…
ISEF · 2026
Earth and Environmental Sciences
My project is a Chesapeake Bay case study simulation built using an existing Lagrangian tracking model, driven by real National Oceanic and Atmospheric Association (NOAA) current and wind da…
ISEF · 2026
Earth and Environmental Sciences
Oil spills are among the most serious environmental threats. They remain difficult to control, and current remediation methods either disperse oil into water or use chemically aggressive tre…
ISEF · 2026
Software Design
Passwords are failing. Stolen credentials are now responsible for over 88% of online attacks, and systems are unable to detect when an attacker bypasses a login screen or accesses an unatten…
ISEF · 2026
Biomedical Engineering
Currently 250,000 to 390,000 Americans are estimated to live with a spinal cord injury. United Spinal Association (2025) states that the number grows by 18,000 approximately every year. That…
ISEF · 2026
Mathematics
Two - qubit gates drive the power of quantum circuits, but finding new universal gates remains challenging. In this study, we developed an evolutionary computational framework to systematica…
ISEF · 2026
Translational Medical Science
Oral cancer therapeutics often fail due to drug degradation within the gastrointestinal tract before systemic absorption. This study evaluated the gastrointestinal stability of a carbon nano…
ISEF · 2026
Energy: Sustainable Materials and Design
Growing up in Iraq, infrastructure gaps and an unstable grid cause persistent power outages that directly impact quality of life. To meet demands, these regions tend to rely on environmental…
ISEF · 2026
Cellular and Molecular Biology
The mechanistic target of rapamycin complex 2 (mTORC2) regulates cell motility and is commonly assessed by AKT phosphorylation at S473. It remains unclear whether distinct chemoattractants p…
ISEF · 2026
Microbiology
Filamentous fungi offer promising solutions for upcycling industrial food byproducts. Neurospora intermedia, used for centuries in Western Java to ferment red oncom from a byproduct of soy m…
ISEF · 2026
Physics and Astronomy
This project aimed to produce a Type II superconductor through substitution doping of Zirconium (Zr) into the crystalline structure of Tantalum Chromium Phosphorus (TaCrP), which has never b…
ISEF · 2026
Cellular and Molecular Biology
Cancer genomic alterations often create unique vulnerabilities that can be exploited for precise treatment. Inhibitors exploiting synthetic lethal relationships have recently shown clinical…
ISEF · 2026
Animal Sciences
Genetic variation plays a key role in individual patient outcomes, particularly with age due to physical vulnerability. Rho1 is a gene in Drosophila melanogaster encoding proteins in the fam…
ISEF · 2026
Behavioral and Social Sciences
Reading immersion (flow) significantly enhances enjoyment and satisfaction during novel reading, yet its neural mechanisms and relationship to event segmentation remain poorly understood. Ev…
ISEF · 2026
Translational Medical Science
Elevated atmospheric CO2 (atmCO2) is a persistent operational challenge in human spaceflight, where crew exhalation and limited ventilation lead to CO2 accumulation within the cabin. As a re…
ISEF · 2026
Biomedical and Health Sciences
Glioblastoma multiforme (GBM) remains the most aggressive primary brain tumor, with a median survival of 12–15 months despite multimodal therapy. Identifying compounds that selectively induc…
ISEF · 2026
Animal Sciences
Benzodiazepines and antidepressants are used primarily in the treatment of anxiety, yet often come with negative side effects. Selank is an anxiolytic peptide approved for usage in Russia an…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Magnetohydrodynamic thrusters produce silent, propellorless thrust, but they have significant drawbacks that restrict their commercial use. Conduction based MHD, which sends an electric curr…
ISEF · 2026
Cellular and Molecular Biology
Americans use an average of 1.6 straws per day, PFAS, are present in both plastic and paper straws, contributing to the increased health issues related to microplastics and PFAS. Several stu…
ISEF · 2026
Biomedical and Health Sciences
Fragrance products have been on the rise in popularity recently. Volatile organic compounds (VOCs), which are toxic airborne chemicals, have shown to be most prominent in the product's ingre…
ISEF · 2026
Environmental Engineering
Moyle (1944) found that lakes with high sulfate levels do not contain wild rice. In wetland soil with low oxygen concentrations, bacteria convert sulfate from municipal or industrial sources…
ISEF · 2026
Biomedical and Health Sciences
Three-dimensional (3D) cell culture is an emerging technique that allows cells to grow in a way that more closely resembles how they exist in the body. Unlike traditional two-dimensional (2D…
ISEF · 2026
Animal Sciences
Morphogen gradients determine distinct cell fate within tissues, and it has previously been thought that the cells affected by this determination are static. However, cells usually move duri…
ISEF · 2026
Earth and Environmental Sciences
It's been hypothesized that carbonaceous chondrite meteorites can transport compounds crucial to planetary habitability. Meteorites generate hydrothermal systems through impact energy dissip…
ISEF · 2026
Biomedical and Health Sciences
Triple negative breast cancer is notoriously difficult to treat bacause it lacks estrogen receptors, progesterone receptors, and HER2 protein that drive the majority of breast cancers and th…
ISEF · 2026
Physics and Astronomy
Aerodynamics is heavily dependent on the four main forces of flight, weight, lift, thrust, and drag. Drag heavily impacts the aerospace industry's ability to create faster and more effective…