ISEF · 2022
Coding for STEM Education
Systems Software
Disparities in rural and urban education can be sourced from many different factors, whether it be funding, location, or faculty availability. However, even with these disadvantages, many fi…
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ISEF · 2022
Co-Ferrite Modified Hematite Films for All-Day Active Photo-Electrocatalyst Electrode in Water Splitting
Energy: Sustainable Materials and Design Third Award
In the modern era of the technological revolution, most energy needs are fulfilled from burning fossil fuels. They are not only depleting very fast but have adverse impacts on our environmen…
ISEF · 2022
Cognitive Profiling and Personalized Therapy Recommendation for Dementia Through a Language-Aware Multi-Model Artificially Intelligent System
Behavioral and Social Sciences Third Award
Over 55 million people currently have dementia with an expected rise to 135 million cases by 2050. Despite having over 82% of primary care physicians in the frontlines of dementia care, only…
ISEF · 2022
Col-IV: An Indicator of Vascular Formation and Pericyte Recruitment
Animal Sciences
Stroke, a leading cause of disability, causes brain tissue to become abruptly hypoxic. Acute hypoxia stimulates destabilization of the extracellular matrix (ECM) and damages the cellular mic…
ISEF · 2022
Collective Behavior and Coastal Health: How Individual Personality Influences Population Mortality in a Marsh Ecosystem Predator-Prey Interaction
Animal Sciences Fourth Award
Salt marsh ecosystems provide a multitude of critical ecosystem services and are dominated by the cordgrass, Spartina alterniflora. Littoraria irrorata, the marsh periwinkle, is an important…
ISEF · 2022
Combating Antibiotic-Resistant Bacteria With Leptospermum Honey-Incorporated Calcium Alginate Dressing
Biomedical Engineering
Over the past several decades, excessive antibiotic use has led to the rapid development of antibiotic-resistant bacteria. The decreasing effectiveness of antibiotics in managing chronic wou…
ISEF · 2022
Combating Disease in Under-Resourced Areas: Synthetic Degradation as a Method to Low-Quality Image Classification
Systems Software Third Award
All disorders, particularly progressive and degenerative ones, are more severe in under-resourced areas due to lower access to diagnostic resources. A delayed or inaccurate diagnosis can be…
ISEF · 2022
Comparative Analysis of the Effectiveness of Polyethylene, Cetyl Alcohol (Hexadecan-1-ol) and Shade Balls in Preventing Evaporation of Water and Its Effect on Water Quality
Earth and Environmental Sciences
Water is the most important natural resource. There are many ways to prevent water evaporation, including the recently used “Shade Balls.” These four inch polyethylene balls cover reservoirs…
ISEF · 2022
Comparative Analysis on the Effect of the Dosage of Hydrogen Peroxide in the Germination Process in Legumes Phaseolus vulgaris L. (Pink and Red Bean Variety) and Cicer arietinum (Chickpea)
Plant Sciences
The soil is the most important resource in agriculture. However, every day it is found in poor conditions, or even available. The population growth and change in consumption patterns force u…
ISEF · 2022
Comparative Research of Image Processing Algorithms for Segmentation of Natural Water Bodies in Satellite Images
Robotics and Intelligent Machines
Abrupt climate changes around the world, coupled with the rapid growth of population, are leading to a critical shortage of water, thus creating a need for reliable, up-to-date, and efficien…
ISEF · 2022
Comparing Neural Network Strategies to Label Tricuspid Valve on MRI Images
Biomedical and Health Sciences
Heart failure is the number one leading cause of death globally (17.9 million deaths annually). Earlier diagnosis is ideal for the implementation of treatment regimens for the patient. Diagn…
ISEF · 2022
Comparing the Efficiency of Novel Point-Of-Care, Low-Cost Neural Networks in Identifying Specific Stages of Diabetic Retinopathy Across a Limited Retinal Dataset
Systems Software
Diabetic retinopathy is a complication, caused by a history of diabetes, that slowly deteriorates a person’s vision and severely impacts those in low-income areas due to a lack of available…
ISEF · 2022
Comparing the Genomic and Functional Properties of Phage BangNhom and Other Phages To Test Medical Capabilities for Tuberculosis
Computational Biology and Bioinformatics
Tuberculosis (TB) is a type of mycobacterial infection that has a very high mortality rate if it is left untreated. Bacteriophages are a type of virus that infects and replicates only in bac…
ISEF · 2022
Comparing the Leidenfrost Effect on Distilled Water and Ethanol
Physics and Astronomy
The Leidenfrost phenomenon is the term given to the phenomena observed when small quantities of a liquid are placed on an extremely hot surface. The purpose of this project is to investigate…
ISEF · 2022
Comparing the Polymerization of Casein Protein Using Homogenized Bovine Milk Types
Biochemistry
Casein-based plastics could be a solution to the petroleum-based plastics that are plaguing the world. Using renewable and common monomers that are renewable and available around the world,…
ISEF · 2022
Comparison of Ambient Air Pollutants in Varying Income Tracts Using a Constructed, Portable Device That Precisely Measures Ambient Air Concentrations (PAQMS)
Environmental Engineering
Almost the entire global population breathes unhealthy air (World Health Organization, 2022) and it disproportionately affects lower-income communities (World Health Organization, 2022). Som…
ISEF · 2022
Comparison of Commercial and Natural Disinfectants and Their Effect on Microorganisms
Microbiology
The current epidemiological situation has overwhelmed us with information about the prevention of Covid-19 and, within this, also about the necessary hygiene habits, e.g. in connection with…
ISEF · 2022
Comparison of Skin Moisturizers and Antibiotic Ointments in the Ability To Inhibit Bacteria
Biomedical and Health Sciences
The objective was to compare antibiotic ointments and skin moisturizers’ ability to inhibit bacteria. The hypothesis was antibiotic ointments will inhibit bacterial growth more than skin moi…
ISEF · 2022
Comparison of Struvite and Chlorella vulgaris Solution to Phosphorus Water Pollution
Chemistry
Agricultural fertilizer runoff contains high phosphorus concentrations, which directly correlates with eutrophication and, ultimately, has an adverse effect on ecosystems and organisms. Ofte…
ISEF · 2022
Complex Combination of Diabetes and Covid-19: Role of Glycolytic Inhibitors in the Treatment
Biomedical and Health Sciences
The purpose of this project is to identify the role of glycolytic inhibitors as repurposed drugs for the cure of Covid-19 through virtual screening and test their efficacy against the inhibi…
ISEF · 2022
Computational Analysis of SARS-CoV-2 Variants' Binding With Vertebrate ACE2
Computational Biology and Bioinformatics
This study explored the effect of changes in the spike protein across SARS-CoV-2 variants (wild-type, Alpha, Beta, Gamma, and Omicron) on the initial binding interactions with American mink…
ISEF · 2022
Computational Analysis of the Cystic Fibrosis Lung Microbiome and Development of a Non-Toxic Quorum Quenching Cocktail Therapy To Inhibit Multispecies Biofilm Proliferation
Microbiology First Award
Bacterial biofilms account for 80% of all chronic microbial infections. ESKAPE pathogens form dense, multispecies biofilms that are resistant to most antibiotics. In this project, a combinat…
ISEF · 2022
Computational Analysis of the Rhizosphere Metagenome and a Wet Lab Approach To Derive an Optimal Strategy for Heavy Metal Remediation in situ
Plant Sciences Fourth Award
The Environmental Protection Agency reports nearly half a million contaminated sites throughout the U.S. Rhizoremediation is a promising solution to this global public health concern, as cur…
ISEF · 2022
Computational and Experimental Design of a Novel Acetylcholinesterase Inhibitor: Silanediols for Alzheimer's Disease Treatment
Biochemistry Fourth Award
Alzheimer’s Disease (AD) is currently the sixth leading cause of death. The Food and Drug Administration (FDA) has only approved six AD drugs, all of which are associated with severe side ef…
ISEF · 2022
Computational Assessment of Macrocyclic Host-Guest Ion-Dipole Interactions With Negative Pores
Chemistry Third Award
Macrocycles are increasingly studied in supramolecular host-guest chemistry due, in part, to their molecular recognition and binding capabilities. Herein, a computational study which employe…
ISEF · 2022
Computational Design, Docking, and Analysis of Novel Aryl Sulfone Compounds as Potential NNRTIs
Biochemistry Second Award
HIV affects millions of people globally. Due to the high mutation rate of HIV, it is important that novel drugs are constantly found to combat new strains. NNRTIs are allosteric inhibitors t…
ISEF · 2022
Computational Method of Analyzing Genetic and Epigenetic Information for Predicting Mutations in Colorectal and Pancreatic Ductal Adenocarcinoma Cancers
Computational Biology and Bioinformatics
This study investigates the carcinogenesis of cancer drivers by leveraging epigenetics, genomics, known biomarkers, and phenotypic information creating an algorithm identifying tumor suppres…
ISEF · 2022
Conquering Chaos: Can Engineering Design Be Applied To Prove Coin Flips Are Not Random?
Engineering Technology: Statics & Dynamics
Flipping a coin is accepted as an unbiased method to produce a random 50:50 outcome, but kinematics suggest a coin flip should be deterministic, and therefore predictable. I tested whether I…
ISEF · 2022
Conscious Brain Mind-Controlled Cybonthitic Cyborg Bionic-Leg - V2
Biomedical Engineering
Lower limb amputations affect about 28.9 million people worldwide, influencing normal human functions, we are developing a conscious brain mind-controlled Cybonthitic cyborg bionic-leg to pr…
ISEF · 2022
Constructing a Neural Network To Classify Lung Cancer
Robotics and Intelligent Machines
Lung cancer is the leading cause of cancer death, accounting for nearly 25% of all cancer-related deaths. Lung cancer kills more people annually than colon, prostate, and breast cancer combi…