20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2023
Computational Biology and Bioinformatics Fourth Award
A key drawback of traditional chemotherapy drugs like cisplatin is that they target both healthy and cancerous cells and are highly toxic in high or medium doses. The Warburg Effect states t…
ISEF · 2023
Translational Medical Science
In multiple sclerosis (MS), existing diagnostic tools, including clinical magnetic resonance imaging (MRI) and neurological status scales, do not reliably represent disease severity or progr…
ISEF · 2023
Biochemistry
Although cataract is the leading cause of blindness, there remains no treatment besides surgical removal. Identification of specific differences between normal and cataract lenses is essenti…
ISEF · 2023
Energy: Sustainable Materials and Design
This project aims to find natural solutions to reduce carbon dioxide contributing to climate change while expanding access to lighting. There Species of marine dinoflagellates, such as Pyroc…
ISEF · 2023
Biomedical and Health Sciences
Recent research on the drug famotidine suggests it may be an affordable, accessible, safe, and effective treatment against COVID-19. Famotidine is a histamine 2 receptor (H2R) antagonist tha…
ISEF · 2023
Chemistry Fourth Award
Annually, 60,000 tons of textile wastewater are discharged into waterways. Azo dyes constitute a major proportion, polluting waterways by inhibiting light penetration; impairing marine organ…
ISEF · 2023
Physics and Astronomy
This experiment investigated the characteristics of the decoherence of qubits in quantum computers and the effects of decoherence on the superimposed state of the qubit. Four different tests…
ISEF · 2023
Translational Medical Science
This study aimed to determine whether traumatic brain injury (TBI) causes learning and short-term memory (STM) deficits in Drosophila melanogaster, and if THIP, a GABA-A receptor agonist, wi…
ISEF · 2023
Animal Sciences
Turmeric (Curcuma longa) and poppy seeds (Papaver somniferum) are two substances that are widely used in the cuisines of many South Asian and Middle Eastern countries. These compounds have a…
ISEF · 2023
Translational Medical Science
Vinblastine is a cytotoxic drug that has been proven to stunt the growth of cancer cells by binding to the mitotic spindle during anaphase. Studies have shown that Alpha Tocopheryl, a type o…
ISEF · 2023
Energy: Sustainable Materials and Design
Greenhouse gases are causing mass climate change, and one of the largest emitters of greenhouse gasses is electricity powered by fossil fuels. Solar panels help reduce our dependence on this…
ISEF · 2023
Biomedical and Health Sciences
Although stem cell transplants have made promising clinical progress as a treatment for leukemia and other blood cancers, their safety and the severe complications they pose have significant…
ISEF · 2023
Biomedical and Health Sciences
Myocardial infarction (MI), or heart attack, is the death of cardiac tissue to improper blood and oxygen flow. MI is a form of cardiovascular disease, the current leading cause of death, acc…
ISEF · 2023
Animal Sciences
Visual impairment is linked to increased all-cause mortality and elevated risk of ischemic heart disease, but its causal relationship is unclear. This study investigated whether visual impai…
ISEF · 2023
Physics and Astronomy
The M-Sigma relation is a well-known empirical correlation discovered between black holes and their host galaxies relating the mass of a black hole to its surrounding bulge. The conventional…
ISEF · 2023
Physics and Astronomy
Hot Neptunes are extrasolar planets that are similar in size to Neptune in our solar system but are much closer to their host stars, completing an orbit in 10 days or less. The origin of hot…
ISEF · 2023
Biomedical and Health Sciences Fourth Award
Type two Diabetes is an epidemic. Because there is no cure for diabetes and the current treatments can be expensive and inaccessible, exploration for more affordable management tools for the…
ISEF · 2023
Physics and Astronomy
The question of whether or not plants exploit quantum coherent effects in order to transport energy through their photosynthetic antenna is currently very controversial in the biophysics com…
ISEF · 2023
Translational Medical Science Fourth Award
G-quadruplex structures (G4s) are one of many secondary structures that genomic DNA adopts, apart from its canonical B-form, and they are a vital part of cellular regulation. Sequences that…
ISEF · 2023
Translational Medical Science Third Award
Small cell lung cancer (SCLC) is an extremely aggressive form of lung cancer with a less than 5% five-year survival rate. The poor prognosis is mainly attributed to the lack of effective, lo…
ISEF · 2023
Computational Biology and Bioinformatics
Rare, aggressive pediatric brain tumor ETMR is frequently misdiagnosed, reducing chances of survival. Early diagnosis is crucial due to its short average 12 month prognosis. While ETMR is ch…
ISEF · 2023
Energy: Sustainable Materials and Design
The use of biofuels such as cellulosic ethanol has the potential to decrease the amount of carbon emissions. Algae is a potential source of biomass to produce such cellulosic ethanol, but th…
ISEF · 2023
Cellular and Molecular Biology
The proper formation of a zygote requires extensive epigenetic reprogramming to enable appropriate inheritance of histone methylation. In C. elegans, this reprogramming is mediated by the H3…
ISEF · 2023
Earth and Environmental Sciences
Starting with reports of illness after swimming in the lake in 2022, the Fallon County Commission decided to test the lake for toxic algae. The lake tests came back positive for a toxic alga…
ISEF · 2023
Biochemistry
Metallomic imbalance impacts tumor malignancy. Previous work developed by Stelling, and collaborators demonstrated that manganese is accumulated in tumors in vivo and that tumor cells in vit…
ISEF · 2023
Translational Medical Science
Ginkgo biloba is an essential herbal agent that is effective on nerve cells and may have therapeutic or preventive effects with its water-soluble bioactive components. In our study, we worke…
ISEF · 2023
Environmental Engineering
The Earth's atmosphere is essential to sustaining life and preserving the current global climate. However, the industrial revolution has resulted in high pollution levels that have altered t…
ISEF · 2023
Earth and Environmental Sciences
Current research shows Northern Guam to be composed of porous limestone bedrock which allow groundwater to flow out. One large discharge point has already been identified last year in north-…
ISEF · 2023
Cellular and Molecular Biology
Although UC-MSCs are preferred for clinical administration, they are retrieved in minute amounts. The scale-up requirement for human consumption is 1 million cells/kg of body weight. This de…
ISEF · 2023
Environmental Engineering
The project aims to implement a dynamic solid waste collection system that relies on level sensors installed in dustbins. The sensors will monitor the levels of waste in the bins, and the da…