Browse real student projects, abstracts, and awards.
ISEF · 2024
Behavioral and Social Sciences Fourth Award
Previous research suggests people exhibit an "empathy gap": they feel more empathy for members of their group than for outsiders. I explored whether the empathy gap exists in racial and part…
ISEF · 2024
Cellular and Molecular Biology
Lysophosphatidic acid (LPA) is a bioactive lipid which can bind to six LPA receptors (LPA1-6) on the cell membrane and regulate various cell activities. Previous studies have shown that LPA1…
ISEF · 2024
Technology Enhances the Arts First Award
As digital design has become ubiquitous over the last few decades, 3D creations have become much more advanced through Computer-Aided Design (CAD). However, this approach can be tedious, tim…
ISEF · 2024
Biomedical and Health Sciences
Triple-negative breast cancer (TNBC) is a molecular subset of breast cancer defined by a lack of estrogen, progesterone, and the human epidermal growth factor 2 (HER2) receptors. Currently,…
ISEF · 2024
Physics and Astronomy Second Award
The discovery of M51-ULS-1b, the only extragalactic planet orbiting an X-ray Source (XRS), unveiled a gap in our current understanding of planetary formation and evolution. How this planet f…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
UGT1A1 is an enzyme involved in metabolizing Irinotecan, a DNA topoisomerase class I inhibitor chemotherapeutic drug. Polymorphisms within the UGT1A1 promoter reduce UGT1A1 mRNA expression,…
ISEF · 2024
Physics and Astronomy Third Award
Since 2010, astronomers have utilized automated algorithms to detect numerous exoplanets that primarily exhibit Medium to High Signal-to-Noise Ratio (SNR) transits. About 60% of potential ha…
ISEF · 2024
Translational Medical Science
Commonly known as the yellow water lily root or kaandoosh in Ojibwe language, the rhizome of Nuphar advena is utilized by Indigenous communities for treating bacterial overgrowth. This study…
ISEF · 2024
Cellular and Molecular Biology
Hypoxia Inducible Factor 1 Alpha (Hif1a) contributes to cancer growth in most solid tumors. Because normal cells do not generally require HIF1, it is a potential target. How cancer will adap…
ISEF · 2024
Cellular and Molecular Biology
Natural Killer (NK) cells are an essential component of innate host defense against Hepatocellular Carcinoma (HCC). A central determinant of NK cell function is their tissue residency. I hyp…
ISEF · 2024
Animal Sciences
Artificial insemination relies on viable semen, the maintenance of which in the swine industry is a challenge due to the gradual decline in sperm quality during chilled storage. Previous stu…
ISEF · 2024
Materials Science
Nanomedicine is a rapidly growing field, however limited understanding of molecular mechanisms hinders the development of next generation gene-targeting drugs. Ethidium bromide (EB) is a com…
ISEF · 2024
Cellular and Molecular Biology
In living organisms, DNA is a critical macromolecule; its stability and integrity are vital for the normal functioning of cellular processes, such as DNA replication and DNA repair. Sunlight…
ISEF · 2024
Chemistry
Hydroponics, in which the plant environment is controlled and managed, has been found to be effective in increasing food production. This is extremely important to meet the needs of future p…
ISEF · 2024
Animal Sciences
Canine mammary tumors (CMTs) represent the most common neoplasia in female dogs. Histopathology analysis is considered the gold standard for classification but is invasive and does not alway…
ISEF · 2024
Embedded Systems Fourth Award
Over the past two decades, educational institutions have witnessed an exponential increase in school shootings and gun-related threats, marking a prominent need for enhanced security solutio…
ISEF · 2024
Chemistry
I developed a novel photochromic system using methylene blue with ascorbic acid and investigated the optimal photochromic conditions. The photochromic solution is environmentally friendly an…
ISEF · 2024
Engineering Technology: Statics & Dynamics
Black ice, a thin coating of ice on the road surface, is the leading cause of traffic accidents. According to the U.S. Department of Transportation, black ice accounted for 3.6 times more ca…
ISEF · 2024
Chemistry
Approximately 37.3 million Americans suffer from Type Two Diabetes Mellitus (T2DM), a disorder in which the body fails to regulate sugar levels. In T2DM, insulin resistance reduces the avail…
ISEF · 2024
Technology Enhances the Arts
Helen Keller was a remarkable woman who achieved success and fame despite losing her sight and hearing. The deafblind range is 0.2% to 2%, which represents 467 million of the global populati…
ISEF · 2024
Physics and Astronomy
Solar energy is one of the most prominent sustainable sources of global energy while also powering space exploration. However, the efficiency of solar panels is undermined by the accumulatio…
ISEF · 2024
Cellular and Molecular Biology
Yes-associated protein 1 (YAP1) is a transcriptional coactivator known for driving oncogenesis. YAP1 is able to revive the gene expression of transcription factor FOS following the downregul…
ISEF · 2024
Chemistry
Brazil is a world leader in coffee production and is the second-largest consumer. As a result, over 1,000,000 t of coffee grounds accumulate in landfills yearly and decompose, releasing gree…
ISEF · 2024
Energy: Sustainable Materials and Design
Climate change continues to worsen through greenhouse gasses as up to 40 billion tons of gasses will be in the atmosphere by the end of 2023. With a fourth of those emissions coming from gas…
ISEF · 2024
Systems Software Third Award
Machine Learning (ML) optimizers are widely used to optimize the weights and biases of deep neural networks. However, current methods can suffer from issues like slow convergence and getting…
ISEF · 2024
Biomedical and Health Sciences
Ankylosing Spondylitis a type of rheumatic autoimmune disorders where normal body cells attack musculoskeletal cells, making bones' weak joints unstable and prone to fractures. This can caus…
ISEF · 2024
Robotics and Intelligent Machines Second Award
Every year, six million people die from cardiac arrest in the world with 436,000 victims in the United States alone. This problem is made worse because, in many counties, more than 50% of pe…
ISEF · 2024
Biomedical and Health Sciences
Colorectal Cancer (CRC) is the second leading cause of cancer death. This is because during early stages, CRC is difficult to catch, which means that treatment can only be offered after the…
ISEF · 2024
Environmental Engineering
The production of nitrogen fertilizers has made it possible to grow enough crops to keep up with the growing population. This excessive input of nitrogen fertilizers on crops is causing leac…
ISEF · 2024
Earth and Environmental Sciences Second Award
Oil spills continue to affect millions of families yearly. Significant research has gone into the development of both organic and inorganic solvents. However, the issue with these sorbents i…