Browse real student projects, abstracts, and awards.
ISEF · 2020
Computational Biology and Bioinformatics
The treatment of chronic wounds has long been a challenge to wound care professionals and presents a substantial economic burden to healthcare systems globally. Over $50 billion is spent on…
ISEF · 2020
Computational Biology and Bioinformatics
Detecting Alzheimer’s Disease (AD) at the earliest possible stage is key in advancing AD prevention and treatment but is challenged by confounders with the normal aging processes in addition…
ISEF · 2020
Computational Biology and Bioinformatics
Authors, Genes, Diseases, and Drugs in a Network (GADDNET) is a web-based platform that connects researchers and institutions via the genes and diseases they study. GADDNET can help research…
ISEF · 2020
Computational Biology and Bioinformatics
Cancer is a leading cause of death worldwide. Because the organ and cell type that generated the tumor determine a patient’s response to therapies, quick and accurate identification of the p…
ISEF · 2020
Computational Biology and Bioinformatics
The sequences of most proteins are inferred from the longest open reading frame (ORF) found in their parent mRNA. While the rule is simple and convenient, it does not model the underlying bi…
ISEF · 2020
Computational Biology and Bioinformatics
This investigation researches if using amino acids instead of nitrogenous bases in bacterial data storage systems protects against the corruption of the stored data due to mutations. The hyp…
ISEF · 2020
Computational Biology and Bioinformatics
Antimicrobial peptides (AMPs) are a growing field of therapeutics with lower risks of antimicrobial resistance compared to conventional antibiotics. However, experimentally testing peptides…
ISEF · 2020
Computational Biology and Bioinformatics
2 statistically likely, novel drug candidates for solute transporter protein member 5, SLC5, were identified in this study. Dysfunction of a roundworm orthologue of SLC5, sulp-5, was linked…
ISEF · 2020
Computational Biology and Bioinformatics
According to the FDA, approximately 1.3 million people are injured due to medicine errors annually in the United States. A large percentage of these people are the elderly and people with mu…
ISEF · 2020
Computational Biology and Bioinformatics
Parkinson’s Disease (PD) is a disorder that inhibits the dopaminergic neurons in the brain. Currently, there is no accurate non-clinical way to diagnose PD, forcing medical professionals to…
ISEF · 2020
Computational Biology and Bioinformatics
New species of bacteria are being discovered on a daily basis. Fast detection and risk characterization are vital for taking proper action. Current techniques and methods used for microbial…
ISEF · 2020
Computational Biology and Bioinformatics
Approximately 55,000 patients are treated daily in ICUs within the U.S., most of whom are extremely sick and require rapid clinical decision-making. However, copious patient data engenders i…
ISEF · 2020
Computational Biology and Bioinformatics
I set out to find the similarities between different aggregating proteins’ amino acid sequences and 3D conformations in neurodegenerative diseases (NDDs) using computational methods. Using t…
ISEF · 2020
Computational Biology and Bioinformatics
Models of metastasis-free survival based on microarray gene expression can be powerful tools for clinicians and have broad applications in risk quantification, genetic research, and palliati…
ISEF · 2020
Computational Biology and Bioinformatics
Cancer originates from genetic and non-genetic alterations which induce not only abnormal cell proliferation, but also abnormal migration. Local invasion involves motile cancer cells advanci…
ISEF · 2020
Computational Biology and Bioinformatics
Pancreatic cancer is a devastating and incurable disease with a 5-year survival rate of just 10%. Due to genetic alterations known as mutations, certain cancer-inhibiting and cell vitality g…
ISEF · 2020
Computational Biology and Bioinformatics
Colorectal cancer is the second highest cause of cancer occurrence and death in men and women in the United States combined. A specialist usually confirms their diagnosis by a careful micros…
ISEF · 2020
Computational Biology and Bioinformatics
Epilepsy is one of the most common neurological disorders worldwide, and the unpredictable nature of epileptic seizures makes life challenging for many patients. The objective of this study…
ISEF · 2020
Computational Biology and Bioinformatics
My research identifies novel ways to predict recurrence in triple-negative breast cancer patients. I used multiplexed ion beam imaging to analyze cell prevalence and protein expression in th…
ISEF · 2020
Computational Biology and Bioinformatics
When the conscious mind declares a movement in the body, the central nervous system carries a signal to the muscles by way of neurons. This signal causes the muscles to contract in the form…
ISEF · 2020
Computational Biology and Bioinformatics
Of the over 100 types of cancers that together claim 2,000 lives in the United States daily, neuroblastoma is the most common in children under the age of two. This project seeks to identify…
ISEF · 2020
Computational Biology and Bioinformatics
Abnormally stiff brain tissue is associated with neural damage and can indicate Alzheimer’s dementia, other dementias, and normal pressure hydrocephalus. Currently, early Alzheimer’s diagnos…
ISEF · 2020
Computational Biology and Bioinformatics
This experiment sought to determine if individuals with schizophrenia have observable differences in the genetics of their oral microbiomes compared to healthy individuals. This was done by…
ISEF · 2020
Computational Biology and Bioinformatics
The purpose of the project was to create a brain-computer interface headset prototype capable of allowing patients with motor impairments and paralysis to regain a range of mobility utilizin…
ISEF · 2019
Computational Biology and Bioinformatics
Computational modeling offers a powerful method for studying cause-effect relationships in biology. This is immensely valuable for creating synthetic biomimicry structures. Mimosa pudica is…
ISEF · 2019
Computational Biology and Bioinformatics Third Award
Plant field testing proves often a long and costly process crucial to the development of efficient agricultural techniques. We aimed to create a plant topology simulator that presents a sign…
ISEF · 2019
Computational Biology and Bioinformatics
The 2.4-fold increase in thyroid cancer over recent decades and variation across regions indicate that environmental factors may be influencers, including I-131 released during nuclear testi…
ISEF · 2019
Computational Biology and Bioinformatics
Antibiotics can be used to cure bacterial infections. Antibiotics target various structures and processes within the cell such as protein synthesis, cell membrane integrity and cell wall syn…
ISEF · 2019
Computational Biology and Bioinformatics Third Award
A plummet in the research productivity of drug discovery has been observed in recent decades, with higher costs, longer timelines, and lower success rates of drug candidates in clinical tria…
ISEF · 2019
Computational Biology and Bioinformatics
Around the globe, G6PD enzyme deficiency is one of the widely-encountered diseases. There are more than 140 variants but the Mediterranean variant is commonly seen in the world. Therefore, t…