Browse real student projects, abstracts, and awards.
ISEF · 2021
Plant Sciences
The scarcity of water and land resources, the use of environmentally harmful substances, and food production that is increasingly insufficient to meet the demands of an ever-growing populati…
ISEF · 2021
Plant Sciences
The global supply chain possesses constant potential threats from political disruption, climate change, health emergencies, and trade conflicts. Under the supply chain network, the food sect…
ISEF · 2021
Engineering Mechanics
After the success of the previous Hydroloop model, there were still two major problems that needed solving: a lack of consistency and efficiency, both of which stemmed from the rudimentary c…
ISEF · 2021
Chemistry
Nanotechnology is a rapidly growing, new branch of science. Nanomaterials reveal that a vast majority of research is concentrated on synthesis, development and analysis of gold and silver na…
ISEF · 2021
Biomedical and Health Sciences
Elevated homocysteine (Hcy), i.e. hyperhomocysteinemia (HHcy), is a risk factor for Alzheimer’s disease (AD). Accumulation of amyloid beta (Aß) aggregates is a major hallmark of AD. One of t…
ISEF · 2021
Biomedical and Health Sciences
The overall prevalence of Diabetes Mellitus is rapidly increasing as a result of an ageing population, urbanization and lifestyle changes. Generally, drugs with different chemical structures…
ISEF · 2021
Cellular and Molecular Biology
Lung adenocarcinoma (LUAD) accounts for forty percent of all lung cancer cases in the United States. Treatment currently focuses on surgery and chemotherapy but survival rates remain lower t…
ISEF · 2021
Plant Sciences Fourth Award
This project is the beginning of a gene identification and characterization project with implications in potential genetically engineerable traits for bush crops. We have found a candidate g…
ISEF · 2021
Physics and Astronomy
One of the leading problems plaguing optical asteroid research is the presence of albedo variegations: areas on the surface of the asteroid that reflect light incongruously due to differing…
ISEF · 2021
Translational Medical Science
Neuroblastoma has remained as the most severe cancer amongst young children (0-1 y/o). The current treatments for this disease include chemotherapy and radiation therapy, both of which have…
ISEF · 2021
Computational Biology and Bioinformatics
BETA-site amyloid precursor protein cleaving enzyme 1 (BACE1) has medical significance for forming a drug target to treat Alzheimer's disease (AD). The activity of BACE1 toward amyloid precu…
ISEF · 2021
Behavioral and Social Sciences Fourth Award
Depression is a leading cause of death and disability with more than 264 million people of all ages suffering from the disorder worldwide. Understanding how brain function is altered in depr…
ISEF · 2021
Systems Software Third Award
Quantum computing is an emerging technology that, with its exponential computational speedup, will allow us to solve a new level of hard problems. From rapid vaccine development, efficient d…
ISEF · 2021
Translational Medical Science Second Award
Atrophic macular degeneration (AMD) affects 200 million people worldwide. There is no FDA-approved therapy for this disease, the leading cause of irreversible blindness among people over 50.…
ISEF · 2021
Earth and Environmental Sciences
Plastic is an indispensable and persistent material used in everyday life. Plastic contamination is found in terrestrial and marine environments which can be fragmented into microscopic micr…
ISEF · 2021
Translational Medical Science
A predictive gene biomarker helps determine which patients are most likely to benefit from a specific treatment option. The probability of survival from a treatment can greatly depend on if…
ISEF · 2021
Biomedical and Health Sciences
Rheumatoid arthritis (RA) and osteoarthritis (OA) are distinct joint diseases presenting unique pathophysiologies. Because of the similar symptoms that RA and OA present, such as arthralgia,…
ISEF · 2021
Biochemistry
The aromatic amino acid Tyrosine was synthesized using three types of clays, water, heat, and a few common compounds. However, initial efforts to identify Tyrosine were stymied by the sole u…
ISEF · 2021
Earth and Environmental Sciences
Hawaii is a biodiversity hotspot with high levels of endemism. Many endangered species are vulnerable to climate change. The project's purpose is to determine the habitats threatened by sea-…
ISEF · 2021
Earth and Environmental Sciences
The study of invertebrate paleontology has been of great significance in the understanding of extant species and their evolutionary patterns. Paleontologists spend months in harsh conditions…
ISEF · 2021
Environmental Engineering First Award
An estimated 2.5 billion people lack access to improved sanitation and 780 million people to improved water sources worldwide. This is due to the high expense and difficulty of traditional f…
ISEF · 2021
Plant Sciences
Dioscorea bulbifera, (air potato) is an invasive vine that has a smothering effect on native vegetation in Florida as well as other southeastern states in the U.S. In 2012, a beetle (Lilioce…
ISEF · 2021
Biomedical Engineering
An image analysis measurement system was developed for rehabilitating patients on a prescribed exercise regime after joint injury or joint surgery. The relationship between rehabilitation ex…
ISEF · 2021
Plant Sciences
The promotion of local fruit production to enhance community economic development and also to solve food security problem is of prime concern. Cluster fig (Ficus racemosa), a polycarpic plan…
ISEF · 2021
Cellular and Molecular Biology Third Award
Down syndrome (DS) is the most common genetic disorder in humans. It is known that trisomy of chromosome 21 causes DS, but how this chromosomal gain produces the complex DS phenotype, includ…
ISEF · 2021
Biomedical Engineering
As the effort for SARS-CoV-2 vaccine development continues, characterization of SARS-CoV-2 immune memory has indicated that the Spike (S) protein, the target of most SARS-CoV-2 vaccines, eli…
ISEF · 2021
Translational Medical Science
The tumor immune microenvironment (TIME) of breast cancer is a known source of tumor heterogeneity and it has been increasingly recognized as having a role in the course of disease. In the p…
ISEF · 2021
Cellular and Molecular Biology Fourth Award
Non-small cell lung carcinoma (NSCLC), accounting for the majority of lung cancer cases, has become a high-studied topic in the field of immunotherapeutics. While there are treatment options…
ISEF · 2021
Biomedical and Health Sciences
Aging is a major contributor towards many diseases. Two examples of these diseases would be Cancer and Alzheimer’s disease, two leading causes of death within America. Aging is a synergy and…
ISEF · 2021
Behavioral and Social Sciences
During the COVID-19 pandemic, adolescents have played a major role in the spread and mitigation of the virus. While adolescents have much lower mortality rates, they are equally prone to con…