Browse real student projects, abstracts, and awards.
ISEF · 2024
Physics and Astronomy Fourth Award
In 2022, the Satellite Industry Association reported a staggering 45% increase in the number of operational satellites, resulting in an orbital population exceeding 7,000 around Earth. With…
ISEF · 2024
Biomedical Engineering Fourth Award
Annually, brain tumors affect 90,000 people nationwide, and have 5-year survival rates as low as 5%. Surgery, the most popular treatment, hinges on accurate pre-operative planning & detectio…
ISEF · 2024
Biomedical Engineering
Many intracranial aneurysms can be treated using flow diversion, in which a finely meshed stent is used to reduce blood flow into an aneurysm. Over time, this leads to endothelial tissue reg…
ISEF · 2024
Animal Sciences Fourth Award
Organisms detect sensory stimuli through peripheral neurons and transmit the information to cortical brain regions for processing: creating an internal neural map of the external environment…
ISEF · 2024
Cellular and Molecular Biology Third Award
Peripheral T-cell lymphoma (PTCL) is a rare and aggressive non-Hodgkin lymphoma resulting from clonal proliferation of mature post-thymic T-cells. The mechanisms behind PTCL development and…
ISEF · 2024
Biochemistry Fourth Award
Antimicrobial resistance(AMR) is a global health threat and the discovery of new antimicrobial compounds has been limited in the past four decades. New antimicrobials with new functions are…
ISEF · 2024
Biomedical and Health Sciences
Introduction While the incidence of esophageal adenocarcinoma is rapidly increasing, the prognosis remains poor with a five-year survival rate of 20%. Therefore, the discovery of new molecul…
ISEF · 2024
Physics and Astronomy Second Award
Every second in the universe an exciting event is occurring, whether it be the collision of two black holes or the death of a star in an explosive supernova. One such event is a Tidal Disrup…
ISEF · 2024
Chemistry
My Zuni ancestors lived in the Grand Canyon long ago. A Zuni medicine man pointed out many Zuni features to my mentor on a Grand Canyon Rafting Tour, sponsored by the Grand Canyon Conservanc…
ISEF · 2024
Chemistry Third Award
Each week, over 60 million individuals consume acetaminophen in the U.S. alone. Despite global reliance for its analgesic & antipyretic (pain & fever relief) properties in medications, aceta…
ISEF · 2024
Energy: Sustainable Materials and Design
The use of smart devices in applications like wildlife tracking and blue energy has become widespread, relying on batteries to power devices in remote locations. However, the frequent mainte…
ISEF · 2024
Energy: Sustainable Materials and Design
The average solar panel is able to convert around 15-20% of solar energy into chemical energy. Therefore, there is a mass amount of energy that has the capability to be captured and harnesse…
ISEF · 2024
Computational Biology and Bioinformatics Second Award
Conventionally, tumorigenesis is understood as a gradual accumulation of genetic mutations. Yet, chromoplexy rearrangements (ChRs) are a mutational phenomenon characterized by highly complex…
ISEF · 2024
Behavioral and Social Sciences
Overexposure to manganese (Mn) through contaminated water or occupational environment has been shown to result in dopaminergic dysfunction and overall neurotoxicity in the human brain [1]. T…
ISEF · 2024
Biomedical and Health Sciences
Chronic kidney disease (CKD) results in a progressive loss of kidney function over time, affecting 37 million in the US. Chymase is the primary enzyme mediating angiotensin II formation inde…
ISEF · 2024
Biomedical and Health Sciences
Over 1 million deaths annually can be attributed to suicide, yet no biomarkers exist. This study investigated blood-brain barrier (BBB) disruption by examining claudin-5 (CLDN5) epigenetic a…
ISEF · 2024
Earth and Environmental Sciences
Increasing pollution in large water bodies poses a significant threat to the availability of safe drinking water. As pollutants (surfactants) decrease interfacial tension, when a contaminant…
ISEF · 2024
Biomedical Engineering Third Award
Hearing loss is the fourth most prevalent disability worldwide, affecting one in five people, and is correlated with depression, isolation, and decreased life expectancy. Innovation in heari…
ISEF · 2024
Translational Medical Science
Traumatic Brain Injury (TBI) is an intracranial damage common among soldiers and impact-sport athletes. In severe cases, TBI is associated with neurodegeneration and dementia if left untreat…
ISEF · 2024
Animal Sciences Third Award
Alzheimer's disease, the most prevalent form of dementia affecting over 24 million people worldwide, is characterized by cognitive decline and progressive neurodegeneration; this is mainly d…
ISEF · 2024
Systems Software
COCOTherm addresses the challenges of monitoring wildlife overpasses as part of the I-90 Snoqualmie Pass East Project. The wildlife monitoring program for this project involves 15 networked…
ISEF · 2024
Systems Software
Coded stock trading strategies are a fast-growing interest as they can help businesses and individuals not only learn but also make more money while putting themselves at less risk. I decide…
ISEF · 2024
Robotics and Intelligent Machines
Riding a bike is a carbon-efficient mode of transportation and a positive way to maintain fitness. However, the inherent difference in speed and size between cars and bikes makes it dangerou…
ISEF · 2024
Materials Science
Food safety is one of the most important components of human life. The World Health Organization estimates that foodborne contamination kills 420,000 people per year worldwide. To combat thi…
ISEF · 2024
Plant Sciences Fourth Award
Huanglongbing (HLB), more commonly known as citrus greening, is a devastating disease caused by bacteria that colonize tree phloem, restrict nutrient flow, and cause symptoms such as fruit d…
ISEF · 2024
Microbiology
Biofilm is the consortia of sessile groups of microbial colonies that adhere on biotic and abiotic surfaces with the help of extracellular polymeric substances (EPS) and glycocalyx. ESKAPE b…
ISEF · 2024
Computational Biology and Bioinformatics
Each year, the escalating drug epidemic causes over 100,000 deaths in the US. 80% of these mortalities result from multiple drug use toxicity, which yields unpredictable and potentially fata…
ISEF · 2024
Systems Software
The rise of community support platforms has captured the attention of various fields, from leisure to customer support. The existing solutions are often exclusive or add-ons to existing syst…
ISEF · 2024
Plant Sciences
This study compares the impact of applying Indigenous Microorganisms (IMOs) cultivated through Natural Farming practices (IMO2-5) and the legume Coastal Jack-bean (Canavalia rosea) with synt…
ISEF · 2024
Energy: Sustainable Materials and Design
Today, the world is transitioning from fossil fuels to renewables, necessitating energy storage due to the intermittent nature of these new sources. To address this issue, we turned to natur…