Browse real student projects, abstracts, and awards.
ISEF · 2019
Animal Sciences
The purpose of this research was to demonstrate the larvicidal properties of Caffeine in inhibiting the growth of Anopheles quadrimaculatus mosquito larvae. An experiment was conducted to in…
ISEF · 2019
Biomedical and Health Sciences
The need for an alternative method of pain control has become critical in the United States due to the opioid epidemic. The CDC has created guidelines with patient risk categories related to…
ISEF · 2019
Animal Sciences
Dendrobates auratus is a species of poison dart frog with skin secretions that contain diet-derived alkaloids. Plant alkaloids have been used in cancer research, so alkaloids in D. auratus s…
ISEF · 2019
Biomedical and Health Sciences Third Award
Cancer has two halves: malignant cells that initiate oncogenesis, and cancer stromal cells that form the tumor microenvironment. Isocitrate dehydrogenases (IDHs) are enzymes in normal cellul…
ISEF · 2019
Translational Medical Science
Rapamycin is an immunosuppressant that inhibits mTOR (the mammalian target of rapamycin) and extends lifespan in organisms such as worms, flies, and mice. While it is known that rapamycin’s…
ISEF · 2019
Cellular and Molecular Biology
The extent of cell to cell communication between macrophages and tumor melanoma cells in mice was investigated. Two experiments were run. The first was an MTT assay which investigated whethe…
ISEF · 2019
Physics and Astronomy
In this project, a procedure for building an x-ray generator was developed and tested. This procedure uses inexpensive or common materials (around $200 total) for the x-ray tube and power so…
ISEF · 2019
Earth and Environmental Sciences
Removing carbon dioxide (CO2) from mixed gas streams is vital for industrial flue gas remediation, fuel gas refining, and chemical production. Existing liquid amine technology is hampered by…
ISEF · 2019
Materials Science
The need for an effective, renewable water filter is greater than ever. One solution to this is novel carbon materials, with a potential source of these materials being cyanobacteria. Cyanob…
ISEF · 2019
Materials Science
Missions to explore the moon and Mars are confronted with great difficulties and challenges, one of these challenges is to reduce and eliminate the harmful impact of the dust on the astronau…
ISEF · 2019
Biomedical and Health Sciences
The purpose of this experiment was to test whether foods rich in High Density Lipoproteins (HDL’s) cholesterol would be successful in treating heart disease. Because heart disease is caused…
ISEF · 2019
Biomedical Engineering
PURPOSE Catheters inserted into the human body are lifesaving. However, microorganisms can attach to their surface and form a biofilm resulting in life threatening infections. There are no p…
ISEF · 2019
Cellular and Molecular Biology Fourth Award
Abscission, the final stage of cytokinesis, is characterized by the separation of cells through the severing of the intercellular bridge at the midbody. Components of the Endosomal Sorting C…
ISEF · 2019
Chemistry
Mosquitoes of the genus Aedes, Culex and Anopheles transmit diseases such as Dengue, West Nile Virus and Malaria, killing more than 755,000 people globally per year, costing around 25.2 bill…
ISEF · 2019
Physics and Astronomy
This study investigates the use of Electrochemical Impedance Spectroscopy (EIS) to create equivalent circuits for human keratinocyte cells in Dulbecco’s Modified Eagle Media (DMEM) with and…
ISEF · 2019
Biomedical and Health Sciences
At what point do our psychological needs compel us to ignore possible health risks? Could we be turning a blind eye to the possibly harmful effects caused by a simple communication device? A…
ISEF · 2019
Computational Biology and Bioinformatics Fourth Award
MicroRNAs (miRNAs) are small noncoding RNA molecules that are implicated in many gene expression pathways. Because they can degrade genes before translation, they have been extensively resea…
ISEF · 2019
Translational Medical Science
Head and neck squamous cell carcinoma (HNSCC) comprises approximately 90% of all head and neck cancers and represents the sixth most common type of cancer worldwide. Surgery, radiotherapy an…
ISEF · 2019
Physics and Astronomy
This project sought to determine whether Dark Matter dominated galaxies are nucleated. In January of 2015, an article was published that sparked interest in the scientific community. The sci…
ISEF · 2019
Materials Science
Bone implants are supporting structures in the body commonly used to treat fractures. Their integrity is threatened by bacterial biofilms that trigger an inflammatory response, loosening the…
ISEF · 2019
Materials Science
Indium Gallium Nitride (InGaN) is a promising candidate to make effective and environmentally friendly light emitting diodes (LEDs), used for electronics display, indoor lighting, and wirele…
ISEF · 2019
Computational Biology and Bioinformatics
Time resolved X-ray crystallography produces molecular movies of proteins at femtosecond resolution. The elucidation of an enzyme’s structural dynamics during its catalysis has major implica…
ISEF · 2019
Biomedical and Health Sciences
Purpose: There is in an estimated 7.9 million bone fractures annually in which 5-10% of these result in delayed healing and progression to chronic nonunions. One factor that has previously b…
ISEF · 2019
Cellular and Molecular Biology
Hydroxyurea (HU) is a ribonucleotide reductase inhibitor which is used to treat diseases such as HIV, sickle cell disease, and chronic myelogenous leukemia (1). Yet, new evidence suggests th…
ISEF · 2019
Translational Medical Science
Deregulation of the tumor suppressor p27kip1 results in the proliferation of common and aggressive cancers such as breast and prostate cancer. The purpose of this study is to investigate the…
ISEF · 2019
Biochemistry
Neurodegenerative disorders represent a global healthcare crisis impacting over 60 million individuals worldwide at an estimated cost of over 800 billion dollars, that is exacerbated by a re…
ISEF · 2019
Physics and Astronomy
The Wolf-Lundmark-Melotte galaxy is a dwarf, irregular galaxy located in the constellation Cetus, that has yet to be fully and accurately analyzed. RR Lyrae variable stars are short-period v…
ISEF · 2019
Biochemistry
Chemotaxis is the movement of an organism up and down a concentration gradient. The aim of this project is to test and observe the effects of different concentrations of glucose on the chemo…
ISEF · 2019
Cellular and Molecular Biology
Slime molds are single-celled organisms that combine interesting properties. We tested this organism’s reaction to a basic and anacidic environment. The slime mold Physarum polycephalum was…
ISEF · 2019
Behavioral and Social Sciences
PURPOSE: Patients often need to use their arms to assist with functional activities but after open heart surgery pushing with the arms is limited to minimize force across the healing sternum…