20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2023
Biochemistry
Tau protein is an intrinsically disordered protein (IDP) with essential roles in the assembly, stabilization, and modulation of microtubules, which play a critical role in the proper functio…
ISEF · 2023
Biomedical and Health Sciences
Alzheimer’s disease (AD) is the most common neurodegenerative disease and affects memory and learning. Recent data suggest mitochondrial fragmentation in AD likely underlies impaired mitocho…
ISEF · 2023
Robotics and Intelligent Machines
Accidents involving visually impaired people while walking are one of the serious social issues (e.g., falling off station platforms and crossing crosswalks without acoustic signals). The ri…
ISEF · 2023
Translational Medical Science
Cancer accounts for nearly 10 million deaths annually, and treatment relies on identifying tissue origin. Traditional diagnostics are time-consuming, with wait times up to 120 days from symp…
ISEF · 2023
Computational Biology and Bioinformatics First Award
Replication errors represent two-thirds of cancer mutations. A novel subset, micro-changing short tandem repeats (mcSTRs), lack systematic examination in cancers due to complex chromosomal a…
ISEF · 2023
Embedded Systems
The project aims to develop a portable micro-controlled device that uses the Gauss method to calculate irregular areas. The main purpose is being able to help in civil projects with support…
ISEF · 2023
Earth and Environmental Sciences Third Award
Previous research suggests that abiotic factors facilitate the degradation of artificial polymers, such as polyethylene, into microplastics. However, current research has not yet explored ho…
ISEF · 2023
Embedded Systems Fourth Award
In biotechnology, fluorescence is a commonly used optical reporter for signaling the presence of specific substances. However, the use of fluorescence is limited by the high cost of traditio…
ISEF · 2023
Computational Biology and Bioinformatics
The malaria parasite, Plasmodium, infects over 200 million people annually and causes over 500,000 deaths, primarily impacting developing countries. After a decline within the last decade, m…
ISEF · 2023
Earth and Environmental Sciences Second Award
Cyanobacteria blooms in rivers have grown in intensity due to climate change and water pollution. During these blooms, microcystis, a type of cyanobacteria, releases toxins called microcysti…
ISEF · 2023
Physics and Astronomy Fourth Award
Observations and theoretical simulations suggest that the large scale environment plays a significant role in how galaxies form and evolve and, in particular, whether and when galaxies host…
ISEF · 2023
Biomedical Engineering Third Award
3D pose estimation, the task of reconstructing the skeletal structure of a human subject, has a plethora of applications in medicine, the animation industry, augmented reality, and much more…
ISEF · 2023
Animal Sciences
Cancer radiotherapy weakens surrounding benign cells whilst eradicating a malignant tumor. These consequences are indicative of a general decline in cellular vitality within the organism. Em…
ISEF · 2023
Plant Sciences Third Award
The purpose of this experiment is to evaluate two transgenic and one exogenous approach to ameliorating decreased protein synthesis under elevated carbon dioxide (CO2) in A. thaliana, as wel…
ISEF · 2023
Cellular and Molecular Biology
Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD) are all classified as neurodegenerative disorders. In many neurodegenerative diseases, TDP-43…
ISEF · 2023
Behavioral and Social Sciences Third Award
With the increasing use of social media in our daily lives, it is crucial to maintain safe and inclusive platforms for users of diverse backgrounds. Offensive content can inflict emotional d…
ISEF · 2023
Engineering Technology: Statics & Dynamics
This project seeks to improve the overall sustainability of the bicycle industry by improving helmet materials and design. To accomplish this, I made use of 3D modeling and printing in combi…
ISEF · 2023
Engineering Technology: Statics & Dynamics
The frequency of rocket launches has greatly intensified in the recent decade. Reusability is sought after in an effort to reduce the cost of launches and give rise to a new era of space exp…
ISEF · 2023
Behavioral and Social Sciences
In the last decade, there was a significant increase in interest in mental health services, particularly in young adult populations, which has resulted in university counseling departments b…
ISEF · 2023
Physics and Astronomy
Most of the Milky Way’s stellar mass has been observed to be located in the inner parts of the galaxy which, for larger radii, should give a rotational velocity inversely proportional to the…
ISEF · 2023
Robotics and Intelligent Machines
Functional brain networks represent dynamic connectivity patterns among brain regions that change across cognitive states and in response to disease or injury. Graph-based models are a relat…
ISEF · 2023
Biomedical and Health Sciences
Diabetes, characterized by hyperglycemia, affects human fertility. The animal model Caenorhabditis elegans is used to research human diseases due to its molecular-level similarities and ethi…
ISEF · 2023
Plant Sciences
Climate change is wrecking the agricultural sector, with summer water availability decreasing while water needs are increasing worldwide. UC Merced estimates that over $3 billion in agricult…
ISEF · 2023
Computational Biology and Bioinformatics
The rapid mutation of COVID-19 has made the pandemic prolonged, requiring flexible implementation of virus mutation, immunity, and anti-pandemic policies. However, traditional mathematical a…
ISEF · 2023
Translational Medical Science First Award
Three million people in the U.S. suffer from gluten intolerance/celiac disease (CD). In these patients, the digestive system cannot digest gluten proteins. My project aims to solve this issu…
ISEF · 2023
Engineering Technology: Statics & Dynamics Fourth Award
Squirrel cage induction motors are the most widely used electric motor design, especially for industrial purposes such as AC compressors and fans. However, they lack the high starting torque…
ISEF · 2023
Chemistry Fourth Award
Acetaminophen is a molecule commonly taken medicinally, yet also can present dangers due to overdosage and environmental contamination. To address these concerns, accurate detection of aceta…
ISEF · 2023
Cellular and Molecular Biology
Cellular mechanosensation is an important biological function that enables cells to sense the mechanical cues of its extracellular environment and to change phenotypes and cell lineage accor…
ISEF · 2023
Biomedical Engineering
Temporomandibular joint disorders (TMDs) are a common and significant health issue affecting about 5-12% of the US population. While clinical data has indicated strong associations between t…
ISEF · 2023
Biochemistry
Opioids are leading contributors to drug overdose deaths. Currently, there are no pain medications without risk of misuse, abuse, and addiction. Oxytocin, a pituitary hormone, holds analgesi…