Browse real student projects, abstracts, and awards.
ISEF · 2025
Microbiology
Tardigrades are one of the many organisms that have the capability of surviving extreme environments. They do this by going into a stasis known as cryptobiosis including the lack of water kn…
ISEF · 2025
Microbiology
Plant-based natural products are utilized as active ingredients in herbal medicines, and studying their bioactivities is necessary for evaluating their medicinal value. The present study aim…
ISEF · 2025
Microbiology
Antibiotic resistance is a major global health threat projected by the World Health Organization to cause 10 million deaths annually by 2050. Autolysins like AtlA, essential for bacterial ce…
ISEF · 2025
Microbiology
Importance: The likelihood of another COVID-19-level pandemic occurring within 100 years is currently predicted to be 17% and is expected to increase to 44% after the next six decades. Emerg…
ISEF · 2025
Microbiology
Water contamination poses a global challenge, particularly in regions relying on unlicensed artesian wells for agriculture and livestock without regulatory oversight. This study examines the…
ISEF · 2025
Microbiology
Antibiotic-resistant bacteria threaten a future where even minor infections may become untreatable. This growing concern has renewed interest in an old alternative—phage therapy. Phage thera…
ISEF · 2025
Microbiology
Antibiotics have been the main solution to combat bacterial infections, however their inappropriate use has caused health problems, like dysbacteriosis as well as the development of resistan…
ISEF · 2025
Microbiology
E. coli outbreaks linked to romaine lettuce in Yuma, Arizona, have been a persistent public health concern. This study explores a solution to mitigating bacterial contamination using sonific…
ISEF · 2025
Microbiology
The use of mouthwash is widely recommended by dental professionals and endorsed by organizations such as the American Dental Association for its potential to improve oral hygiene. This exper…
ISEF · 2025
Microbiology
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 is a powerful technology used for gene editing. While this method has opened many opportunities for scientific advance…
ISEF · 2025
Microbiology
Since the 1930s, antibiotics have revolutionized medicine and saved countless lives from bacterial infections. However, the rise of antimicrobial resistance has increasingly compromised thei…
ISEF · 2025
Microbiology
Halophiles have a vast range of uses, from biofuel production to pharmaceutical applications. Escherichia coli has one of the fastest duplication times of any organism, as low as twenty minu…
ISEF · 2025
Microbiology
Antibiotics are the most commonly used type of medicine currently available. Although this medicine is greatly beneficial towards those who need it, the cost of it can be expensive and dange…
ISEF · 2025
Microbiology
Whole-body deodorants are widely used, yet their impact on the vaginal microbiome is unknown. Many contain antibacterial components that may disrupt Lactobacillus, the dominant bacteria of t…
ISEF · 2025
Microbiology
Aliivibrio fischeri is a single-celled, gram-negative, rod-shaped bacterium that lives within the ocean. When in healthy waters, its cell membrane quorum senses with other bacterium near it…
ISEF · 2025
Microbiology
The World Health Organization reports Vibrio cholerae serogroup O139 as a high-priority pathogen that has the potential to precipitate the 8th cholera pandemic. This project explores the use…
ISEF · 2025
Microbiology
For my Science fair project, I investigated the cleanliness of public restrooms, specifically finding which area was the grossest. My hypothesis was that door handles would be the dirtiest s…
ISEF · 2025
Microbiology
Biosand filters are an effective way for rural or less-developed communities to purify water from local water sources. However, limited research has been done on how the addition of microorg…
ISEF · 2025
Microbiology
The rise of multidrug-resistant (MDR) bacteria presents an escalating challenge to traditional antibiotics, causing the exploration of alternative therapeutic strategies. A key mechanism of…
ISEF · 2025
Microbiology
Epstein Barr Virus (EBV) is a gammaherpesvirus infecting 90% of adults, and is associated with various diseases, including infectious mononucleosis, Hodgkin lymphoma, Burkitt lymphoma, and N…
ISEF · 2025
Microbiology
Microplastic pollution presents a significant environmental challenge, particularly in soil ecosystems, where its effects on microbial communities remain poorly understood. This study aimed…
ISEF · 2025
Microbiology
Pancreatic cancer remains one of the most lethal diseases, primarily due to its asymptomatic progression and late-stage diagnosis, which severely limits treatment options and reduces surviva…
ISEF · 2025
Microbiology
Oral mucositis is an inflammation that causes pain and ulcers that affect cancer patients undergoing radiotherapy and/or chemotherapy. The condition is marked by oral mucosa inflammation, wh…
ISEF · 2025
Microbiology
C1 compounds—methanol, formaldehyde, and formate—are toxic environmental pollutants associated with hazardous spills, water contamination, and severe health effects, including blindness, can…
ISEF · 2025
Microbiology
The Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is a highly infectious and contagious pathogen with a significant impact on the global swine industry, causing reproductive an…
ISEF · 2025
Microbiology
The dengue virus infects over 400 million people each year and can lead to organ failure and death. Until 2024, there was only one current vaccine option for dengue; however, studies have sh…
ISEF · 2025
Microbiology
Biofilms are dangerously formed by bacteria in threatening environments and are challenging to treat when a person is infected. Biofilms form due to stressors on the bacteria, and on the Int…
ISEF · 2025
Microbiology
Cryptococcus neoformans—a pathogenic yeast—poses a severe risk to immunocompromised individuals. Its polysaccharide capsule, primarily glucuronoxylomannan, is its chief virulence factor. Cal…
ISEF · 2025
Microbiology
Ticks are vectors for approximately 16 diseases or illnesses, and in 2021, 476,000 Americans were treated for Lyme disease (CDC 2021). According to the CDC, I. scapularis ticks are responsib…
ISEF · 2025
Microbiology
With the advent of biologic pharmaceuticals, it is necessary to consider how these therapeutic mechanisms can be utilized to combat growing global health concerns, namely antibiotic resistan…