Browse real student projects, abstracts, and awards.
ISEF · 2026
Robotics and Intelligent Machines
Autonomous drone fleets have immense potential in medical supply delivery during disaster incident response. However, coordinating multiple drones in such settings introduces compounding cha…
ISEF · 2026
Biochemistry
Cancer remains a leading cause of death worldwide, accounting for approximately 10 million deaths annually, and is strongly associated with genome instability and replication stress. Aphidic…
ISEF · 2026
Embedded Systems
Cryogenic Electron Microscopy (Cryo-EM) is the cornerstone technique for determining atomic-resolution structures of proteins implicated in neurodegenerative diseases like Alzheimer’s. Howev…
ISEF · 2026
Environmental Engineering
Roughly 46 million tons of mixed-fabric waste and 5 billion tons of Styrofoam waste end up in landfills each year. These industries alone account for around 35.5% of all landfill waste. Mixe…
ISEF · 2026
Behavioral and Social Sciences
Disease-spread and its consequences are governed by a multitude of factors, but only recently has culture been considered among its predictors. The individualism-collectivism spectrum, which…
ISEF · 2026
Physics and Astronomy
Dark matter constitutes approximately 85% of the matter in the universe and is inferred through gravitational lensing, in which both baryonic and dark matter bend light from distant galaxies…
ISEF · 2026
Microbiology
Drug-resistant Candida albicans infections are rapidly outpacing current antifungal therapies as mutations in the ERG11 enzyme reduce azole drug efficacy and drive treatment failure. Most an…
ISEF · 2026
Physics and Astronomy
Dark matter is the primary component of galaxy clusters and a driver of cosmic structure formation, yet its impact on cluster properties remains poorly understood. While the Navarro-Frenk-Wh…
ISEF · 2026
Biomedical and Health Sciences
COVID-19 infection causes disordered sugar metabolism, both in acute infection and long COVID. Diabetic COVID-19 patients with hyperglycemia have higher mortality rates, and infection elevat…
ISEF · 2026
Behavioral and Social Sciences
Indian educational reforms under the 2020 National Education Policy (NEP) aim to shift from rote memorisation toward creative thinking, a move that, alongside rising AI automation, demands s…
ISEF · 2026
Computational Biology and Bioinformatics
PFAS (per- and polyfluoroalkyl substances) are organohalogens that are dubbed “forever chemicals” because they can remain in the environment for over 1,000 years. Chlorination-derived disinf…
ISEF · 2026
Translational Medical Science
GLP-1 receptor agonists are widely used to treat diabetes and obesity and are being investigated for potential cognitive benefits in Alzheimer's disease. However, these treatments simultaneo…
ISEF · 2026
Robotics and Intelligent Machines
Hyperspectral imaging enables simultaneous acquisition of spatial and spectral information and has become indispensable in applications including material characterization, environmental eng…
ISEF · 2026
Biochemistry
Polyethylene terephthalate (PET) represents one of the most prominent forms of synthetic plastic pollution, accounting for over 50 million tons of annual waste worldwide. Although the discov…
ISEF · 2026
Physics and Astronomy
Solar flares are a major component of understanding solar weather. Geomagnetic storms resulting from solar flares can cause catastrophic damage to man-made satellites in space, disruption to…
ISEF · 2026
Computational Biology and Bioinformatics
This project’s purpose was to find alternatives to the PET-plastic degrading enzyme ‘PETase’ from vast amounts of existing protein data that function at industrial temperatures (~70°C) for a…
ISEF · 2026
Biomedical and Health Sciences
Each year, about 58,500 Americans are diagnosed with oral or oropharyngeal cancer, and over 12,000 of them will not survive it. When oral cancer is caught at a localized stage, the 5-year su…
ISEF · 2026
Software Design
Deepfake videos are increasingly convincing, yet current detectors show a frustrating gap between lab performance (over 90% accuracy) and real-world results (50–60% AUC) with latencies too s…
ISEF · 2026
Materials Science
Medication is one of the most significant inventions in human history, often serving as a lifesaving intervention. However, access to medicine remains a major challenge due to high costs, es…
ISEF · 2026
Chemistry
The production of formic acid through the electrochemical reduction of carbon dioxide has garnered significant attention as both a valuable chemical production pathway and a carbon reduction…
ISEF · 2026
Plant Sciences
Global agricultural sustainability is currently threatened by the inefficient use of chemical fertilizers, which often leach into ecosystems as pollutants rather than being absorbed by crops…
ISEF · 2026
Physics and Astronomy
This project modeled the effects of Hawking radiation on black hole evolution and investigated whether black hole initial conditions can be inferred from radiation temperature data. A numeri…
ISEF · 2026
Computational Biology and Bioinformatics
The rapid evolution of pathogens such as SARS-CoV-2 and influenza has consistently outpaced traditional monoclonal antibody discovery. Frequent mutations in key antigenic regions enable immu…
ISEF · 2026
Computational Biology and Bioinformatics
Medical AI systems fail on underrepresented populations in ways conventional fairness metrics cannot detect. Existing evaluations report average disparities at fixed thresholds, providing no…
ISEF · 2026
Engineering Technology: Statics & Dynamics
This study investigates the development of a more efficient transmission and generator system for wind turbines. Current mechanical transmissions in turbines suffer energy losses from fricti…
ISEF · 2026
Physics and Astronomy
This study proposes an improved compact Cassegrain-based imaging system for ultra-telephoto applications. To reduce the trade-off among focal length, structural length, and central obscurati…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Approximately 50% of dogs suffer from anxiety caused by high-intensity sounds (Grigg., et al., 2021). This is why this project worked on the design and construction of a treat dispensing mac…
ISEF · 2026
Robotics and Intelligent Machines
My science fair project works towards creating a hardware and software platform for automated AI-assisted fire suppression. Through a combination of an AI model, self-generated training data…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Currently aviation produces considerable carbon emissions and high operating costs, making sustainable flight a key focus. Electric aircraft are widely viewed as an alternative due to their…
ISEF · 2026
Biomedical Engineering
Developing functional prostheses for the upper limb, has historically been a challenge. Amputation of the hand due to military injury, disease, or other trauma carries significant psychosoci…