ISEF · 2023
Am I Effective?
Microbiology
The intent of this project is to identify the efficacy of antibacterial soap when compared to non-antibacterial soap. In 2016, the FDA banned antibacterial products which contained triclosan…
Microbiology science fair projects from 2023
Browse real student projects, abstracts, and awards.
ISEF · 2023
A Model for Reversing the Cardiotoxic Effects of Doxorubicin via Fisetin in Saccharomyces cerevisiae
Microbiology Fourth Award
Doxorubicin is a globally utilized drug for cancer treatment. This drug has unfortunate cardiotoxic side-effects through drug-induced functional loss of iron-regulatory proteins (IRP1, IRP2)…
ISEF · 2023
Analysis of Biofilms on Microplastics Sampled From Wastewater Treatment Plant Effluent
Microbiology
Microplastics have been a significant environmental pollutant that are recently beginning to be studied within the past decade. While their threats have been well-documented among a variety…
ISEF · 2023
Analysis of Osmoadaptation Systems in C. reinhardtii in Response to Osmotic Stress Produced by Toxic Brine Dumping Cycles
Microbiology
This project analyzes the efficacy of osmoadaptation systems in the algae Chlamydomonas reinhardtii in response to osmotic stress caused by brine dumping cycles from desalination plants. As…
ISEF · 2023
An Antimicrobial-Bacterial Cellulose-Manuka Honey Loaded Dressing for the Active Treatment and Monitoring of Wounds
Microbiology Fourth Award
Chronic wounds are a significant healthcare threat worldwide, affecting an estimated 6.5 million people in the U.S. and costing the healthcare system an estimated $25 billion annually (10).…
ISEF · 2023
Antibacterial Effects of Culinary Spices on Serratia marcescens and Bacillus cereus
Microbiology
According to the World Health Organization, there are 600 million cases of food borne diseases and 420,000 deaths each year. This disparity can be especially harmful and prevalent in develop…
ISEF · 2023
Antibiotic Resistance Genes Identified in the Thermal Hot Springs National Park Public Water
Microbiology
Hot Springs, Arkansas is a tourist town known for its geothermal hot springs, which contain microbial thermophiles that thrive at high temperatures. These springs have several sources of wat…
ISEF · 2023
Antimicrobial Effects of Tris (Ethylenediamine) Cobalt(III) Chloride - Cobalt Complex
Microbiology
Humans are commonly exposed to infectious fungal agents that live in the environment, the most common type being yeast infections. Global warming appears to be a contributing factor in the p…
ISEF · 2023
Antimicrobial Resistance of a Biofilm-Forming Pathogen Probed With Antipyretic Pharmaceuticals and Antibiotics
Microbiology
Experiment using in vitro science to offer an intelligence on the most synergistic combination between antibiotics and antipyretics against a familiar biofilm-forming pathogen, Staphylococcu…
ISEF · 2023
A Self-Disinfecting Nanomaterial for Future Space Travel
Microbiology Third Award
A big challenge of long term space travel and habitation is bacteria proliferation in the spacecraft and space station. Bacteria form threatening biofilms that jeopardize equipment and the h…
ISEF · 2023
Bi-Directional Hygiene: Using the Microbiome to Combat Nosocomial Infection
Microbiology
Overuse of chemical sterilization has applied selective pressure to the bacteria that colonize our surfaces, increasing their pathogenicity and resistance to treatment. A possible solution t…
ISEF · 2023
Biosynthetic Engineering of Novel Multifunctioning Electroactive Bacterial Cellulose-Carbon Nanotube Therapeutic Bandages for Rapid Clearance of Vancomycin-Intermediate Staphylococcus aureus
Microbiology First Award
Staphylococcus aureus (SA) kills over 330,000 people yearly, is becoming increasingly resistant to antibiotics, and can stop wounds from healing. This study engineered bacterial cellulose-ca…
ISEF · 2023
Brand vs. Natural
Microbiology
Can natural disinfectants, such as essential oils, be as effective as more potent, commonly used disinfectants? The goal of this experiment is to compare the effectiveness and safety of comm…
ISEF · 2023
Brush Up!
Microbiology
Purpose: To determine the best way to store your toothbrush and the best way to decontaminate your toothbrush. Procedure: Colonization Process 1. I brushed my teeth, and then right after bru…
ISEF · 2023
Carbonation vs. Bacterial Growth in Naturally Carbonated Springs
Microbiology
Water from the naturally carbonated springs in Soda Springs, Idaho, is commonly believed to be safe for human consumption. Using samples from a variety of carbonated and non-carbonated sprin…
ISEF · 2023
Characterization and Genomic Analysis of Novel Acinetobacter baumannii Phages EAb3 and EAb7 for the Treatment of Multidrug-Resistant Infections
Microbiology
Acinetobacter baumannii is a pathogenic bacterium associated with multi-drug resistant nosocomial infection that has been classified as an urgent threat by the CDC. Phage therapy is promisin…
ISEF · 2023
Combating Pseudomonas Resistance: Cloning of the ampC Gene Encoding for Beta-Lactamase and Development of a Non-Toxic Allosteric Inhibitory Cocktail Therapy to Eradicate Pseudomonas aeruginosa
Microbiology First Award
The opportunistic pathogen Pseudomonas aeruginosa causes fatal and chronic infections, with 124,000 deaths annually, due to its beta-lactamase-mediated resistance to beta-lactam antibiotics…
ISEF · 2023
Computer-Aided Investigation of the Influence of Microplastics on Paramecia
Microbiology Fourth Award
Microorganisms are essential to our environment because of their importance to many ecosystems. As a result of improper disposal, a wide variety of substances pollute the environment, includ…
ISEF · 2023
CRAB vs Pepper: The Effect of Bioenhancers on Ampicillin-Sulbactam as a Treatment Against A. baumannii
Microbiology
As more and more bacteria develop antibiotic resistance, bioenhancers (substances that enhance antibiotic performance) are emerging as potential solutions. We hypothesized that the bioenhanc…
ISEF · 2023
Designing a Personalized Probiotic to Prevent/Alleviate Type Two Diabetes and Inflammatory Bowel Disease
Microbiology
The human microbiome makes up 90% of the cells in our body and that makes us just 10% human. The microbiome has long been associated with several human diseases. Our microbiome in homeostasi…
ISEF · 2023
Detecting Prevotella and Sneathia in Adolescent Vaginal Microbiomes Using 16s rRNA Gene Sequencing and Spreading Awareness of Under-Recognized Women’s Health Issues Through CARE: A Health Marketing Campaign
Microbiology
Trichomonas vaginalis (TV) infections are the most prevalent sexually-transmitted infection (STI) globally, yet there remains a dearth of common knowledge about its often-asymptomatic transm…
ISEF · 2023
Development of Molecular Diagnostic Tool for Cotton Leaf Curl Disease (CLCuD) Using Betasatellite Based Molecular Marker
Microbiology Third Award
Cotton Leaf Curl Disease (CLCuD) is caused by viruses that belong to genus, begomovirus. Five different species of viruses interact with one Betasatellite, responsible for symptom developmen…
ISEF · 2023
Doctor Bartender: Phage Cocktails To Treat Multi-Drug Resistant Mycobacterium abscessus
Microbiology Third Award
Singapore’s rapidly aging society increases the population’s vulnerability to M. abscessus infections. This is an alarming trend as M. abscessus is notoriously difficult to treat due to extr…
ISEF · 2023
Effects of Sound Exposure on the Phosphorus Uptake of Polyphosphate-Accumulating Organisms
Microbiology Third Award
Phosphorus is a problematic pollutant; wastewater treatment plants use two methods to remove phosphorus from wastewater: chemical precipitation and biological nutrient removal. In the latter…
ISEF · 2023
Enhancing the Effectiveness of the Antibiotic Ampicillin Against Escherichia coli
Microbiology
Which variable will have the highest impact on increasing the effectiveness of antibiotics? Our goal was to find ways to increase antibiotic effectiveness. The real root of the issue is bact…
ISEF · 2023
Evaluating the Antimicrobial Properties of Materials in Kenya
Microbiology
Kenya’s third leading cause of death is diarrheal diseases that are contracted through contact with E.coli contaminated surfaces. The purpose of the experiment was to find a material that is…
ISEF · 2023
Fighting the Emerging Antibiotic Resistance in Wastewater
Microbiology
The development and spread of antibiotic resistance in wastewater poses a significant threat to both the environment and human health. Biofilm is a key factor that promotes antibiotic resist…
ISEF · 2023
Got Milk? Comparing the Acid Production of Bifidobacterium infantis When Grown in Different Milks
Microbiology
The purpose of this study was to determine if different types of milk affected the growth and acid production of Bifidobacterium infantis, a powerful probiotic crucial for human development.…
ISEF · 2023
Gut-Skin Axis Theory: A Novel Approach to Alleviating Eczema Symptoms by Identifying Direct Relationships Between the Gut and Skin Bacteria
Microbiology
This experiment’s purpose was to analyze the direct relationship between the gut bacteria E. coli and L. acidophilus and the skin bacteria S. epidermidis. To begin, a preliminary trial was p…
ISEF · 2023
Home Remedies of the Apis mellifera Kind vs. Streptococcus
Microbiology
In order to determine whether Apis mellifera home remedies were effective in preventing and shortening the time of Streptococcus salivarus, I tested raw natural honey, hydrogen peroxide, and…