Browse real student projects, abstracts, and awards.
ISEF · 2026
Biomedical Engineering
“Over 105,000 persons in the U.S. died from drug-involved overdose in 2023,” (Ahmad 2024). By creating a device that can detect an overdose and neutralize the effects, hundreds of lives coul…
ISEF · 2026
Biomedical Engineering
Assistive mobility devices are important for improving balance, stability, and independence in individuals undergoing motor rehabilitation. In Puerto Rico, many people experience difficulty…
ISEF · 2026
Biomedical Engineering
Sleep quality is fundamental to overall health, yet many existing sleep-monitoring devices suffer from signal distortion due to poor and inconsistent skin contact during overnight movement.…
ISEF · 2026
Robotics and Intelligent Machines
Nutritious mushrooms can be grown in an efficient and accessible manner by engineering and automating their ideal growing environment. Mushrooms can be a healthy and reliable food source, wh…
ISEF · 2026
Biochemistry
Breast cancer, the most common cancer in US women, accounts for approximately 32% of new diagnoses annually. Approximately 42,170 women will die from breast cancer in 2025. Current treatment…
ISEF · 2026
Cellular and Molecular Biology
Solid tumors contain a tumor microenvironment (TME) with high levels of immunosuppressive metabolites that interfere with T cell activation. While CAR T cells are effective in blood cancers,…
ISEF · 2026
Cellular and Molecular Biology
Cancer immunotherapy seeks to harness the immune system to selectively target tumor cells. This study investigated whether human T cells could be engineered to recognize melanoma cells expre…
ISEF · 2026
Biomedical Engineering
mNeon Green is a fluorescent protein that originates from Branchiostoma lanceolatum . The prior studies on mNeon are minimal, however, there are several studies indicating that fluorescent p…
ISEF · 2026
Environmental Engineering
Wildfire suppression agents commonly rely on synthetic surfactants that pose environmental persistence and runoff concerns, particularly in island ecosystems. This study evaluates the feasib…
ISEF · 2026
Biomedical Engineering
Electrocardiography (ECG) is the primary diagnostic method for cardiovascular disease, the leading cause of mortality. Conventional wet ECG electrodes (Ag/AgCl) are metal-based and rely on c…
ISEF · 2026
Materials Science
Titanium alloys are widely used in biomedical implants due to their high strength-to-weight ratio, corrosion resistance, and biocompatibility. However, the standard Ti–6Al–4V alloy contains…
ISEF · 2026
Plant Sciences
Global food demand requires sustainable strategies to enhance cereal productivity beyond conventional agricultural inputs. The apocarotenoids beta-Cyclocitral (beta-CC) and 3-OH-beta-Cycloci…
ISEF · 2026
Materials Science
The production of Portland cement accounts for approximately 7–8% of global CO2 emissions due to energy-intensive calcination processes, underscoring the urgent need for sustainable alternat…
ISEF · 2026
Materials Science
Button Battery Ingestion (BBI) constitutes a global emergency, reporting over 300,000 cases annually, primarily affecting children under six due to natural exploration, resulting in hundreds…
ISEF · 2026
Microbiology
Type 2 diabetes is associated with chronic inflammation and poor blood glucose control. Some gut bacteria produce butyrate, a short-chain fatty acid that may support gut health and metabolis…
ISEF · 2026
Animal Sciences
The purpose of this research was to evaluate whether adding an Insecta-based protein source to a Gallus gallus domesticus diet would improve overall productivity and egg production rates. In…
ISEF · 2026
Computational Biology and Bioinformatics
The clinical translation of CRISPR-Cas9 therapeutics is limited by the risk of unintended "off-target" mutations, which can cause errors like oncogenic chromosomal alterations. Current compu…
ISEF · 2026
Energy: Sustainable Materials and Design
Global fossil fuel combustion emits 40 billion metric tons of CO2 annually, driving climate change and energy insecurity. Renewable-powered water electrolysis offers a sustainable pathway to…
ISEF · 2026
Software Design
Communication barriers in healthcare settings remain a significant challenge for Deaf and Hard-of-Hearing (DHH) individuals, particularly during patient-provider interactions. This can lead…
ISEF · 2026
Computational Biology and Bioinformatics
Lung cancer is the leading cause of cancer-related mortality worldwide, largely due to diagnosis at advanced stages when treatment is limited. Although low-dose computed tomography (LDCT) sc…
ISEF · 2026
Computational Biology and Bioinformatics
Genetic neurodegenerative diseases affect more than 57 million people worldwide. With aging populations, their prevalence is rising, making early prediction critical for enabling timely inte…
ISEF · 2026
Translational Medical Science
Prior research has indicated that the synthetic peptide D-(KLAKLAK)2 and its analogues exhibit potent cancer toxicity (oncotoxicity) and pro-apoptotic activity when internalized within mamma…
ISEF · 2026
Microbiology
Emerging infectious diseases require accurate spatial risk assessments, yet current strategies in disease ecology lack a clear and reliable framework when direct disease data is lacking. One…
ISEF · 2026
Software Design
The purpose of this project was to design and test a true random number generator using physical noise from an analog input. Most random number generators in common use rely on software algo…
ISEF · 2026
Chemistry
Metals tarnish due to oxidation reactions with their environment. While oxidation leads to corrosion, we don't fully understand how different metals corrode under the same conditions. This e…
ISEF · 2026
Chemistry
The traffic light reaction is a visual chemistry magic experiment that allows the observation of redox reactions. This reaction involves the blue dye indigo carmine (IC) being reduced by glu…
ISEF · 2026
Biochemistry
Alzheimer’s Disease is a neurodegenerative disorder characterized by the hyperphosphorylation of Tau and collapsin response mediator protein-2 (CRMP2), a newly identified and understudied bi…
ISEF · 2026
Environmental Engineering
Equabin is an intelligent IoT based waste management system. The system is built around a micro-controller integrated with multiple sensors, standard communication protocols, and a database.…
ISEF · 2026
Physics and Astronomy
This study examines the dynamics of a spinning pencil cap on a smooth surface—a motion commonly observed during childhood play. As the cap spins about its axis, it simultaneously traces a ci…
ISEF · 2026
Biochemistry
Liver fibrosis is a global health crisis, affecting approximately 7.3% of adults worldwide. The disease is progressive, with advanced stages characterized by formation of a permanent extrace…