Browse real student projects, abstracts, and awards.
ISEF · 2023
Computational Biology and Bioinformatics
The malaria parasite, Plasmodium, infects over 200 million people annually and causes over 500,000 deaths, primarily impacting developing countries. After a decline within the last decade, m…
ISEF · 2023
Computational Biology and Bioinformatics
The rapid mutation of COVID-19 has made the pandemic prolonged, requiring flexible implementation of virus mutation, immunity, and anti-pandemic policies. However, traditional mathematical a…
ISEF · 2023
Computational Biology and Bioinformatics Third Award
Pediatric Neuroblastoma (NB) is one of the most common cancers among infants, with 90% of its cases occurring in children under the age of five and only 50% of youth with high-risk NB surviv…
ISEF · 2023
Computational Biology and Bioinformatics
Aging is the most important risk factor associated with many diseases such as cancer and Alzheimer's disease. While many studies focused on the prediction of aging cross-sectionally, few met…
ISEF · 2023
Computational Biology and Bioinformatics
Several breast cancer patients develop resistance to multiple chemotherapeutic agents. ATP-binding cassette (ABC) family of drug transporters have been hypothesized to be potentially involve…
ISEF · 2023
Computational Biology and Bioinformatics
EEGs are an important tool used by clinicians to diagnose neurological abnormalities such as epilepsy, and by medical researchers to map the functions of different components of the brain. H…
ISEF · 2023
Computational Biology and Bioinformatics
In this project, we propose the design and implementation of a new programming language that is specifically tailored for bioinformatics and computational science. The language has a simple…
ISEF · 2023
Computational Biology and Bioinformatics Fourth Award
Cancer's molecular heterogeneity and complexity pose significant treatment challenges. Drug combinations have recently been employed to enhance cancer therapy due to their synergistic effect…
ISEF · 2023
Computational Biology and Bioinformatics Second Award
Cells have evolved the process of translational regulation to rapidly fine-tune protein expression to suit intracellular needs. Ribosome velocity during translation elongation is a key contr…
ISEF · 2023
Computational Biology and Bioinformatics Second Award
The spread and transmission of SARS-CoV-2 and other viruses can lead to various mutations that cause significant spikes in infections. It is essential for researchers to study virus genome s…
ISEF · 2023
Computational Biology and Bioinformatics
CARM1 is a methyltransferase that methylates the BAF155 in the SWI/SNF protein complex, leading to cell proliferation and migration via the c-MYC pathway. SKI-73. EZM 2302, and TP-064 are th…
ISEF · 2023
Computational Biology and Bioinformatics
The role of deep learning in the recognition of morphological structures in histopathological data is heavily stunted by extreme variations that may exist in the datasets that these deep lea…
ISEF · 2023
Computational Biology and Bioinformatics
GABAA receptor (GABAAR), a pentameric ligand-gated ion channel, is activated by GABA, a major inhibitory neurotransmitter in the human brain. GABAAR dysfunction is implicated in several CNS…
ISEF · 2023
Computational Biology and Bioinformatics Third Award
Aortic aneurysms have increased in the past two decades and affect about 2.9 million people. Although surgical treatments have become increasingly sophisticated, there is a lack of efficient…
ISEF · 2023
Computational Biology and Bioinformatics
Developments in microscopy imaging have allowed for in depth study of biological systems at a level never previously reached. One such method is RNA fluorescence in situ hybridization (FISH)…
ISEF · 2023
Computational Biology and Bioinformatics Third Award
Litsea cubeba (Lauraceae) is a woody plant which is widely distributed in Vietnam. Its fruit essential oil (FEO) showed a potent effect on the central nervous system (CNS). However, the neur…
ISEF · 2023
Computational Biology and Bioinformatics
Gene deletion can be used in lower eukaryotes to show the protein-protein interactions in complexes. The Sin3 complex is a chromatin remodeling complex, that has been studied extensively in…
ISEF · 2023
Computational Biology and Bioinformatics
The COVID-19 pandemic has been ravaging on for more than 2 years now, ever since it was declared a pandemic in early March of 2020. Wastewater-based epidemiology (WBE) has been used in track…
ISEF · 2023
Computational Biology and Bioinformatics
Alzheimer’s Disease (AD) is a debilitating neurodegenerative condition, characterized by amyloid-beta plaque deposition in the brain. Focused ultrasound (FU) may have a therapeutic modulatin…
ISEF · 2023
Computational Biology and Bioinformatics
As burgeoning crises have exposed failures of the drug discovery cycle - an inability to quickly and effectively develop new drugs - artificial intelligence-based drug repositioning models a…
ISEF · 2023
Computational Biology and Bioinformatics
Malaria is a life-threatening disease, caused by plasmodium parasites, that affects nearly half of the world's population, particularly in Africa, where Plasmodium falciparum is the most com…
ISEF · 2023
Computational Biology and Bioinformatics
While bacteriophages show strong potential as therapeutics for bacterial infections, too little about their genomic structure and content is understood for widespread implementation. The pur…
ISEF · 2023
Computational Biology and Bioinformatics
Lung cancer is one of the most significant causes of death among all diseases. Specifically, non-small cell lung cancer (NSCLC) accounts for 87% of this daunting disease. Single-cell RNA-seq…
ISEF · 2022
Computational Biology and Bioinformatics Fourth Award
Alzheimer’s Disease, described by several researchers as the public health crisis of the 21st century, is a devastating neurodegenerative disorder of gradual onset, clinically characterized…
ISEF · 2022
Computational Biology and Bioinformatics
Diabetic retinopathy, a condition in which a diabetic individual may experience vision impairment or complete blindness due to the heightened amount of blood sugar in the body, is expected t…
ISEF · 2022
Computational Biology and Bioinformatics
With over 11 percent of people over the age of 65 developing this detrimental disease and being in the top 10 most common chronic conditions for adults over 65, Alzheimer's disease is a detr…
ISEF · 2022
Computational Biology and Bioinformatics
Rheumatoid Arthritis (RA) is an inflammatory autoimmune disease that affects 23 million people worldwide. It is a clinically heterogeneous disorder characterized by the attack of inflammator…
ISEF · 2022
Computational Biology and Bioinformatics
Background: Cancer is the second leading cause of death globally. The heterogeneous nature of cancers with multiple subtypes makes them challenging to treat. We hypothesized that a computati…
ISEF · 2022
Computational Biology and Bioinformatics
Purpose: To create a machine learning model that could identify drugs that could be effective against Multi-Drug Resistant Tuberculosis. Procedure: The Assay Central TB dataset was acquired…
ISEF · 2022
Computational Biology and Bioinformatics
According to the WHO, cancer resulted in 10 million deaths in 2020, a leading cause of death, and studies show that on average any particular class of drugs is ineffective for 75% of all pat…