Browse real student projects, abstracts, and awards.
ISEF · 2022
Computational Biology and Bioinformatics First Award
Replication errors represent two-thirds of cancer mutations. A novel replication error subset, recurrent repeat contractions (rRCs), lack systematic examination in cancers due to complex amp…
ISEF · 2022
Computational Biology and Bioinformatics Third Award
The speed of ribosome movement along an mRNA transcript is a critical determinant of protein synthesis. Ribosome pause sites, or regions along an mRNA transcript where translating ribosomes…
ISEF · 2022
Computational Biology and Bioinformatics
Motor neurons are the essential cells connecting the brain and muscles, translating our thoughts and needs into actions and response. Here, we analyze a previously published dataset to explo…
ISEF · 2022
Computational Biology and Bioinformatics
The purpose of this experiment is to determine the relationship of breastfeeding and other social and economic factors to infant mortality on the Louisiana and national level. The researcher…
ISEF · 2022
Computational Biology and Bioinformatics
Each year, over two million people globally are afflicted by potentially life-threatening antibiotic-resistant infections, and many scientists believe that antibiotic-resistant superbugs may…
ISEF · 2022
Computational Biology and Bioinformatics Fourth Award
Cancer is one of the deadliest illnesses in the world, and to find a cure for cancer, information must be obtained on the human body’s response to tumors. The purpose of this study was to id…
ISEF · 2022
Computational Biology and Bioinformatics
Cancer metastasis poses a significant threat to global public health, accounting for an estimated 90% of cancer-related deaths, due to a lack of effective anti-metastatic agents. The overexp…
ISEF · 2022
Computational Biology and Bioinformatics
As burgeoning crises have exposed failures of the drug discovery cycle - an inability to quickly and effectively develop new drugs - artificial intelligence-based drug repositioning models a…
ISEF · 2021
Computational Biology and Bioinformatics Fourth Award
Diversity generating retroelements (DGRs) are genetic elements that promote hyper mutations in specific regions of the genome. The targeted mutations of DGRs allow positive traits to manifes…
ISEF · 2021
Computational Biology and Bioinformatics
This study aims to develop a network for prominent chronic illnesses and neurodegenerative diseases, factoring in preexisting conditions, lifestyle decisions, and an individual’s environment…
ISEF · 2021
Computational Biology and Bioinformatics Third Award
Amyloid-beta is an intrinsically disordered protein involved in neurodegenerative disorders. Previously, amyloid-beta was considered “undruggable” due to its shape-shifting properties. Howev…
ISEF · 2021
Computational Biology and Bioinformatics Fourth Award
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder characterized by death of upper and lower motor neurons and progressive paralysis of the extremities. ALS is a compl…
ISEF · 2021
Computational Biology and Bioinformatics Second Award
Our survival depends on the brain's adaptation of information processing to changing cognitive demands; this ability stems from the interactions of specialized brain networks. At rest, netwo…
ISEF · 2021
Computational Biology and Bioinformatics
??-helical coiled coils are protein substructures that play important roles in a wide range of biological events. Some types of coiled coils are used by various viruses (eg SARS-CoV2) to ent…
ISEF · 2021
Computational Biology and Bioinformatics
The microscopic structure of bone contributes to its resistance to crack propagation and high damage tolerance under mechanical loading. In everyday life, bone accumulates tiny fractures, ca…
ISEF · 2021
Computational Biology and Bioinformatics
Neurodegenerative diseases are one of the highest causes of death within the world. The WHO reported in 2016 that Alzheimer’s Disease and dementia were the 5th highest cause of death interna…
ISEF · 2021
Computational Biology and Bioinformatics
This research studied the gene expression profiles of small nuclear RNA (snRNA) and small nucleolar RNA (snoRNA) in Preeclampsia (PE), compared to term and idiopathic (iPTB) patients. The pu…
ISEF · 2021
Computational Biology and Bioinformatics Third Award
The cocktail party problem renders conversation difficult for hard-of-hearing individuals in multi-speaker environments. Current hearing aids cannot amplify the primary speaker's voice alone…
ISEF · 2021
Computational Biology and Bioinformatics
Recent rise in COVID-19 cases has highlighted the need for effective and targeted measures to reduce the spread of the virus. Consequently, app-based tracing strategies have been proposed as…
ISEF · 2021
Computational Biology and Bioinformatics
Current processes of drug discovery are too long, expensive, and ineffective. Companies undergo years of research and development without the certainty of obtaining conclusive results. Drug…
ISEF · 2021
Computational Biology and Bioinformatics Third Award
Scoliosis is a condition of abnormal spinal curvature with approximately 60,000 U.S. pediatric patients undergoing surgery or being placed into braces each year. Skeletal maturity assessment…
ISEF · 2021
Computational Biology and Bioinformatics
Cancer threatens millions of individuals every year and remains a central issue in the scientific community. It’s important to search for new alternative treatments, and anticancer peptides…
ISEF · 2021
Computational Biology and Bioinformatics
Cancer is a leading cause of human death worldwide, yet quick and accurate identification of the primary cancer site is still lacking. Owing to its ability to differentiate similar tumors an…
ISEF · 2021
Computational Biology and Bioinformatics Fourth Award
Current techniques of target identification in drug development are costly, lengthy, and function with high degrees of uncertainty that a drug can succeed in modulating a target. To address…
ISEF · 2021
Computational Biology and Bioinformatics
Seizures, sudden bursts of electrical activity in cortical neurons, occur frequently in neonates (1-28 days old) and are a common emergency in the NICU. Timely and proper treatment is crucia…
ISEF · 2021
Computational Biology and Bioinformatics
Wolbachia, a species of endosymbiotic intracellular bacteria found in a diverse set of species, is most notable for its role in vector control strategies to reduce the spread of diseases tha…
ISEF · 2021
Computational Biology and Bioinformatics
To limit the spread of COVID-19, government policies are necessary. Current research focuses primarily on documenting proposed policies rather than assessing the efficacy of said proposals.…
ISEF · 2021
Computational Biology and Bioinformatics
In this work, I studied cas9 protein, one of the proteins of the CRISPR-Cas bacterial defense system. It was chosen because a genome editing system based on it is currently under development…
ISEF · 2021
Computational Biology and Bioinformatics Fourth Award
Alzheimer’s Disease is a progressive neurodegenerative disease that results in memory loss and a general cognitive decline, afflicting approximately 45 million people worldwide with the rate…
ISEF · 2021
Computational Biology and Bioinformatics
Melanoma is one of the most fatal forms of skin cancer and is often very difficult to differentiate from other benign skin lesions. However, if detected at its early stages, it can almost al…