Browse real student projects, abstracts, and awards.
ISEF · 2024
Biomedical and Health Sciences
Chimeric Antigen Receptor (CAR) T cells and Bispecific T cell Engagers (BiTEs) are two novel immunotherapy platforms. I hypothesized that the different mechanisms used by anti-CD3-CD19 BiTEs…
ISEF · 2024
Behavioral and Social Sciences
Technology dependency is increasing; estimations say 97% of Americans own a smartphone (Pew Research 2024); therefore, it is important to know how it affects society. This project aimed to d…
ISEF · 2024
Earth and Environmental Sciences Fourth Award
Planetary biodiversity is declining at alarming rates. Species conservation depends on knowing what species are present in an environment and in what quantities. A keystone species in Alaska…
ISEF · 2024
Physics and Astronomy Fourth Award
Gravitational waves are caused by fluctuations in the curvature of spacetime from Einstein's general theory of relativity. When black holes or objects with high mass orbit each other or coll…
ISEF · 2024
Microbiology Fourth Award
Plant-based natural products are utilized as active ingredients in herbal medicines, and studying their bioactivities leads to better understanding of their possible medicinal value. The pre…
ISEF · 2024
Computational Biology and Bioinformatics
Mucin-1 MUC1 is a high molecular weight glycoprotein that can overexpress, causing various cancers and playing a significant role in tumor progression and metastasis. Developing targeted the…
ISEF · 2024
Animal Sciences
Niacin is an essential nutrient for life. It serves as a precursor to nicotinamide adenine dinucleotide (NAD+), a critical coenzyme for ATP production, DNA repair and gene expression. In hum…
ISEF · 2024
Biomedical Engineering
According to the WHO, respiratory diseases are among the leading causes of mortality, and collectively, over one billion people suffer from acute or chronic respiratory conditions worldwide.…
ISEF · 2024
Embedded Systems Third Award
Importance: Decompensated heart failure causes 3 million rehospitalizations. This is a result of current ineffective and inaccessible cardiac monitoring standards, which rely on symptoms tha…
ISEF · 2024
Robotics and Intelligent Machines
This paper presents an approach to utilizing Large Language Models (LLMs) for the control and coordination of robotic swarms. It explores how LLMs can improve the efficiency of swarm robotic…
ISEF · 2024
Technology Enhances the Arts
Humanity has made great strides in Artificial Intelligence (AI) development since the 1960s. Today, because such technology has been made available to the public, there has been a rise in AI…
ISEF · 2024
Energy: Sustainable Materials and Design Third Award
In response to immense international energy demands, the industrial sector must witness a historic alteration for bulk energy storage with a wide range of up-scaling spectra for commercial u…
ISEF · 2024
Biomedical Engineering
Thoracentesis is a surgical procedure where a needle is inserted into the pleural cavity around the lungs to extract pleural fluid. Measuring the pleural pressure during thoracentesis is a g…
ISEF · 2024
Mathematics
For a fixed positive integer b?N, let the b-sight lines be defined by f(x)=ax^b, for a?Q, with the origin O as the observing point (the position of the eyes). A point in the square lattice V…
ISEF · 2024
Environmental Engineering Third Award
Both the disposal of rejected brine and CO2 emission are the most significant challenges associated with the desalination process. Herein, we present an integrated approach that utilizes a r…
ISEF · 2024
Technology Enhances the Arts Third Award
Classical music education is a complex field requiring the teacher to evaluate a student based on audio and visual information. However, this approach can be error prone and biased. This pro…
ISEF · 2024
Robotics and Intelligent Machines
Controlling a prosthetic hand is cognitively demanding and up to 44% of upper-limb amputees abandon their prosthesis. There is a need for prosthetic control strategies that are more intuitiv…
ISEF · 2024
Translational Medical Science
Duchenne Muscular Dystrophy (DMD) is an inherited X-linked disease with an incidence of 1:3,600. Patients become weak at 2-3 years old with progression to a wheelchair in their early teens,…
ISEF · 2024
Biomedical and Health Sciences
Glioblastoma Multiforme (GBM) is an aggressive and fast-growing form of brain cancer with a high rate of mortality. It is the most common malignant brain tumor in adults, accounting for 47.7…
ISEF · 2024
Engineering Technology: Statics & Dynamics Third Award
Pipeline is a typical complex environment, and pipeline robots greatly improve work efficiency. However, the existing robots have limited forms, and lack of passibility and flexibility. So t…
ISEF · 2024
Systems Software
Crowd crushes are a widespread global issue often resulting in significant loss of life. Proactively addressing this challenge involves avoiding locations predicted to attract large crowds.…
ISEF · 2024
Mathematics
Over the course of history, different ways of hiding messages have been created, and this investigation was done to achieve that using RSA and dates. The way that this encryption system work…
ISEF · 2024
Mathematics
Studying population dynamics is key to protecting vital aquatic ecosystems and the economic activities they support, such as those of the Chesapeake Bay. Mathematics is a powerful tool that…
ISEF · 2024
Physics and Astronomy
The effects of spacetime curvature, described in General Relativity, are made visible to us through gravitational lensing phenomena. Microlensing events (ML events) represent a type of gravi…
ISEF · 2024
Biomedical and Health Sciences
Systemic sclerosis (SSc) is an autoimmune disease with multiple organ involvement, including lung, skin, gastrointestinal tract, and kidneys. A subset of SSc patients develops a critical ren…
ISEF · 2024
Biomedical and Health Sciences
Facioscapulohumeral muscular dystrophy (FSHD) is a genetic, progressive myopathy and the second most common muscular dystrophy. Progression of the disease primarily begins in the facial, sho…
ISEF · 2024
Cellular and Molecular Biology First Award
In a recent study, 33% of individuals with neurodevelopmental disorders (NDDs) carried mutations in ASXL3, whose function is unknown. To understand ASXL3’s role in NDDs, we used CRISPR techn…
ISEF · 2024
Plant Sciences
Rice (Oryza sativa L.) is a staple food, providing 20% of the caloric needs for half of the global population. Rice production is adversely affected by abiotic stresses such as drought, sali…
ISEF · 2024
Biomedical Engineering
Functional Magnetic Resonance Imaging (fMRI) is pivotal in understanding brain activity, but its efficacy is often hampered by slice-timing correction artifacts known as 'zebra-artifacts'. T…
ISEF · 2024
Robotics and Intelligent Machines
Brain-computer interface (BCI) enables direct communication between the brain and external devices, with applications ranging from the rehabilitation of motor disabilities to enhance human-c…